DK1117685T3 - Behandling af inflammatorisk sygdom - Google Patents

Behandling af inflammatorisk sygdom

Info

Publication number
DK1117685T3
DK1117685T3 DK99949169T DK99949169T DK1117685T3 DK 1117685 T3 DK1117685 T3 DK 1117685T3 DK 99949169 T DK99949169 T DK 99949169T DK 99949169 T DK99949169 T DK 99949169T DK 1117685 T3 DK1117685 T3 DK 1117685T3
Authority
DK
Denmark
Prior art keywords
grp78
bip
protein
treatment
fragment
Prior art date
Application number
DK99949169T
Other languages
Danish (da)
English (en)
Inventor
Gabriel Stavros Panayi
Valerie Mary Corrigall
Mark Duncan Bodman-Smith
Mark Stewart Fife
Jeremy Shaun Lanchbury
Original Assignee
King S College London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by King S College London filed Critical King S College London
Application granted granted Critical
Publication of DK1117685T3 publication Critical patent/DK1117685T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK99949169T 1998-10-09 1999-10-08 Behandling af inflammatorisk sygdom DK1117685T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9822115.3A GB9822115D0 (en) 1998-10-09 1998-10-09 Treatment of inflammatory disease
PCT/GB1999/003316 WO2000021995A1 (en) 1998-10-09 1999-10-08 Treatment of inflammatory disease

Publications (1)

Publication Number Publication Date
DK1117685T3 true DK1117685T3 (da) 2007-03-05

Family

ID=10840332

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99949169T DK1117685T3 (da) 1998-10-09 1999-10-08 Behandling af inflammatorisk sygdom

Country Status (12)

Country Link
US (1) US6995240B1 (de)
EP (1) EP1117685B1 (de)
JP (1) JP4435422B2 (de)
CN (1) CN1253470C (de)
AT (1) ATE347561T1 (de)
AU (1) AU754888B2 (de)
CA (1) CA2344590C (de)
DE (1) DE69934324T2 (de)
DK (1) DK1117685T3 (de)
ES (1) ES2277449T3 (de)
GB (1) GB9822115D0 (de)
WO (1) WO2000021995A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094597B1 (en) * 1994-05-20 2006-08-22 The Regents Of The University Of California Vaccine compositions and methods useful in inducing immune protection against arthritogenic peptides involved in the pathogenesis of rheumatoid arthritis
GB0106161D0 (en) * 2001-03-13 2001-05-02 King S College London Immunomodulators
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
DE10210427A1 (de) * 2002-03-09 2003-10-09 Hans Konrad Mueller-Hermelink Humaner monoklonaler Antikörper
EP2322559A3 (de) * 2002-07-04 2011-08-03 Patrys Limited Neoplasma-spezifische Antikörper und deren Verwendungen
DE10311248A1 (de) * 2003-03-14 2004-09-30 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper
NZ577824A (en) * 2003-11-12 2010-10-29 Patrys Ltd Methods of identifying neoplasm-specific antibodies and uses thereof
EP1531162A1 (de) * 2003-11-14 2005-05-18 Heinz Vollmers Antikörper SAM-6, der spezifisch von Adenocarzinom ist, und dessen Verwendungen
DE10353175A1 (de) * 2003-11-14 2005-06-16 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper mit fettsenkender Wirkung
DE102004015179A1 (de) * 2004-03-25 2005-10-13 Oncomab Gmbh Antigen des PM-2 Antikörpers und dessen Verwendung
EP1874331B1 (de) 2005-04-19 2014-09-03 Kings College London Verwendung von bip gegen knochenverlust und osteoporose
JP2010510772A (ja) * 2006-11-27 2010-04-08 パトリス リミテッド 新生細胞における新規なグリコシル化ペプチド標的
KR20100128281A (ko) * 2008-01-23 2010-12-07 릭스하스피탈렛 바이오마커 와이케이엘-40의 수준을 측정함으로써 발견되는 생존 예후에 따른 심혈관계 질환에 걸린 개체들의 분류 방법
AU2010210312A1 (en) * 2009-02-09 2011-08-04 Patrys Limited SAM-6 variants, target and methods of use
JP2011116719A (ja) * 2009-12-07 2011-06-16 Univ Of Tokyo Ｈｌａ−ｄｒ４エピトープの同定と、関節炎治療への応用
GB201603263D0 (en) 2016-02-25 2016-04-13 King S College London Biomarkers for response to bip (rasolvir)
JP2021528100A (ja) * 2018-06-13 2021-10-21 イミューン レギュレーション リミテッド 抗炎症特性を有する新規タンパク質
WO2023187422A1 (en) 2022-03-31 2023-10-05 Revolo Biotherapeutics Limited Compositions and their use in methods for treating intestinal inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348945A (en) * 1990-04-06 1994-09-20 Wake Forest University Method of treatment with hsp70
US5188964A (en) * 1990-04-12 1993-02-23 Board Of Regents, The University Of Texas System Method and kit for the prognostication of breast cancer patient via heat shock/stress protein determination
DK0663010T3 (da) * 1992-10-02 2000-11-13 Res Corp Technologies Inc Fremgangsmåde til forøgelse af sekretion af overudtrykte proteiner
DE19744132A1 (de) * 1997-10-01 1999-04-22 Stefan Dr Blaes Anti-Heavy Chain Binding Protein-Antikörper (Anti-BiP-Antikörper) bei rheumatoider Arthritis sowie Verfahren und Testkits zu ihrer Bestimmung in Körperflüssigkeiten
DE19817557A1 (de) 1998-04-09 1999-10-21 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Ovartumorgewebe

