DK1159296T3 - Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly) - Google Patents
Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly)Info
- Publication number
- DK1159296T3 DK1159296T3 DK00920461T DK00920461T DK1159296T3 DK 1159296 T3 DK1159296 T3 DK 1159296T3 DK 00920461 T DK00920461 T DK 00920461T DK 00920461 T DK00920461 T DK 00920461T DK 1159296 T3 DK1159296 T3 DK 1159296T3
- Authority
- DK
- Denmark
- Prior art keywords
- nmeval
- dphe
- cyclo
- gly
- asp
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19910727 | 1999-03-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1159296T3 true DK1159296T3 (da) | 2004-09-27 |
Family
ID=7900511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00920461T DK1159296T3 (da) | 1999-03-11 | 2000-03-01 | Fremgangsmåde til fremstilling af cyclo-(Asp-DPhe-NMeVal-Arg-Gly) |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6822074B1 (pl) |
| EP (1) | EP1159296B1 (pl) |
| JP (1) | JP4762418B2 (pl) |
| KR (1) | KR100645002B1 (pl) |
| CN (1) | CN1200947C (pl) |
| AR (1) | AR022905A1 (pl) |
| AT (1) | ATE267839T1 (pl) |
| AU (1) | AU762540B2 (pl) |
| BR (1) | BR0008863A (pl) |
| CA (1) | CA2366694C (pl) |
| CZ (1) | CZ299879B6 (pl) |
| DE (1) | DE50006598D1 (pl) |
| DK (1) | DK1159296T3 (pl) |
| ES (1) | ES2221616T3 (pl) |
| HK (1) | HK1044780B (pl) |
| HU (1) | HUP0200369A3 (pl) |
| ID (1) | ID30126A (pl) |
| MY (1) | MY120083A (pl) |
| NO (1) | NO330030B1 (pl) |
| PL (1) | PL202996B1 (pl) |
| PT (1) | PT1159296E (pl) |
| RU (1) | RU2243974C2 (pl) |
| SE (1) | SE1159296T5 (pl) |
| SK (1) | SK285387B6 (pl) |
| TW (1) | TWI269798B (pl) |
| UA (1) | UA71608C2 (pl) |
| WO (1) | WO2000053627A1 (pl) |
| ZA (1) | ZA200108335B (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0814519D0 (en) | 2008-08-08 | 2008-09-17 | Imp Innovations Ltd | Process |
| US20120058905A1 (en) * | 2009-05-15 | 2012-03-08 | Covello Patrick S | DNA Sequences Encoding Caryophyllaceae and Caryophyllaceae-Like Cyclopeptide Precursors and Methods of Use |
| AU2010251385B2 (en) * | 2009-05-20 | 2016-04-14 | Merck Patent Gmbh | Novel solid materials of {[2S, 5R,8S,11S)-5-benzyl-11-(3-guanidino-propyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid} and methods for obtaining them |
| EP2509583B1 (en) | 2009-12-10 | 2019-05-15 | Merck Patent GmbH | Pharmaceutical composition comprising oligopeptides, preferably cilengitide |
| CN103717205B (zh) | 2011-06-09 | 2017-04-12 | 默克专利股份公司 | 用西仑吉肽在载体中的悬浮液治疗癌症和癌症转移 |
| EP3802559A1 (en) * | 2018-06-05 | 2021-04-14 | DSM IP Assets B.V. | Methods for the synthesis of arginine-containing peptides |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1038741B (de) * | 1956-09-14 | 1958-09-11 | Eberhard Brecklinghaus | Aus Gummi oder einem anderen elastischen Werkstoff bestehender Kantenschoner fuer Treppenstufen aus Beton od. dgl. |
| US3630660A (en) * | 1968-10-31 | 1971-12-28 | Burlington Industries Inc | Process for removal of moisture and/or solvents from textile materials |
| UA43823C2 (uk) * | 1992-07-06 | 2002-01-15 | Мерк Патент Геселлшафт Міт Бесшренктер Хафтунг | ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ІНГІБУВАННЯ ІНТЕГРИН <font face="Symbol">a</font><sub>V</sub><font face="Symbol">b</font><sub>3</sub>-ОПОСЕРЕДКОВАНОЇ КЛІТИННОЇ АДГЕЗІЇ КЛІТИН ССАВЦІВ, СПОСІБ ЛІКУВАННЯ ТА ПРОФІЛАКТИКИ ЗАХВОРЮВАННЯ, АСОЦІЙОВАНОГО З ПОРУШЕННЯМ АДГЕЗІЇ КЛІТИН, СПОСІБ БЛОКУВАННЯ ЗВ'ЯЗУВАННЯ ФІБРИНОГЕНОМ ІНТЕГРИНУ, КОМПОЗИЦІЯ ДЛЯ ЗАГОЄННЯ РАН |
