SV2003000741A - Compuesto lactamico x-13170 - Google Patents

Compuesto lactamico x-13170

Info

Publication number
SV2003000741A
SV2003000741A SV2001000741A SV2001000741A SV2003000741A SV 2003000741 A SV2003000741 A SV 2003000741A SV 2001000741 A SV2001000741 A SV 2001000741A SV 2001000741 A SV2001000741 A SV 2001000741A SV 2003000741 A SV2003000741 A SV 2003000741A
Authority
SV
El Salvador
Prior art keywords
lactamic
compound
procedures
prepare
methyl
Prior art date
Application number
SV2001000741A
Other languages
English (en)
Inventor
Thomas Mitchell Koenig
James Edmund Audia
David Mitchell
Stacey Leigh Mcdaniel
Lynne Ann Buccilli
Gary Lowell Engel
James Abraham Aikins
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SV2003000741A publication Critical patent/SV2003000741A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA DIHIDRATO CRISTALINO DE(N)-(S) -2-HIDROXI-3-METIL -BUTIRIL)-1-AMINO-3-METIL-4-,5,6,7- TETRAHIDRO-2H-3-BENZOAZEPIN -2-ONA, COMPOSICIONES DEL MISMO Y PROCEDIMIENTOS PARA PREPARARLO Y PROCEDIMIENTOS PARA PREPARAR SUS INTERMEDIOS
SV2001000741A 2000-11-17 2001-11-16 Compuesto lactamico x-13170 SV2003000741A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24965600P 2000-11-17 2000-11-17

Publications (1)

Publication Number Publication Date
SV2003000741A true SV2003000741A (es) 2003-01-13

Family

ID=22944436

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2001000741A SV2003000741A (es) 2000-11-17 2001-11-16 Compuesto lactamico x-13170

Country Status (33)

Country Link
US (1) US20040248878A1 (es)
EP (1) EP1353910B1 (es)
JP (1) JP4116431B2 (es)
KR (1) KR20030045194A (es)
CN (2) CN100516047C (es)
AR (1) AR031356A1 (es)
AT (1) ATE362919T1 (es)
AU (2) AU2432102A (es)
BR (1) BR0115424A (es)
CA (1) CA2425497C (es)
CY (1) CY1106682T1 (es)
CZ (1) CZ20031340A3 (es)
DE (1) DE60128587T2 (es)
DK (1) DK1353910T3 (es)
DZ (1) DZ3454A1 (es)
EA (1) EA006919B1 (es)
EC (1) ECSP034598A (es)
ES (1) ES2286162T3 (es)
HR (1) HRP20030385A2 (es)
HU (1) HUP0301862A3 (es)
IL (1) IL155275A0 (es)
MX (1) MXPA03004250A (es)
MY (1) MY141607A (es)
NO (1) NO325217B1 (es)
PE (1) PE20020798A1 (es)
PL (1) PL211018B1 (es)
PT (1) PT1353910E (es)
SK (1) SK287794B6 (es)
SV (1) SV2003000741A (es)
TW (1) TWI235151B (es)
UA (1) UA77165C2 (es)
WO (1) WO2002040451A2 (es)
ZA (1) ZA200303411B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74849C2 (en) * 2000-11-17 2006-02-15 Lilly Co Eli Lactam
RU2423353C1 (ru) 2002-12-20 2011-07-10 Глэксо Груп Лимитед Новые производные бензазепина
KR20110010824A (ko) 2003-01-14 2011-02-07 아레나 파마슈티칼스, 인크. 대사 조절제로서의 １,２,３-삼치환된 아릴 및 헤테로아릴 유도체, 및 당뇨병 및 고혈당증을 비롯한 이에 관련된 장애의 예방 및 치료
RU2404968C2 (ru) 2005-04-08 2010-11-27 Дайити Санкио Компани, Лимитед Пиридилдиметилсульфоновое производное
WO2007088878A1 (ja) 2006-01-31 2007-08-09 Api Corporation ベンゾアゼピノン類の製造方法
TW200920362A (en) 2007-09-11 2009-05-16 Daiichi Sankyo Co Ltd Alkylsulfone derivatives
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
US10894787B2 (en) 2010-09-22 2021-01-19 Arena Pharmaceuticals, Inc. Modulators of the GPR119 receptor and the treatment of disorders related thereto
KR101899014B1 (ko) 2012-01-06 2018-09-17 삼성전자주식회사 비엘디씨 모터의 제어 장치 및 그 방법
CN102690231B (zh) * 2012-04-11 2014-07-09 南京友杰医药科技有限公司 治疗阿尔茨海默病潜在药物司马西特的合成方法
US20160067306A1 (en) 2013-04-19 2016-03-10 National University Corporation Hokkaido University Treatment agent for cognitive impairment induced by amyloid beta-protein, therapeutic agent for alzheimer's disease, and treatment method and pathological analysis method related to these
MX2021011472A (es) 2015-01-06 2022-08-17 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
KR102603199B1 (ko) 2015-06-22 2023-11-16 아레나 파마슈티칼스, 인크. Ｓ1ｐ1 수용체-관련 장애에서의 사용을 위한 (ｒ)-2-(7-(4-시클로펜틸-3-(트리플루오로메틸)벤질옥시)-1,2,3,4-테트라히드로시클로-펜타[ｂ]인돌-3-일)아세트산 (화합물 1)의 결정성 ｌ-아르기닌 염
WO2018151873A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
EP4126952A1 (en) 2020-03-26 2023-02-08 Seagen Inc. Methods of treating multiple myeloma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA002100B1 (ru) * 1996-12-23 2001-12-24 Элан Фармасьютикалз, Инк. ЦИКЛОАЛКИЛЬНЫЕ СОЕДИНЕНИЯ, ЛАКТАМЫ, ЛАКТОНЫ И РОДСТВЕННЫЕ СОЕДИНЕНИЯ, СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ И СПОСОБЫ ИНГИБИРОВАНИЯ ВЫСВОБОЖДЕНИЯ И/ИЛИ СИНТЕЗА β-АМИЛОИДНОГО ПЕПТИДА С ПОМОЩЬЮ УКАЗАННЫХ СОЕДИНЕНИЙ
JP2002518481A (ja) * 1998-06-22 2002-06-25 エラン ファーマシューティカルズ，インコーポレイテッド β−アミロイドペプチドの放出および／またはその合成を阻害するための化合物
JP2003513958A (ja) * 1999-11-09 2003-04-15 イーライ・リリー・アンド・カンパニー β−アミロイドペプチド放出および／またはその合成を阻害するために有用なβ−アミノ酸化合物

