DK1143933T3 - Hidtil ukendte hydrogelisolerede cochleat-formuleringer, fremgangsmåde til fremstilling og deres anvendelse ved afgivelse af biologisk relevante molekyler - Google Patents
Hidtil ukendte hydrogelisolerede cochleat-formuleringer, fremgangsmåde til fremstilling og deres anvendelse ved afgivelse af biologisk relevante molekylerInfo
- Publication number
- DK1143933T3 DK1143933T3 DK00909961T DK00909961T DK1143933T3 DK 1143933 T3 DK1143933 T3 DK 1143933T3 DK 00909961 T DK00909961 T DK 00909961T DK 00909961 T DK00909961 T DK 00909961T DK 1143933 T3 DK1143933 T3 DK 1143933T3
- Authority
- DK
- Denmark
- Prior art keywords
- biologically relevant
- preparation
- relevant molecules
- cochleates
- delivering biologically
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000002502 liposome Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000005191 phase separation Methods 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Anesthesiology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/235,400 US6153217A (en) | 1999-01-22 | 1999-01-22 | Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents |
PCT/US2000/001684 WO2000042989A2 (fr) | 1999-01-22 | 2000-01-24 | Nouvelles formulations de structures cochleaires isolees dans des hydrogels, procede de preparation et utilisation de celles-ci pour administrer des molecules biologiquement utiles |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1143933T3 true DK1143933T3 (da) | 2007-11-26 |
Family
ID=22885334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00909961T DK1143933T3 (da) | 1999-01-22 | 2000-01-24 | Hidtil ukendte hydrogelisolerede cochleat-formuleringer, fremgangsmåde til fremstilling og deres anvendelse ved afgivelse af biologisk relevante molekyler |
Country Status (12)
Country | Link |
---|---|
US (7) | US6153217A (fr) |
EP (1) | EP1143933B1 (fr) |
JP (1) | JP2002535267A (fr) |
AT (1) | ATE367800T1 (fr) |
AU (1) | AU3213300A (fr) |
CA (1) | CA2358505C (fr) |
CY (1) | CY1106916T1 (fr) |
DE (1) | DE60035669T2 (fr) |
DK (1) | DK1143933T3 (fr) |
ES (1) | ES2290019T3 (fr) |
PT (1) | PT1143933E (fr) |
WO (1) | WO2000042989A2 (fr) |
Families Citing this family (62)
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US6153217A (en) | 1999-01-22 | 2000-11-28 | Biodelivery Sciences, Inc. | Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents |
AU3111401A (en) * | 2000-01-24 | 2001-07-31 | Biodelivery Sciences, Inc. | New cochleate formulations, process of preparation and their use for the delivery of biologically relevant molecules |
DE10154464B4 (de) * | 2001-11-08 | 2005-10-20 | Max Delbrueck Centrum | Oral verabreichbare pharmazeutische Zubereitung umfassend liposomal verkapseltes Taxol |
US20030219473A1 (en) * | 2002-03-26 | 2003-11-27 | Leila Zarif | Cochleates made with purified soy phosphatidylserine |
US20040092727A1 (en) * | 2002-11-13 | 2004-05-13 | Biopharm Solutions Inc. | Cochleates without metal cations as bridging agents |
WO2004012709A1 (fr) * | 2002-08-06 | 2004-02-12 | Tuo Jin | Structure cochleaires exemptes d'agents de pontage du type cations de metaux |
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US20050244522A1 (en) * | 2004-04-30 | 2005-11-03 | Carrara Dario Norberto R | Permeation enhancer comprising genus Curcuma or germacrone for transdermal and topical administration of active agents |
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Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US4663161A (en) * | 1985-04-22 | 1987-05-05 | Mannino Raphael J | Liposome methods and compositions |
