DK1140170T3 - Antistoffragmenter til topisk behandling af öjensygdomme - Google Patents
Antistoffragmenter til topisk behandling af öjensygdommeInfo
- Publication number
- DK1140170T3 DK1140170T3 DK99966798T DK99966798T DK1140170T3 DK 1140170 T3 DK1140170 T3 DK 1140170T3 DK 99966798 T DK99966798 T DK 99966798T DK 99966798 T DK99966798 T DK 99966798T DK 1140170 T3 DK1140170 T3 DK 1140170T3
- Authority
- DK
- Denmark
- Prior art keywords
- antibody fragments
- eye diseases
- topical treatment
- sub
- disorder
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/624—Disulfide-stabilized antibody (dsFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPP8033A AUPP803399A0 (en) | 1999-01-05 | 1999-01-05 | Novel therapeutic and diagnostic agent for ocular disorders |
AUPQ3305A AUPQ330599A0 (en) | 1999-10-07 | 1999-10-07 | Novel agents for treatment and diagnosis of ocular disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1140170T3 true DK1140170T3 (da) | 2006-10-23 |
Family
ID=25645965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99966798T DK1140170T3 (da) | 1999-01-05 | 1999-12-24 | Antistoffragmenter til topisk behandling af öjensygdomme |
Country Status (9)
Country | Link |
---|---|
US (1) | US6773916B1 (ja) |
EP (1) | EP1140170B1 (ja) |
JP (3) | JP5483789B2 (ja) |
AT (1) | ATE330631T1 (ja) |
CA (1) | CA2348488C (ja) |
DE (1) | DE69932084T2 (ja) |
DK (1) | DK1140170T3 (ja) |
NZ (1) | NZ511219A (ja) |
WO (1) | WO2000040262A1 (ja) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6670321B1 (en) * | 1998-12-30 | 2003-12-30 | The Children's Medical Center Corporation | Prevention and treatment for retinal ischemia and edema |
US6773916B1 (en) * | 1999-01-05 | 2004-08-10 | The Flinders University Of South Australia | Agents and methods for treatment and diagnosis of ocular disorders |
WO2001030386A1 (en) * | 1999-10-22 | 2001-05-03 | Biogen, Inc. | Use of a cd40:cd154 binding interruptor to treat immunological complications of the eye |
CA2432978C (en) | 2000-12-22 | 2012-08-28 | Medlyte, Inc. | Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor |
JP2002208294A (ja) * | 2001-01-12 | 2002-07-26 | Toshiba Corp | リダンダンシーシステムを有する半導体記憶装置 |
AU2002316887A1 (en) * | 2001-05-03 | 2002-11-18 | Novartis Ag | Anti-ige antibody to treat ocular allergies |
JP4838968B2 (ja) * | 2001-09-28 | 2011-12-14 | 参天製薬株式会社 | 薬物−ポリエチレングリコール結合体を含有する眼組織内注入剤 |
US9320792B2 (en) | 2002-11-08 | 2016-04-26 | Ablynx N.V. | Pulmonary administration of immunoglobulin single variable domains and constructs thereof |
AU2003286003B2 (en) * | 2002-11-08 | 2011-05-26 | Ablynx N.V. | Stabilized single domain antibodies |
US20060034845A1 (en) | 2002-11-08 | 2006-02-16 | Karen Silence | Single domain antibodies directed against tumor necrosis factor alpha and uses therefor |
WO2004041865A2 (en) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Stabilized single domain antibodies |
ES2383525T3 (es) | 2003-11-05 | 2012-06-21 | Sarcode Bioscience Inc. | Moduladores de la adhesión celular |
US20050197310A1 (en) * | 2004-01-30 | 2005-09-08 | Orna Mor | Oligoribonucleotides and methods of use thereof for treatment of fibrotic conditions and other diseases |
CA2609053C (en) * | 2005-05-17 | 2017-04-25 | Sarcode Corporation | Compositions and methods for treatment of eye disorders |
US9198981B2 (en) * | 2006-02-01 | 2015-12-01 | The University Of Kentucky | Modulation of angiogenesis |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US20070218007A1 (en) * | 2006-03-17 | 2007-09-20 | Allergan, Inc. | Ophthalmic visualization compositions and methods of using same |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
