DK1127877T3 - 5-cyano-10-hydroxy-10,11-dihydro-5H-bibenz[b,f]azepin, fremgangsmåder til dets fremstilling og til dets omdannelse til 5-carbomoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin eller til 5-carbomoyl-5H-dibenz[b,f]azepin - Google Patents

5-cyano-10-hydroxy-10,11-dihydro-5H-bibenz[b,f]azepin, fremgangsmåder til dets fremstilling og til dets omdannelse til 5-carbomoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin eller til 5-carbomoyl-5H-dibenz[b,f]azepin

Info

Publication number
DK1127877T3
DK1127877T3 DK01103475T DK01103475T DK1127877T3 DK 1127877 T3 DK1127877 T3 DK 1127877T3 DK 01103475 T DK01103475 T DK 01103475T DK 01103475 T DK01103475 T DK 01103475T DK 1127877 T3 DK1127877 T3 DK 1127877T3
Authority
DK
Denmark
Prior art keywords
azepine
carbomoyl
dibenz
dihydro
preparation
Prior art date
Application number
DK01103475T
Other languages
English (en)
Inventor
Attilio Citterio
Gabriele Breviglieri
Giacomo Bruno
Original Assignee
Farchemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farchemia Srl filed Critical Farchemia Srl
Application granted granted Critical
Publication of DK1127877T3 publication Critical patent/DK1127877T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
DK01103475T 2000-02-25 2001-02-14 5-cyano-10-hydroxy-10,11-dihydro-5H-bibenz[b,f]azepin, fremgangsmåder til dets fremstilling og til dets omdannelse til 5-carbomoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin eller til 5-carbomoyl-5H-dibenz[b,f]azepin DK1127877T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI000345A IT1317854B1 (it) 2000-02-25 2000-02-25 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in

Publications (1)

Publication Number Publication Date
DK1127877T3 true DK1127877T3 (da) 2004-10-11

Family

ID=11444177

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01103475T DK1127877T3 (da) 2000-02-25 2001-02-14 5-cyano-10-hydroxy-10,11-dihydro-5H-bibenz[b,f]azepin, fremgangsmåder til dets fremstilling og til dets omdannelse til 5-carbomoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin eller til 5-carbomoyl-5H-dibenz[b,f]azepin

Country Status (9)

Country Link
US (1) US6384217B1 (da)
EP (1) EP1127877B1 (da)
AT (1) ATE268325T1 (da)
DE (1) DE60103568T2 (da)
DK (1) DK1127877T3 (da)
ES (1) ES2219447T3 (da)
IT (1) IT1317854B1 (da)
PT (1) PT1127877E (da)
SI (1) SI1127877T1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20042230A1 (it) 2004-11-19 2005-02-19 Farchemia Srl Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
ITMI20042291A1 (it) * 2004-11-26 2005-02-26 Farchema S R L Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
CA2658675A1 (en) * 2006-07-24 2008-01-31 Jubilant Organosys Limited Process for producing 10-oxo-10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
CN110563652B (zh) * 2018-06-06 2021-01-22 新发药业有限公司 一种中间体化合物、卡马西平及其衍生物及奥卡西平及其衍生物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE597793A (fr) * 1960-12-05 1961-06-05 Geigy Ag J R Nouveaux dérivés de l'azépine et leur préparation.
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FI75561C (fi) * 1979-10-30 1988-07-11 Ciba Geigy Ag Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter.
JPS5681565A (en) * 1979-10-30 1981-07-03 Ciba Geigy Ag Manufacture of nnheterocyclic compound
DD265759A3 (de) * 1987-05-25 1989-03-15 Dresden Arzneimittel Verfahren zur herstellung von 5-carbamoyl-5h-dibenz[b,f]azepin
JP4038834B2 (ja) * 1997-06-13 2008-01-30 東レ株式会社 発光素子

Also Published As

Publication number Publication date
EP1127877B1 (en) 2004-06-02
SI1127877T1 (en) 2004-08-31
IT1317854B1 (it) 2003-07-15
ITMI20000345A0 (it) 2000-02-25
ITMI20000345A1 (it) 2001-08-25
EP1127877A2 (en) 2001-08-29
ATE268325T1 (de) 2004-06-15
PT1127877E (pt) 2004-08-31
DE60103568T2 (de) 2004-09-30
EP1127877A3 (en) 2002-11-27
US6384217B1 (en) 2002-05-07
ES2219447T3 (es) 2004-12-01
DE60103568D1 (de) 2004-07-08

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