DE60029099D1 - Gerät und verfahren zur aerosolisierung einer pharmazeutischen pulverzusammensetzung - Google Patents

Gerät und verfahren zur aerosolisierung einer pharmazeutischen pulverzusammensetzung

Info

Publication number
DE60029099D1
DE60029099D1 DE60029099T DE60029099T DE60029099D1 DE 60029099 D1 DE60029099 D1 DE 60029099D1 DE 60029099 T DE60029099 T DE 60029099T DE 60029099 T DE60029099 T DE 60029099T DE 60029099 D1 DE60029099 D1 DE 60029099D1
Authority
DE
Germany
Prior art keywords
aerosolizing
pharmaceutical formulation
powder composition
gas stream
pharmaceutical powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60029099T
Other languages
English (en)
Other versions
DE60029099T2 (de
Inventor
Carlos Schuler
Steve Paboojian
K Bakshi
Derrick Tuttle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nektar Therapeutics
Original Assignee
Nektar Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nektar Therapeutics filed Critical Nektar Therapeutics
Publication of DE60029099D1 publication Critical patent/DE60029099D1/de
Application granted granted Critical
Publication of DE60029099T2 publication Critical patent/DE60029099T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A61M15/0036—Piercing means hollow piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8218—Gas operated
    • A61M2205/8225—Gas operated using incorporated gas cartridges for the driving gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Nozzles (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
DE60029099T 1999-05-28 2000-05-24 Gerät und verfahren zur aerosolisierung einer pharmazeutischen pulverzusammensetzung Expired - Lifetime DE60029099T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13651899P 1999-05-28 1999-05-28
US136518P 1999-05-28
US55626200A 2000-04-24 2000-04-24
US556262 2000-04-24
PCT/US2000/014227 WO2000072904A1 (en) 1999-05-28 2000-05-24 Apparatus and method for dispensing metered amount of aerosolized medication

Publications (2)

Publication Number Publication Date
DE60029099D1 true DE60029099D1 (de) 2006-08-10
DE60029099T2 DE60029099T2 (de) 2007-01-11

Family

ID=26834378

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60041610T Expired - Lifetime DE60041610D1 (de) 1999-05-28 2000-05-24 Gerät zum Abgeben von abgemessenen Mengen von Medikamente beinhaltendem Aerosol
DE60029099T Expired - Lifetime DE60029099T2 (de) 1999-05-28 2000-05-24 Gerät und verfahren zur aerosolisierung einer pharmazeutischen pulverzusammensetzung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60041610T Expired - Lifetime DE60041610D1 (de) 1999-05-28 2000-05-24 Gerät zum Abgeben von abgemessenen Mengen von Medikamente beinhaltendem Aerosol

Country Status (13)