WO2007131050A2 (en) * | 2006-05-02 | 2007-11-15 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
US9217749B2 (en) | 2006-05-31 | 2015-12-22 | Lpath, Inc. | Immune-derived moieties reactive against lysophosphatidic acid |
US9274129B2 (en) | 2006-05-31 | 2016-03-01 | Lpath, Inc. | Methods and reagents for detecting bioactive lipids |
US9274130B2 (en) | 2006-05-31 | 2016-03-01 | Lpath, Inc. | Prevention and treatment of pain using antibodies to lysophosphatidic acid |
SI2046382T1 (sl) * | 2006-07-10 | 2016-12-30 | ESBATech an Alcon Biomedical Research Unit LLC | Protitelesa scFv, ki prehajajo epitelijske in/ali endotelijske plasti |
US20080031903A1 (en) * | 2006-07-27 | 2008-02-07 | Andrea Gambotto | Method of treating ocular infections |
PT2087002E (pt) | 2006-10-27 | 2014-11-26 | Lpath Inc | Composições e métodos para a ligação de esfingosina-1- fosfato |
WO2009052187A2 (en) * | 2007-10-15 | 2009-04-23 | Stokes John P | Convergent well irradiating plaque for choroidal melanoma |
EP3797775A1 (en) | 2007-10-19 | 2021-03-31 | Novartis AG | Compositions and methods for treatment of diabetic retinopathy |
WO2009139817A2 (en) | 2008-04-15 | 2009-11-19 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
CN102065893A (zh) * | 2008-04-15 | 2011-05-18 | 萨可德公司 | Lfa-1拮抗剂向胃肠系统的递送 |
JP2011518155A (ja) * | 2008-04-15 | 2011-06-23 | サーコード コーポレイション | 免疫関連障害の局所治療に使用するためのエアゾール化lfa−1アンタゴニスト |
ES2763703T3 (es) * | 2008-04-15 | 2020-05-29 | Sarcode Bioscience Inc | Antagonistas de LFA-1 tópicos utilizados en el tratamiento localizado de trastornos inmunes |
US7772006B2 (en) * | 2008-08-21 | 2010-08-10 | Paul Tornambe | Agent detection and/or quantitation in a biological fluid |
US8871202B2 (en) | 2008-10-24 | 2014-10-28 | Lpath, Inc. | Prevention and treatment of pain using antibodies to sphingosine-1-phosphate |
WO2010129033A2 (en) * | 2009-04-29 | 2010-11-11 | Calmune Corporation | Modified antibodies for passive immunotherapy |
US8378105B2 (en) * | 2009-10-21 | 2013-02-19 | Sarcode Bioscience Inc. | Crystalline pharmaceutical and methods of preparation and use thereof |
WO2011097609A1 (en) * | 2010-02-08 | 2011-08-11 | Cornell University | Model system of acanthamoeba keratitis syndrome and method for selecting a treatment thereof |
WO2013113820A1 (en) | 2012-02-02 | 2013-08-08 | Esbatech - A Novartis Company Llc | Antibody-containing sustained-release formulation for ocular administration |
MX2015001098A (es) | 2012-07-25 | 2015-09-25 | Sarcode Bioscience Inc | Inhibidor del antigeno-1 asociado a la funcion del linfocito (lfa-1) y polimorfo del mismo. |
CN104884049A (zh) | 2012-11-08 | 2015-09-02 | 克莱尔塞德生物医学股份有限公司 | 用于在人类受试者中治疗眼部疾病的方法和装置 |
CN104955480A (zh) * | 2013-01-25 | 2015-09-30 | 西蒙有限公司 | 用于选择性减少循环的生物活性可溶性tnf的组合物以及用于治疗tnf介导的疾病的方法 |
NO2991479T3 (ja) * | 2013-03-14 | 2018-03-17 | ||
MX2015015282A (es) | 2013-05-03 | 2016-02-26 | Clearside Biomedical Inc | Aparatos y metodos para inyeccion ocular. |
US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
US20160310417A1 (en) | 2013-12-20 | 2016-10-27 | Emory University | Formulations and Methods For Targeted Ocular Delivery of Therapeutic Agents |
MX2016017028A (es) | 2014-06-20 | 2017-08-07 | Clearside Biomedical Inc | Canula de diametro variable y metodos para el control de la profundidad de insercion para administracion de medicamentos. |
CA2960583C (en) * | 2014-09-09 | 2019-01-15 | Arturo Solis Herrera | Methods for treating and preventing ocular diseases, disorders, and conditions with melanin and melanin analogs, precursors, and derivatives |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