Also Published As

Publication number Publication date
AU2432102A (en) 2002-05-27
EA006919B1 (ru) 2006-04-28
EP1353910B1 (en) 2007-05-23
JP2004521084A (ja) 2004-07-15
CZ20031340A3 (cs) 2004-06-16
KR20030045194A (ko) 2003-06-09
NO20032215L (no) 2003-07-16
JP4116431B2 (ja) 2008-07-09
SK5432003A3 (en) 2004-09-08
PL360991A1 (en) 2004-09-20
WO2002040451A2 (en) 2002-05-23
ECSP034598A (es) 2003-06-25
UA77165C2 (en) 2006-11-15
DZ3454A1 (fr) 2002-05-23
TWI235151B (en) 2005-07-01
HUP0301862A3 (en) 2007-09-28
EP1353910A2 (en) 2003-10-22
AR031356A1 (es) 2003-09-17
CY1106682T1 (el) 2012-05-23
PL211018B1 (pl) 2012-03-30
NO20032215D0 (no) 2003-05-15
ZA200303411B (en) 2004-08-02
IL155275A0 (en) 2003-11-23
PT1353910E (pt) 2007-08-20
ES2286162T3 (es) 2007-12-01
PE20020798A1 (es) 2002-09-06
HRP20030385A2 (en) 2003-08-31
CA2425497C (en) 2010-08-17
DK1353910T3 (da) 2007-09-10
HUP0301862A2 (hu) 2003-09-29
CN100516047C (zh) 2009-07-22
CA2425497A1 (en) 2002-05-23
US20040248878A1 (en) 2004-12-09
CN101624372A (zh) 2010-01-13
DE60128587T2 (de) 2008-01-31
EA200300579A1 (ru) 2003-12-25
NO325217B1 (no) 2008-02-25
CN1575282A (zh) 2005-02-02
SK287794B6 (sk) 2011-10-04
WO2002040451A3 (en) 2003-08-28
MY141607A (en) 2010-05-31
MXPA03004250A (es) 2003-09-22
ATE362919T1 (de) 2007-06-15
AU2002224321B2 (en) 2006-10-19
DE60128587D1 (de) 2007-07-05
BR0115424A (pt) 2003-10-21

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