Also Published As

Publication number Publication date
DE69934324D1 (de) 2007-01-18
ATE347561T1 (de) 2006-12-15
US6995240B1 (en) 2006-02-07
GB9822115D0 (en) 1998-12-02
DE69934324T2 (de) 2007-07-05
WO2000021995A1 (en) 2000-04-20
CA2344590C (en) 2011-05-10
CA2344590A1 (en) 2000-04-20
AU754888B2 (en) 2002-11-28
JP4435422B2 (ja) 2010-03-17
ES2277449T3 (es) 2007-07-01
EP1117685B1 (de) 2006-12-06
AU6215499A (en) 2000-05-01
CN1253470C (zh) 2006-04-26
EP1117685A1 (de) 2001-07-25
JP2003523167A (ja) 2003-08-05
CN1322213A (zh) 2001-11-14

Similar Documents

Publication Publication Date Title
DK1117685T3 (da) Behandling af inflammatorisk sygdom
DK1092155T3 (da) Fremgangsmåde til tidlig diagnose af carcinomer
DE69823985D1 (de) Nachweis der krankheitsbedingten konformation eines proteins
CY1112101T1 (el) Νευροτροφικοι παραγοντες
PT738390E (pt) Substitutos para alvos e paineis de referencia melhorados
DE69228701D1 (de) Fragmente von Prion Proteinen.
ES2137354T3 (es) Moleculas de anticuerpo anti-vla4 recombinante.
ES8800435A1 (es) Un metodo de inmunoensayo.
ATE232300T1 (de) Charakterisierung von polypeptiden durch spaltung und massenspektrometrie
DE69821246D1 (de) Testverfahren für collagenpeptid
GB8925590D0 (en) Monoclonal antibodies
DK0948604T3 (da) Screeningsmetoder for forbindelser som binder til PYK2-polypeptidet
DK0455707T3 (da) Blodkoagulationsfaktor betaXIIa monoklonalt antistof og immunassay
GR3031607T3 (en) Selective system scan for multizone radiotelephone subscriber units.
PT865609E (pt) Processos para o diagnostico e terapia de carcinomas do epitelio escamoso
ATE312914T1 (de) Rdgb-proteine
DK0583352T3 (da) hGPIIB fragmenter og deres anvendelse i in vitro metoder til bestemmelse af in vivo thrombotiske tilstande
DK1171157T3 (da) Anvendelse af glucose-6-phosphat-isomerase og antistoffer derimod til diagnosticering og behandling af arthritis, og test for anti-arthritis-forbindelser
EP1079230A4 (de) Verfahren zum screenen einer die oligomerisierung von rezeptorproteinmolekülen fördernden substanz
BR0214288A (pt) Anticorpos monoclonais especìficos para tumor, ácidos nucléicos que codificam tais anticorpos e método para redução de proliferação de células neoplásicas
DE60221698D1 (de) Nukleares protein "shoca" - eine komponente des wnt signaltransduktionsweges
DE69333683D1 (de) Antikörper-testbesteck zur bestimmung von amylin
CY1116268T1 (el) Αντισωματα που δεσμευονται με κυτταροσυνδετο ca 125/0772ρ και μεθοδοι χρησεις αυτων
ES2088820B1 (es) Anticuerpos monoclonales antineumolisina.