DE60103568D1 - 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepin, Verfahren zu seiner Herstellung und zu seiner Umwandlung zum 5-Carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin oder zum 5-Carbamoyl-5H-dibenz[b,f]azepin - Google Patents

5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepin, Verfahren zu seiner Herstellung und zu seiner Umwandlung zum 5-Carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin oder zum 5-Carbamoyl-5H-dibenz[b,f]azepin

Info

Publication number
DE60103568D1
DE60103568D1 DE60103568T DE60103568T DE60103568D1 DE 60103568 D1 DE60103568 D1 DE 60103568D1 DE 60103568 T DE60103568 T DE 60103568T DE 60103568 T DE60103568 T DE 60103568T DE 60103568 D1 DE60103568 D1 DE 60103568D1
Authority
DE
Germany
Prior art keywords
azepine
dibenz
carbamoyl
dihydro
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60103568T
Other languages
English (en)
Other versions
DE60103568T2 (de
Inventor
Attilio Citterio
Gabriele Breviglieri
Giacomo Bruno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Farchemia SpA
Original Assignee
Farchemia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farchemia SpA filed Critical Farchemia SpA
Application granted granted Critical
Publication of DE60103568D1 publication Critical patent/DE60103568D1/de
Publication of DE60103568T2 publication Critical patent/DE60103568T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
DE60103568T 2000-02-25 2001-02-14 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepin, Verfahren zu seiner Herstellung für die Umwandlung in 5-Carbamoyl-10-oxo-10,11-dihydro-5H-dibenz [b,f]azepin oder in 5-Carbamoyl-5H-dibenz[b,f]azepin Expired - Lifetime DE60103568T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI000345A IT1317854B1 (it) 2000-02-25 2000-02-25 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in
ITMI000345 2000-06-05

Publications (2)

Publication Number Publication Date
DE60103568D1 true DE60103568D1 (de) 2004-07-08
DE60103568T2 DE60103568T2 (de) 2004-09-30

Family

ID=11444177

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60103568T Expired - Lifetime DE60103568T2 (de) 2000-02-25 2001-02-14 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepin, Verfahren zu seiner Herstellung für die Umwandlung in 5-Carbamoyl-10-oxo-10,11-dihydro-5H-dibenz [b,f]azepin oder in 5-Carbamoyl-5H-dibenz[b,f]azepin

Country Status (9)

Country Link
US (1) US6384217B1 (de)
EP (1) EP1127877B1 (de)
AT (1) ATE268325T1 (de)
DE (1) DE60103568T2 (de)
DK (1) DK1127877T3 (de)
ES (1) ES2219447T3 (de)
IT (1) IT1317854B1 (de)
PT (1) PT1127877E (de)
SI (1) SI1127877T1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20042230A1 (it) * 2004-11-19 2005-02-19 Farchemia Srl Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
ITMI20042291A1 (it) 2004-11-26 2005-02-26 Farchema S R L Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
WO2008012837A1 (en) * 2006-07-24 2008-01-31 Jubilant Organosys Limited Process for producing 10-oxo-l10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
CN110563652B (zh) * 2018-06-06 2021-01-22 新发药业有限公司 一种中间体化合物、卡马西平及其衍生物及奥卡西平及其衍生物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE597793A (fr) * 1960-12-05 1961-06-05 Geigy Ag J R Nouveaux dérivés de l'azépine et leur préparation.
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FI75561C (fi) * 1979-10-30 1988-07-11 Ciba Geigy Ag Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter.
JPS5681565A (en) * 1979-10-30 1981-07-03 Ciba Geigy Ag Manufacture of nnheterocyclic compound
DD265759A3 (de) * 1987-05-25 1989-03-15 Dresden Arzneimittel Verfahren zur herstellung von 5-carbamoyl-5h-dibenz[b,f]azepin
JP4038834B2 (ja) * 1997-06-13 2008-01-30 東レ株式会社 発光素子

Also Published As

Publication number Publication date
EP1127877A2 (de) 2001-08-29
DE60103568T2 (de) 2004-09-30
IT1317854B1 (it) 2003-07-15
SI1127877T1 (en) 2004-08-31
EP1127877A3 (de) 2002-11-27
PT1127877E (pt) 2004-08-31
DK1127877T3 (da) 2004-10-11
ITMI20000345A1 (it) 2001-08-25
ES2219447T3 (es) 2004-12-01
EP1127877B1 (de) 2004-06-02
ATE268325T1 (de) 2004-06-15
ITMI20000345A0 (it) 2000-02-25
US6384217B1 (en) 2002-05-07

Similar Documents

Publication Publication Date Title
ATE260343T1 (de) Bernsteinsäure herstellung und reinigung
TR200002298A3 (tr) 1,2,4,5- Tetrahidro-Benzo [D] azepinler
DE60008862D1 (de) Thienopyrimidin verbindungen, ihre herstellung und verwendung
ATE239751T1 (de) 9-hydrazon- und 9-azynerythromycinderivate und verfahren zu deren herstellung
EE200100574A (et) Uued ühendid, nende valmistamise meetod ning kasutamine
ATE349430T1 (de) Verfahren zur herstellung von (s)-(+)- und (r)-(- )-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepin 5-carboxamid
DE60111904D1 (de) Biosensor und verfahren zu dessen herstellung
ZA200102642B (en) Process for the preparation of 11-amino-3-chloro-6, 11-dihydro-5, 5-dioxo-6-methyl-dibenzo [C, F] [1, 2] Thiazepine and application to the synthesis of tianeptine.
DE60043966D1 (de) Hochermüdungsfester Stahldraht und Verfahren zu dessen Herstellung
DE60209537D1 (de) Neue kristalline formen von meloxicam, deren herstellung und verfahren zu deren umwandlung ineinander
DE50206559D1 (de) Amorphe organische 1,3,2-dioxaborinluminophore, verfahren zu deren herstellung und verwendung davon
ATE251170T1 (de) Titanverbindungen, deren herstellung und verwendung
DE60111467D1 (de) Hohles faseriges organisches Nanorohr und Verfahren zu seiner Herstellung
IL198455A (en) Method for Preparing 10 Oxo 10,11 Hydrogen Dibenz [f, b] Azine-5-Carboxamide
DE60227517D1 (de) Verfahren zur herstellung von 10,11 dihydro 10 hydroxy 5h-dibenz/b,f/azepin-5-carbonsäureamid und 10,11 dihydro 10 oxo-5h-dibenz/b,f/azepin-5 carbonsäureamid
NO324949B1 (no) Fremgangsmate for fremstilling av dibenzo[b,f]azepiner
DE60103568D1 (de) 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepin, Verfahren zu seiner Herstellung und zu seiner Umwandlung zum 5-Carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin oder zum 5-Carbamoyl-5H-dibenz[b,f]azepin
ATE301645T1 (de) Polycyclische thiazolidin-2-yliden amine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE60045430D1 (de) Kohlenwasserstoffsensor und Methode zu dessen Herstellung
EE200100573A (et) Uued ühendid, nende valmistamise meetod ning kasutamine
ATE485271T1 (de) Antihistaminische piperidinderivate und zwischenprodukte zu ihrer herstellung
DE59902408D1 (de) Biphenylsulfonylcyanamide, verfahren zu ihrer herstellung und ihre verwendung als medikament
ID30551A (id) Proses konversi hidrokarbon
ATE224890T1 (de) Substituierte 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin- 0-ole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE60216519D1 (de) Verfahren zur herstellung von 6-aminomethyl-6,11-dihydro-5h-dibenz(b,e)azepin

Legal Events

Date Code Title Description
8364 No opposition during term of opposition