CN107405360B (zh) * | 2015-01-20 | 2019-08-27 | 维洛克生物制药有限责任公司 | 新颖碘伏组合物及其使用方法 |
EP3173098A1 (en) | 2015-11-27 | 2017-05-31 | Assistance Publique-Hopitaux De Paris | Immunostimulatory compositions |
US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
WO2017184667A1 (en) * | 2016-04-19 | 2017-10-26 | The United States Of America As Represented By The Secretary Of The Army | Device and method for isolation of corneal endothelial cells |
EP3452165A1 (en) | 2016-05-02 | 2019-03-13 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
CN110177527B (zh) | 2016-08-12 | 2022-02-01 | 科尼尔赛德生物医学公司 | 用于调节药剂递送用针的插入深度的装置和方法 |
CN109706238B (zh) | 2017-10-26 | 2023-04-07 | 珠海岐微生物科技有限公司 | 一种老年性黄斑病变的检测与治疗方法 |
EP4353315A3 (en) | 2018-11-14 | 2024-05-15 | Smilebiotek Zhuhai Limited | Animal models, screening methods, and treatment methods for intraocular diseases or disorders |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS568324A (en) * | 1979-07-04 | 1981-01-28 | Mochida Pharmaceut Co Ltd | Infectious disease remedy for external and ophthalmologic application |
US5616122A (en) * | 1986-11-04 | 1997-04-01 | Baylor College Of Medicine | Methods and compositions for preventing secondary cataracts |
JPH07121879B2 (ja) * | 1986-11-14 | 1995-12-25 | 富士レビオ株式会社 | 点眼用免疫グロブリン製剤 |
IL97075A0 (en) * | 1990-02-14 | 1992-03-29 | Alcon Lab Inc | Topical pharmaceutical composition containing an alkyl saccharide |
DE69229275T2 (de) * | 1991-10-04 | 1999-12-30 | Us Health | Herstellung eines arzneimittels zur behandlung von augenentzündung durch blockierung von zelladhäsionsmolekulen |
DE69232604T2 (de) * | 1992-11-04 | 2002-11-07 | City Of Hope Duarte | Antikörperkonstrukte |
WO1994014475A1 (en) * | 1992-12-21 | 1994-07-07 | Tanox Biosystems, Inc. | ALLERGEN-SPECIFIC IgA MONOCLONAL ANTIBODIES AND RELATED PRODUCTS FOR ALLERGY TREATMENT |
US5670132A (en) * | 1994-09-20 | 1997-09-23 | Immunomedics, Inc. | Modified radioantibody fragments for reduced renal uptake |
CA2228620A1 (en) * | 1995-08-07 | 1997-02-20 | John E. Oakes | Treatment of ocular inflammatory conditions with interleukin-10 |
EP0918858A1 (en) | 1996-05-10 | 1999-06-02 | Biogen, Inc. | Common gamma chain blocking agents |
JPH1180024A (ja) * | 1997-09-12 | 1999-03-23 | Toagosei Co Ltd | 角膜血管新生阻害剤 |
TWI259837B (en) * | 1998-05-11 | 2006-08-11 | Eidgenossische Tech Hochscule | Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis |
US6773916B1 (en) * | 1999-01-05 | 2004-08-10 | The Flinders University Of South Australia | Agents and methods for treatment and diagnosis of ocular disorders |
-
1999
- 1999-12-24 US US09/857,399 patent/US6773916B1/en not_active Expired - Lifetime
- 1999-12-24 DK DK99966798T patent/DK1140170T3/da active
- 1999-12-24 DE DE69932084T patent/DE69932084T2/de not_active Expired - Lifetime
- 1999-12-24 NZ NZ511219A patent/NZ511219A/en not_active IP Right Cessation
- 1999-12-24 AT AT99966798T patent/ATE330631T1/de not_active IP Right Cessation
- 1999-12-24 WO PCT/AU1999/001163 patent/WO2000040262A1/en active IP Right Grant
- 1999-12-24 CA CA2348488A patent/CA2348488C/en not_active Expired - Lifetime
- 1999-12-24 EP EP99966798A patent/EP1140170B1/en not_active Expired - Lifetime
- 1999-12-24 JP JP2000592017A patent/JP5483789B2/ja not_active Expired - Lifetime
-
2011
- 2011-01-27 JP JP2011014766A patent/JP5703039B2/ja not_active Expired - Lifetime
-
2013
- 2013-10-03 JP JP2013208202A patent/JP2013256541A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2348488C (en) | 2011-03-01 |
US6773916B1 (en) | 2004-08-10 |
DE69932084D1 (de) | 2006-08-03 |
WO2000040262A1 (en) | 2000-07-13 |
