DK1181069T3 - Apparat og fremgangsmåde til aerosolisering af en pulverformig pharmaceutisk formulering - Google Patents

Apparat og fremgangsmåde til aerosolisering af en pulverformig pharmaceutisk formulering

Info

Publication number
DK1181069T3
DK1181069T3 DK00936239T DK00936239T DK1181069T3 DK 1181069 T3 DK1181069 T3 DK 1181069T3 DK 00936239 T DK00936239 T DK 00936239T DK 00936239 T DK00936239 T DK 00936239T DK 1181069 T3 DK1181069 T3 DK 1181069T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical formulation
aerosolizing
gas stream
powdered pharmaceutical
receptacle
Prior art date
Application number
DK00936239T
Other languages
English (en)
Inventor
Carlos Schuler
Steve Paboojian
Derrick Tuttle
Aneesh K Bakshi
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Application granted granted Critical
Publication of DK1181069T3 publication Critical patent/DK1181069T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • A61M15/0036Piercing means hollow piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8218Gas operated
    • A61M2205/8225Gas operated using incorporated gas cartridges for the driving gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Nozzles (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
DK00936239T 1999-05-28 2000-05-24 Apparat og fremgangsmåde til aerosolisering af en pulverformig pharmaceutisk formulering DK1181069T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13651899P 1999-05-28 1999-05-28
US55626200A 2000-04-24 2000-04-24

Publications (1)

Publication Number Publication Date
DK1181069T3 true DK1181069T3 (da) 2006-10-09

Family

ID=26834378

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00936239T DK1181069T3 (da) 1999-05-28 2000-05-24 Apparat og fremgangsmåde til aerosolisering af en pulverformig pharmaceutisk formulering

Country Status (13)

Country Link
EP (1) EP1181069B1 (da)
JP (1) JP4377076B2 (da)
KR (1) KR100813784B1 (da)
AT (2) ATE331544T1 (da)
AU (1) AU764541B2 (da)
CA (1) CA2375680C (da)
CY (1) CY1105401T1 (da)
DE (2) DE60029099T2 (da)
DK (1) DK1181069T3 (da)
ES (1) ES2265944T3 (da)
MX (1) MXPA01012246A (da)
PT (1) PT1181069E (da)
WO (1) WO2000072904A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6668827B2 (en) 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
US7905230B2 (en) 2001-05-09 2011-03-15 Novartis Ag Metered dose inhaler with lockout
ATE508735T1 (de) 2001-12-19 2011-05-15 Novartis Ag Pulmonale verabreichung von aminoglykosiden
WO2003057593A1 (en) 2001-12-21 2003-07-17 Nektar Therapeutics Capsule package with moisture barrier
US6941980B2 (en) 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
US7516741B2 (en) 2002-12-06 2009-04-14 Novartis Ag Aerosolization apparatus with feedback mechanism
US7669596B2 (en) 2002-12-31 2010-03-02 Novartis Pharma Ag Aerosolization apparatus with rotating capsule
SI1615689T1 (sl) 2003-04-09 2016-05-31 Novartis Ag Naprava za aerosolizacijo s poravnalnim vodilom za prebadanje kapsule
SI1610850T2 (sl) 2003-04-09 2020-11-30 Novartis Ag Naprava za aerosolizacijo s ščitom za vstopni zrak
US8869794B1 (en) 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
US8513204B2 (en) 2004-06-21 2013-08-20 Novartis Ag Compositions comprising amphotericin B, mehods and systems
MXPA06015220A (es) 2004-06-21 2007-12-13 Nektar Therapeutics Composiciones comprendiendo anfotericina b, metodos y sistemas.
JP5727927B2 (ja) 2008-05-15 2015-06-03 ノバルティス アーゲー フルオロキノロンの肺送達
ES2750359T3 (es) 2009-03-18 2020-03-25 Incarda Therapeutics Inc Dosis unitarias, aerosoles, kits y procedimientos para tratar afecciones cardíacas mediante administración pulmonar
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
US9452139B2 (en) 2013-03-14 2016-09-27 Novartis Ag Respirable agglomerates of porous carrier particles and micronized drug
BR112015020443A8 (pt) 2013-03-14 2019-11-12 Novartis Ag formulação em pó para inalação, seus usos e seu processo de preparação, e composição farmacêutica
US10010294B2 (en) 2016-02-01 2018-07-03 Incarda Therapeutics, Inc. Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation
EP3621616A4 (en) 2017-05-10 2021-01-13 InCarda Therapeutics, Inc. UNIT DOSES, AEROSOLS, KITS, AND METHODS FOR TREATING HEART CONDITIONS BY PULMONARY ADMINISTRATION
AU2018271873B2 (en) 2017-05-22 2023-11-02 Insmed Incorporated Glycopeptide derivative compounds and uses thereof
EP3768378B1 (en) 2018-03-22 2025-08-06 InCarda Therapeutics, Inc. A novel method to slow ventricular rate
US11020384B2 (en) 2019-08-01 2021-06-01 Incarda Therapeutics, Inc. Antiarrhythmic formulation
KR102182794B1 (ko) * 2019-09-04 2020-11-25 (주)코스메디션 초음파유화 및 고압가스분사를 이용한 레스베라트롤 및 페룰산 균질유화 조성물 제조 방법
US20240299353A1 (en) 2021-03-12 2024-09-12 Alvarius Pharmaceuticals Ltd. Compositions and methods for treating addictions comprising 5-meo-dmt
KR102620750B1 (ko) * 2021-08-20 2024-01-02 주식회사 케이티앤지 니코틴 이행부를 포함하는 에어로졸 흡입기
KR102675542B1 (ko) * 2021-09-01 2024-06-14 주식회사 케이티앤지 에어로졸 생성기
KR102768524B1 (ko) * 2022-09-14 2025-02-17 주식회사 케이티앤지 인헤일러

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3616971A (en) * 1970-02-24 1971-11-02 Precision Valve Corp Dispenser and metering valve therefor
SE408265B (sv) * 1975-12-12 1979-06-05 Draco Ab Anordning for koldioxiddriven endosaerosol, avsedd for inhalering
US4999976A (en) * 1989-08-03 1991-03-19 The Kartridg Pak Co. Means and method for ultrasonic gassing of aerosols
GB9414236D0 (en) * 1994-07-14 1994-08-31 V A R I S P A Aerosol metering valves
US5875776A (en) * 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US6003512A (en) * 1997-11-13 1999-12-21 Lovelace Respiratory Research Institute Dust gun-aerosol generator and generation
US6105929A (en) * 1997-11-14 2000-08-22 Salter Labs Control valve for gas supply to a nebulizer

Also Published As

Publication number Publication date
KR100813784B1 (ko) 2008-03-13
ES2265944T3 (es) 2007-03-01
ATE331544T1 (de) 2006-07-15
DE60041610D1 (de) 2009-04-02
MXPA01012246A (es) 2002-08-12
KR20020016632A (ko) 2002-03-04
EP1181069B1 (en) 2006-06-28
AU764541B2 (en) 2003-08-21
PT1181069E (pt) 2006-11-30
DE60029099T2 (de) 2007-01-11
JP2003500176A (ja) 2003-01-07
ATE422924T1 (de) 2009-03-15
WO2000072904A1 (en) 2000-12-07
AU5158500A (en) 2000-12-18
CY1105401T1 (el) 2010-04-28
CA2375680A1 (en) 2000-12-07
CA2375680C (en) 2010-01-26
JP4377076B2 (ja) 2009-12-02
EP1181069A1 (en) 2002-02-27
DE60029099D1 (de) 2006-08-10

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