US4871488A (en) * | 1985-04-22 | 1989-10-03 | Albany Medical College Of Union University | Reconstituting viral glycoproteins into large phospholipid vesicles |
US4990291A (en) * | 1986-04-15 | 1991-02-05 | The United States Of America As Represented By The Secretary Of The Navy | Method of making lipid tubules by a cooling process |
US5269979A (en) * | 1988-06-08 | 1993-12-14 | Fountain Pharmaceuticals, Inc. | Method for making solvent dilution microcarriers |
WO1990015595A1 (fr) * | 1989-06-22 | 1990-12-27 | Vestar, Inc. | Procede d'encapsulage |
US5994318A (en) * | 1993-10-04 | 1999-11-30 | Albany Medical College | Cochleate delivery vehicles |
US5840707A (en) * | 1993-10-04 | 1998-11-24 | Albany Medical College | Stabilizing and delivery means of biological molecules |
US5643574A (en) * | 1993-10-04 | 1997-07-01 | Albany Medical College | Protein- or peptide-cochleate vaccines and methods of immunizing using the same |
CA2246754C (fr) | 1996-02-22 | 2002-10-22 | Raphael James Mannino | Vecteurs d'apport de structures cochleaires |
US6120751A (en) * | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
US6153217A (en) | 1999-01-22 | 2000-11-28 | Biodelivery Sciences, Inc. | Nanocochleate formulations, process of preparation and method of delivery of pharmaceutical agents |
-
1999
- 1999-01-22 US US09/235,400 patent/US6153217A/en not_active Expired - Fee Related
-
2000
- 2000-01-24 CA CA2358505A patent/CA2358505C/fr not_active Expired - Fee Related
- 2000-01-24 PT PT00909961T patent/PT1143933E/pt unknown
- 2000-01-24 DK DK00909961T patent/DK1143933T3/da active
- 2000-01-24 DE DE60035669T patent/DE60035669T2/de not_active Expired - Lifetime
- 2000-01-24 AT AT00909961T patent/ATE367800T1/de active
- 2000-01-24 EP EP00909961A patent/EP1143933B1/fr not_active Expired - Lifetime
- 2000-01-24 ES ES00909961T patent/ES2290019T3/es not_active Expired - Lifetime
- 2000-01-24 WO PCT/US2000/001684 patent/WO2000042989A2/fr active IP Right Grant
- 2000-01-24 JP JP2000594446A patent/JP2002535267A/ja active Pending
- 2000-01-24 AU AU32133/00A patent/AU3213300A/en not_active Abandoned
- 2000-07-11 US US09/613,840 patent/US6592894B1/en not_active Expired - Lifetime
-
2003
- 2003-04-23 US US10/421,358 patent/US20030228355A1/en not_active Abandoned
-
2005
- 2005-01-18 US US11/040,615 patent/US20050186265A1/en not_active Abandoned
-
2007
- 2007-10-08 CY CY20071101285T patent/CY1106916T1/el unknown
-
2008
- 2008-04-23 US US12/148,942 patent/US20090028904A1/en not_active Abandoned
-
2012
- 2012-04-06 US US13/441,030 patent/US20120294901A1/en not_active Abandoned
-
2013
- 2013-12-31 US US14/145,268 patent/US20140220109A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20120294901A1 (en) | 2012-11-22 |
DE60035669D1 (de) | 2007-09-06 |
CA2358505A1 (fr) | 2000-07-27 |
US20050186265A1 (en) | 2005-08-25 |
US20030228355A1 (en) | 2003-12-11 |
DE60035669T2 (de) | 2008-02-07 |
ATE367800T1 (de) | 2007-08-15 |
JP2002535267A (ja) | 2002-10-22 |
PT1143933E (pt) | 2007-09-03 |
EP1143933B1 (fr) | 2007-07-25 |
AU3213300A (en) | 2000-08-07 |
US20140220109A1 (en) | 2014-08-07 |
WO2000042989A3 (fr) | 2000-11-30 |
CY1106916T1 (el) | 2012-09-26 |
US20090028904A1 (en) | 2009-01-29 |
CA2358505C (fr) | 2010-04-06 |
ES2290019T3 (es) | 2008-02-16 |
US6153217A (en) | 2000-11-28 |
US6592894B1 (en) | 2003-07-15 |
EP1143933A2 (fr) | 2001-10-17 |
WO2000042989A2 (fr) | 2000-07-27 |
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