DK1151082T3 - Sebocytter, sebocyt-cellelinie og anvendelsen heraf - Google Patents

Sebocytter, sebocyt-cellelinie og anvendelsen heraf

Info

Publication number
DK1151082T3
DK1151082T3 DK99963551T DK99963551T DK1151082T3 DK 1151082 T3 DK1151082 T3 DK 1151082T3 DK 99963551 T DK99963551 T DK 99963551T DK 99963551 T DK99963551 T DK 99963551T DK 1151082 T3 DK1151082 T3 DK 1151082T3
Authority
DK
Denmark
Prior art keywords
sebocytes
cell line
sebocyte cell
sebaceous gland
cells
Prior art date
Application number
DK99963551T
Other languages
English (en)
Inventor
Christos Zouboulis
Original Assignee
Christos Zouboulis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christos Zouboulis filed Critical Christos Zouboulis
Application granted granted Critical
Publication of DK1151082T3 publication Critical patent/DK1151082T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0625Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0633Cells of secretory glands, e.g. parotid gland, salivary glands, sweat glands, lacrymal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653Adipocytes; Adipose tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/305Growth hormone [GH], aka. somatotropin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/33Insulin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/395Thyroid hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • C12N2503/02Drug screening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK99963551T 1999-02-01 1999-12-15 Sebocytter, sebocyt-cellelinie og anvendelsen heraf DK1151082T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19903920A DE19903920B4 (de) 1999-02-01 1999-02-01 Sebozyten, Sebozyten-Zellinie und deren Verwendungen

Publications (1)

Publication Number Publication Date
DK1151082T3 true DK1151082T3 (da) 2006-04-10

Family

ID=7896032

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99963551T DK1151082T3 (da) 1999-02-01 1999-12-15 Sebocytter, sebocyt-cellelinie og anvendelsen heraf

Country Status (14)

Country Link
US (5) US20020034820A1 (da)
EP (1) EP1151082B1 (da)
JP (1) JP4514963B2 (da)
KR (1) KR100689120B1 (da)
CN (1) CN100366735C (da)
AT (1) ATE319813T1 (da)
AU (1) AU770518B2 (da)
CA (1) CA2360762C (da)
DE (2) DE19903920B4 (da)
DK (1) DK1151082T3 (da)
HU (1) HU226915B1 (da)
IL (2) IL144683A0 (da)
PL (1) PL194865B1 (da)
WO (1) WO2000046353A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10141443B4 (de) * 2001-08-23 2007-02-01 Christos C. Prof. Dr. Zouboulis Verwendung von molekularbiologisch hergestellten, nicht-viralen Wirkstoffen zur Behandlung der Akne
FR2960549B1 (fr) * 2010-05-25 2015-06-19 Univ Paris Curie Procede de culture d'adipocytes
CN102668885B (zh) * 2012-05-30 2013-06-05 北京市农林科学院 一种黄伞新菌株及其子实体栽培方法
DE102013015560A1 (de) 2013-09-20 2015-03-26 Cutech Srl. Ex vivo Kulturen auf Basis humaner Talgdrüsen und deren Verwendung als Screening Werkzeug
EP3249042B1 (en) * 2016-02-08 2018-08-01 Kao Corporation Method for producing mature sebaceous gland cells
US20180325938A1 (en) 2016-03-25 2018-11-15 Kao Corporation Method of evaluating or selecting androgen receptor activity regulator selective to sebaceous glands or hair follicles
EP3284817A1 (en) * 2016-08-18 2018-02-21 Phenocell Human sebocyte precursor cells, human sebocytes and in vitro methods for obtaining the same from human induced pluripotent stem cells (hipsc)
FR3061205A1 (fr) * 2016-12-22 2018-06-29 L'oreal Modele d'epithelium reconstruit sebocytaire differencie a partir de sebocytes humains primaires
CN109852576A (zh) * 2019-01-07 2019-06-07 施歌 一种永生化皮脂腺细胞株的构建方法
CN111088217B (zh) * 2019-12-20 2023-03-03 广东博溪生物科技有限公司 细胞培养基、细胞培养试剂盒及细胞培养方法
CN112608947B (zh) * 2020-12-28 2023-06-16 上海市皮肤病医院 一种永生化人皮脂腺细胞系的构建方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06509467A (ja) * 1991-04-04 1994-10-27 アメリカ合衆国 内皮細胞の不死化
AU4233297A (en) * 1996-08-23 1998-03-06 Arch Development Corporation Identification of activators and inhibitors of sebum formation
IT1293484B1 (it) * 1997-06-11 1999-03-01 Fidia Advanced Biopolymers Srl Materiale biologico comprendente una efficiente coltura di cellule e una matrice tridimensionale biocompatibile e biodegradabile