CA2348488A1 (en) | 2000-07-13 |
JP2013256541A (ja) | 2013-12-26 |
NZ511219A (en) | 2003-05-30 |
EP1140170A4 (en) | 2002-04-10 |
EP1140170A1 (en) | 2001-10-10 |
DE69932084T2 (de) | 2007-06-28 |
ATE330631T1 (de) | 2006-07-15 |
JP5483789B2 (ja) | 2014-05-07 |
JP5703039B2 (ja) | 2015-04-15 |
JP2002534394A (ja) | 2002-10-15 |
JP2011084578A (ja) | 2011-04-28 |
EP1140170B1 (en) | 2006-06-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1140170T3 (da) | Antistoffragmenter til topisk behandling af öjensygdomme | |
BRPI0413489A (pt) | composições polipeptìdicas de ligação a cd20 | |
CY1118429T1 (el) | Αντισωμα συνδεσης αλφα4βητα7 ιντεγκρινης και η χρηση αυτου εις τη θεραπευτικη αγωγη της φλεγμονωδους νοσου του εντερου | |
DK2853272T3 (da) | Terapeutisk anvendelse af anti-CS1-antistoffer | |
KR101155294B1 (ko) | 면역특이적으로 BLyS에 결합하는 항체 | |
BRPI0418695A (pt) | uso terapêutico de anticorpos anti-cs1 | |
BRPI0412245A (pt) | anticorpos de rg1 e usos destes | |
UA111707C2 (uk) | Застосування виділеного анти-tnf-альфа антитіла людини | |
ES2120416T3 (es) | Inhibidores del crecimiento tumoral derivados de tejidos, metodos de preparacion y usos de dichos inhibidores. | |
ATE470676T1 (de) | Anti-vegf-2 antikörper | |
BR0315157A (pt) | Métodos de tratar doença de alzheimer empregando-se anticorpos direcionados contra peptìdeo beta amilóide e composições deste | |
EA200101064A1 (ru) | Лечение раковых заболеваний путем комбинированного введения доцетаксела с рекомбинантными гуманизированными моноклональными анти-her2 антителами | |
EA200602015A1 (ru) | Гуманизированные антитела, распознающие бета-амилоидный пептид | |
CY1109817T1 (el) | Ολιγο-βητα-(1,3)-γλυκανη και μονοκλωνικα αντισωματα εναντιον καρκινου | |
BR0212907A (pt) | Métodos para tratamento ou prevenção de inflamação vascular usando inibidor(es) da absorção de esteróis | |
EA200401081A1 (ru) | Fab-фрагменты моноклонального антитела человека, направленные против гликопротеина e2 hcv и обладающие нейтрализующей активностью in vitro | |
BR0210648A (pt) | Variante de uma molécula imunointerativa, anticorpo monoclonal, forma disimunizada de anticorpo monoclonal 3b6, método para a geração de um anticorpo monoclonal desimunizado, molécula de anticorpo desimunizada, anticorpo desimunizado, anticorpo monoclonal de murino variante 3b6 desimunizado, variante de um anticorpo monoclonal de murino 3b6 desimunizado para uso em humanos, método para a detecção de um coágulo sanguìneo em um paciente humano, método para a detecção de um coágulo sanguìneo ou de um seu fragmento de ligação a antìgeno, método para a facilitação da dissolução ou da remoção de um coágulo sanguìneo em um humano, uso de um anticorpo monoclonal derivado de murino variante, e, conjugado | |
CL2023000099A1 (es) | Tratamiento de enfermedades inflamatorias con anticuerpos anti-factor tisular | |
DK1411962T3 (da) | Terapi for pancreacancer med monoklonalt stof | |
CY1115003T1 (el) | Θεραπευτικη χρηση των αντισωματων αντι-cs1 | |
NO943653L (no) | Rekombinante, humane HIV-nöytraliserende monoklonale antistoffer for forebyggelse og behandling av HIV-infeksjon | |
EA202192865A1 (ru) | Лечение головной боли с использованием антител к cgrp | |
WO2003097082A3 (en) | Treatment of crohn's disease or psoriasis using anti-inteferon gamma antibodies | |
DE69829995D1 (de) | Multivalente rekombinante antikörper zur behandlung von hrv infektionen | |
BR9910589A (pt) | Anticorpo humanizado, processo para produzir anticorpo humanizado vtm1-1, composição farmacêutica, e, processo para tratar um paciente sofrendo ou em risco dos efeitos tóxicos de uma verotoxina, e, linhagem de célula |