ITMI20000345A0 - 5-ciano-10-idrossi-10 11-diidro-5h-dibenz[b,f]azepina e procedimenti per la sua preparazione e per la sua conversione in 5-carbamoil-10-oxo- - Google Patents

5-ciano-10-idrossi-10 11-diidro-5h-dibenz[b,f]azepina e procedimenti per la sua preparazione e per la sua conversione in 5-carbamoil-10-oxo-

Info

Publication number
ITMI20000345A0
ITMI20000345A0 IT2000MI000345A ITMI20000345A ITMI20000345A0 IT MI20000345 A0 ITMI20000345 A0 IT MI20000345A0 IT 2000MI000345 A IT2000MI000345 A IT 2000MI000345A IT MI20000345 A ITMI20000345 A IT MI20000345A IT MI20000345 A0 ITMI20000345 A0 IT MI20000345A0
Authority
IT
Italy
Prior art keywords
carbamoil
dibenz
azepine
cyan
dihydro
Prior art date
Application number
IT2000MI000345A
Other languages
English (en)
Inventor
Gabriele Breviglieri
Attilio Citterio
Original Assignee
Farchemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farchemia Srl filed Critical Farchemia Srl
Publication of ITMI20000345A0 publication Critical patent/ITMI20000345A0/it
Priority to IT2000MI000345A priority Critical patent/IT1317854B1/it
Priority to SI200130114T priority patent/SI1127877T1/xx
Priority to ES01103475T priority patent/ES2219447T3/es
Priority to DE60103568T priority patent/DE60103568T2/de
Priority to PT01103475T priority patent/PT1127877E/pt
Priority to DK01103475T priority patent/DK1127877T3/da
Priority to AT01103475T priority patent/ATE268325T1/de
Priority to EP01103475A priority patent/EP1127877B1/en
Priority to US09/788,048 priority patent/US6384217B1/en
Publication of ITMI20000345A1 publication Critical patent/ITMI20000345A1/it
Application granted granted Critical
Publication of IT1317854B1 publication Critical patent/IT1317854B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
IT2000MI000345A 2000-02-25 2000-02-25 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in IT1317854B1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT2000MI000345A IT1317854B1 (it) 2000-02-25 2000-02-25 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in
PT01103475T PT1127877E (pt) 2000-02-25 2001-02-14 5-ciano-10-hidroxi-10,11-di-hidro-5h-dibenzo¬b,f|azepina os processos para a sua preparacao e para a sua conversao em 5-carbamoil-10-oxo-10,11-di-hidro-5h-dibenzo¬b,f|azepina ou em 5-carbamoil-5h-dibenzo¬b,f|azepina
ES01103475T ES2219447T3 (es) 2000-02-25 2001-02-14 5-ciano-10-hidroxi-10,11-dihidro-5h-dibenz(b,f)azepina, procedimientos para su preparacion y para su conversion en 5-carbamoil-10-oxo-10,11dihidro-5h-dibenz(b,f)azepina o en 5-carbamoil-5h-dibenz(b,f)azepina.
DE60103568T DE60103568T2 (de) 2000-02-25 2001-02-14 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepin, Verfahren zu seiner Herstellung für die Umwandlung in 5-Carbamoyl-10-oxo-10,11-dihydro-5H-dibenz [b,f]azepin oder in 5-Carbamoyl-5H-dibenz[b,f]azepin
SI200130114T SI1127877T1 (en) 2000-02-25 2001-02-14 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz(b,f)azepine, processes for its preparation and for its conversion into 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz(b,f)azepine or into 5-carbamoyl-5H-dibenz(b,f)azepine
DK01103475T DK1127877T3 (da) 2000-02-25 2001-02-14 5-cyano-10-hydroxy-10,11-dihydro-5H-bibenz[b,f]azepin, fremgangsmåder til dets fremstilling og til dets omdannelse til 5-carbomoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepin eller til 5-carbomoyl-5H-dibenz[b,f]azepin
AT01103475T ATE268325T1 (de) 2000-02-25 2001-02-14 5-cyano-10-hydroxy-10,11-dihydro-5h-dibenz(b, f)azepin, verfahren zu seiner herstellung und zu seiner umwandlung zum 5-carbamoyl-10-oxo-10,11- dihydro-5h-dibenz(b,f)azepin oder zum 5-carbamoyl-5h-dibenz(b,f)azepin
EP01103475A EP1127877B1 (en) 2000-02-25 2001-02-14 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine, processes for its preparation and for its conversion into 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine or into 5-carbamoyl-5H-dibenz[b,f]azepine
US09/788,048 US6384217B1 (en) 2000-02-25 2001-02-17 5-cyano-10-hydroxy-10,11-dihydro-5h-dibenz[b,f]azepine, the processes for its preparation and for its conversion into 5-carbamoyl-10-oxo-10, 11-dihydro-5h-dibenz[b,f]azepine or into 5-carbamoyl-5h-dibenz[b,f]azepine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI000345A IT1317854B1 (it) 2000-02-25 2000-02-25 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in