Also Published As

Publication number Publication date
IL144683A (en) 2008-04-13
US20140120569A1 (en) 2014-05-01
KR100689120B1 (ko) 2007-03-09
US20020034820A1 (en) 2002-03-21
PL194865B1 (pl) 2007-07-31
AU1980400A (en) 2000-08-25
CN100366735C (zh) 2008-02-06
US20110065142A1 (en) 2011-03-17
US20160237406A1 (en) 2016-08-18
DE19903920A1 (de) 2000-08-10
JP2002535984A (ja) 2002-10-29
CA2360762C (en) 2009-01-27
ATE319813T1 (de) 2006-03-15
PL350191A1 (en) 2002-11-18
JP4514963B2 (ja) 2010-07-28
CA2360762A1 (en) 2000-08-10
HUP0200048A2 (hu) 2002-05-29
EP1151082B1 (de) 2006-03-08
DE19903920B4 (de) 2005-08-25
WO2000046353A1 (de) 2000-08-10
HUP0200048A3 (en) 2006-02-28
IL144683A0 (en) 2002-06-30
DE59913210D1 (de) 2006-05-04
HU226915B1 (en) 2010-03-01
US20120225445A1 (en) 2012-09-06
EP1151082A1 (de) 2001-11-07
KR20020013495A (ko) 2002-02-20
CN1344314A (zh) 2002-04-10
AU770518B2 (en) 2004-02-26

Similar Documents

Publication Publication Date Title
DK1151082T3 (da) Sebocytter, sebocyt-cellelinie og anvendelsen heraf
ATE402407T1 (de) Kohlenstoff-nano-röhrchen-vorrichtung
HRP20050354B1 (da)
PT1109787E (pt) Arilpiperazinas e sua utilizacao como inibidores de metaloproteinases
DE69921522D1 (de) Gasgeschmierte langsamlaufende Gleitringdichtung
DE50105338D1 (de) Neuartige polymerbindersysteme mit ionischen flüssigkeiten
TR200002877T2 (tr) Sülfonamid türevleri
TR200101378T2 (tr) Taşınabilir bir telefon ve çalıştırmak için bir yöntem
DK1066392T3 (da) Vektorer til genmutagenese og gen-discovery
ATE319851T1 (de) Affinitätssensor für den nachweis spezifischer molekularer bindungsereignisse und dessen verwendung
DE50313510D1 (de) Zellkultureinsatz
DK0921857T3 (da) Flerbröndsplader med lav baggrund til fluorescensmålinger af biologiske og biokemiske pröver
EP2295956A3 (en) Manipulation of analytes using electric fields
MX2009010547A (es) Transferencia de punto de union de datos.
AR021292A1 (es) Una regleta de terminales para telecomunicaciones e ingenieria de datos y utilizacion de un dispositivo de apantallamiento en el interior de dicha regleta.
ATE209286T1 (de) Vorrichtung zum verbinden von armierten betonteilen
SE9802882D0 (sv) Kompositmaterial och dess användning
SE0301750D0 (sv) Module and Frame for Cable Entries or the Like
NO995188L (no) Hurtigstørknende hydraulisk bindemiddelsammensetning
ATE263325T1 (de) Einstückiger doppeldichtungsring
IT244203Y1 (it) Cerniera con leve di fissaggio al mobile
ATE483251T1 (de) Integrierter schaltkreis mit baublöcken
DE60144558D1 (de) Kontaktvorrichtung und ihre verwendung
ATE284590T1 (de) Modulares drahtloses endgerät
ATE442720T1 (de) Homebus-system