Country Link
EP (1) EP1181069B1 (de)
JP (1) JP4377076B2 (de)
KR (1) KR100813784B1 (de)
AT (2) ATE331544T1 (de)
AU (1) AU764541B2 (de)
CA (1) CA2375680C (de)
CY (1) CY1105401T1 (de)
DE (2) DE60041610D1 (de)
DK (1) DK1181069T3 (de)
ES (1) ES2265944T3 (de)
MX (1) MXPA01012246A (de)
PT (1) PT1181069E (de)
WO (1) WO2000072904A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US7326691B2 (en) 2004-06-21 2008-02-05 Nektar Therapeutics Compositions comprising amphotericin B, methods, and systems
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6668827B2 (en) 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
US7905230B2 (en) 2001-05-09 2011-03-15 Novartis Ag Metered dose inhaler with lockout
EP1458360B1 (de) 2001-12-19 2011-05-11 Novartis AG Pulmonale verabreichung von aminoglykosiden
JP4739672B2 (ja) 2001-12-21 2011-08-03 ネクター セラピューティクス 湿気のバリアを有するカプセルパッケージ
US6941980B2 (en) 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
US7516741B2 (en) 2002-12-06 2009-04-14 Novartis Ag Aerosolization apparatus with feedback mechanism
US7669596B2 (en) 2002-12-31 2010-03-02 Novartis Pharma Ag Aerosolization apparatus with rotating capsule
US8869794B1 (en) 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
HUE026950T2 (en) 2003-04-09 2016-08-29 Novartis Ag Nozzle with guide wire for puncturing the capsule
PL1610850T3 (pl) 2003-04-09 2012-11-30 Novartis Ag Urządzenie rozpylające z osłoną wlotu powietrza
US8513204B2 (en) 2004-06-21 2013-08-20 Novartis Ag Compositions comprising amphotericin B, mehods and systems
MX2010012452A (es) 2008-05-15 2011-03-15 Novartis Ag Star Suministro pulmonar de una fluoro-quinolona.
WO2010107964A1 (en) 2009-03-18 2010-09-23 Pleiades Cardio-Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
US9452139B2 (en) 2013-03-14 2016-09-27 Novartis Ag Respirable agglomerates of porous carrier particles and micronized drug
KR102074543B1 (ko) 2013-03-14 2020-02-06 노파르티스 아게 분무-블렌딩을 통한 분무-건조 제제의 탈무정형화
CA3012333A1 (en) 2016-02-01 2017-08-10 Incarda Therapeutics, Inc. Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation
KR20200003199A (ko) 2017-05-10 2020-01-08 인카다 테라퓨틱스, 인크. 폐 투여에 의해 심장 병태를 치료하기 위한 단위 용량, 에어로졸, 키트 및 방법
US20200368312A1 (en) 2017-05-22 2020-11-26 Insmed Incorporated Glycopeptide derivative compounds and uses thereof
US10744087B2 (en) 2018-03-22 2020-08-18 Incarda Therapeutics, Inc. Method to slow ventricular rate
US11007185B2 (en) 2019-08-01 2021-05-18 Incarda Therapeutics, Inc. Antiarrhythmic formulation
KR102182794B1 (ko) * 2019-09-04 2020-11-25 (주)코스메디션 초음파유화 및 고압가스분사를 이용한 레스베라트롤 및 페룰산 균질유화 조성물 제조 방법
EP4304582A1 (de) 2021-03-12 2024-01-17 Alvarius Pharmaceuticals Ltd. Zusammensetzungen und verfahren zur behandlung von sucht mit 5-meo-dmt
KR20240036847A (ko) * 2022-09-14 2024-03-21 주식회사 케이티앤지 인헤일러

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3616971A (en) * 1970-02-24 1971-11-02 Precision Valve Corp Dispenser and metering valve therefor
SE408265B (sv) * 1975-12-12 1979-06-05 Draco Ab Anordning for koldioxiddriven endosaerosol, avsedd for inhalering
US4999976A (en) * 1989-08-03 1991-03-19 The Kartridg Pak Co. Means and method for ultrasonic gassing of aerosols
GB9414236D0 (en) * 1994-07-14 1994-08-31 V A R I S P A Aerosol metering valves
US5875776A (en) * 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
US6003512A (en) * 1997-11-13 1999-12-21 Lovelace Respiratory Research Institute Dust gun-aerosol generator and generation
US6105929A (en) * 1997-11-14 2000-08-22 Salter Labs Control valve for gas supply to a nebulizer

Also Published As

Publication number Publication date
ATE422924T1 (de) 2009-03-15
EP1181069B1 (de) 2006-06-28
DK1181069T3 (da) 2006-10-09
KR100813784B1 (ko) 2008-03-13
PT1181069E (pt) 2006-11-30
JP4377076B2 (ja) 2009-12-02
CA2375680A1 (en) 2000-12-07
ATE331544T1 (de) 2006-07-15
KR20020016632A (ko) 2002-03-04
AU5158500A (en) 2000-12-18
EP1181069A1 (de) 2002-02-27
JP2003500176A (ja) 2003-01-07
MXPA01012246A (es) 2002-08-12
AU764541B2 (en) 2003-08-21
CY1105401T1 (el) 2010-04-28
DE60041610D1 (de) 2009-04-02
ES2265944T3 (es) 2007-03-01
DE60029099T2 (de) 2007-01-11
WO2000072904A1 (en) 2000-12-07
CA2375680C (en) 2010-01-26

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Legal Events

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8364 No opposition during term of opposition