| JPH06263798A (ja) * | 1993-01-13 | 1994-09-20 | Takeda Chem Ind Ltd | βターン及びγターンを有する環状ペンタペプチド、その製造方法および用途 |
| DE69418353T2 (de) * | 1993-01-13 | 1999-10-28 | Takeda Chemical Industries, Ltd. | Cyclische Pentapeptide mit Beta-Turn und Gamma-Turn |
| DE4310643A1 (de) * | 1993-04-01 | 1994-10-06 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| EP0763061B1 (de) | 1994-06-02 | 2002-10-30 | Forssmann, Wolf-Georg, Prof. Dr. med. | Verfahren zur herstellung von cardiodilatin-fragmenten, hochgereinigte cardiodilatin-fragmente und zwischenprodukte zu deren herstellung |
| DE19534177A1 (de) | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| DE19538741A1 (de) | 1995-10-18 | 1997-04-24 | Merck Patent Gmbh | Cyclopeptidderivate |
| DE19613933A1 (de) | 1996-04-06 | 1997-10-09 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| BR9709514A (pt) * | 1996-05-31 | 1999-08-10 | Scripps Research Inst | Processo e composições úteis para a inibição de angiogénese mediada por alfa beta |
| DE19728524A1 (de) * | 1997-07-04 | 1999-01-07 | Merck Patent Gmbh | Cyclische Azapeptide |
-
2000
- 2000-01-03 UA UA2001106897A patent/UA71608C2/uk unknown
- 2000-03-01 PL PL349646A patent/PL202996B1/pl not_active IP Right Cessation
- 2000-03-01 CA CA2366694A patent/CA2366694C/en not_active Expired - Fee Related
- 2000-03-01 US US09/936,230 patent/US6822074B1/en not_active Expired - Fee Related
- 2000-03-01 SE SE00820481T patent/SE1159296T5/xx unknown
- 2000-03-01 DE DE50006598T patent/DE50006598D1/de not_active Expired - Lifetime
- 2000-03-01 AU AU41034/00A patent/AU762540B2/en not_active Ceased
- 2000-03-01 WO PCT/EP2000/001751 patent/WO2000053627A1/de active IP Right Grant
- 2000-03-01 SK SK1255-2001A patent/SK285387B6/sk not_active IP Right Cessation
- 2000-03-01 RU RU2001126541/04A patent/RU2243974C2/ru not_active IP Right Cessation
- 2000-03-01 KR KR1020017011291A patent/KR100645002B1/ko not_active IP Right Cessation
- 2000-03-01 CN CNB008048746A patent/CN1200947C/zh not_active Expired - Fee Related
- 2000-03-01 HU HU0200369A patent/HUP0200369A3/hu unknown
- 2000-03-01 AT AT00920461T patent/ATE267839T1/de active
- 2000-03-01 JP JP2000604062A patent/JP4762418B2/ja not_active Expired - Fee Related
- 2000-03-01 ID IDW00200102095A patent/ID30126A/id unknown
- 2000-03-01 BR BR0008863-3A patent/BR0008863A/pt active Search and Examination
- 2000-03-01 MY MYPI20000799A patent/MY120083A/en unknown
- 2000-03-01 ES ES00920461T patent/ES2221616T3/es not_active Expired - Lifetime
- 2000-03-01 CZ CZ20013214A patent/CZ299879B6/cs not_active IP Right Cessation
- 2000-03-01 EP EP00920461A patent/EP1159296B1/de not_active Expired - Lifetime
- 2000-03-01 PT PT00920461T patent/PT1159296E/pt unknown
- 2000-03-01 DK DK00920461T patent/DK1159296T3/da active
- 2000-03-07 TW TW089104103A patent/TWI269798B/zh not_active IP Right Cessation
- 2000-03-10 AR ARP000101079A patent/AR022905A1/es active IP Right Grant
-
2001
- 2001-09-10 NO NO20014383A patent/NO330030B1/no not_active IP Right Cessation
- 2001-10-10 ZA ZA200108335A patent/ZA200108335B/en unknown
-
2002
- 2002-08-29 HK HK02106365.2A patent/HK1044780B/zh not_active IP Right Cessation
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