Publications (3)

Publication Number Publication Date
ITMI20000345A0 true ITMI20000345A0 (it) 2000-02-25
ITMI20000345A1 ITMI20000345A1 (it) 2001-08-25
IT1317854B1 IT1317854B1 (it) 2003-07-15

Family

ID=11444177

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000MI000345A IT1317854B1 (it) 2000-02-25 2000-02-25 5-ciano-10-idrossi-10,11-diidro-5h-dibenz(b,f)azepina e procedimentiper la sua preparazione e per la sua conversione in

Country Status (9)

Country Link
US (1) US6384217B1 (it)
EP (1) EP1127877B1 (it)
AT (1) ATE268325T1 (it)
DE (1) DE60103568T2 (it)
DK (1) DK1127877T3 (it)
ES (1) ES2219447T3 (it)
IT (1) IT1317854B1 (it)
PT (1) PT1127877E (it)
SI (1) SI1127877T1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20042230A1 (it) 2004-11-19 2005-02-19 Farchemia Srl Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
ITMI20042291A1 (it) * 2004-11-26 2005-02-26 Farchema S R L Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
CA2658675A1 (en) * 2006-07-24 2008-01-31 Jubilant Organosys Limited Process for producing 10-oxo-10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
CN110563652B (zh) * 2018-06-06 2021-01-22 新发药业有限公司 一种中间体化合物、卡马西平及其衍生物及奥卡西平及其衍生物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE597793A (fr) * 1960-12-05 1961-06-05 Geigy Ag J R Nouveaux dérivés de l'azépine et leur préparation.
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FI75561C (fi) * 1979-10-30 1988-07-11 Ciba Geigy Ag Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter.
JPS5681565A (en) * 1979-10-30 1981-07-03 Ciba Geigy Ag Manufacture of nnheterocyclic compound
DD265759A3 (de) * 1987-05-25 1989-03-15 Dresden Arzneimittel Verfahren zur herstellung von 5-carbamoyl-5h-dibenz[b,f]azepin
JP4038834B2 (ja) * 1997-06-13 2008-01-30 東レ株式会社 発光素子

Also Published As

Publication number Publication date
EP1127877B1 (en) 2004-06-02
SI1127877T1 (en) 2004-08-31
IT1317854B1 (it) 2003-07-15
ITMI20000345A1 (it) 2001-08-25
EP1127877A2 (en) 2001-08-29
ATE268325T1 (de) 2004-06-15
PT1127877E (pt) 2004-08-31
DK1127877T3 (da) 2004-10-11
DE60103568T2 (de) 2004-09-30
EP1127877A3 (en) 2002-11-27
US6384217B1 (en) 2002-05-07
ES2219447T3 (es) 2004-12-01
DE60103568D1 (de) 2004-07-08

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