DE69934324D1 - Behandlung von entzündungskrankheiten - Google Patents

Behandlung von entzündungskrankheiten

Info

Publication number
DE69934324D1
DE69934324D1 DE69934324T DE69934324T DE69934324D1 DE 69934324 D1 DE69934324 D1 DE 69934324D1 DE 69934324 T DE69934324 T DE 69934324T DE 69934324 T DE69934324 T DE 69934324T DE 69934324 D1 DE69934324 D1 DE 69934324D1
Authority
DE
Germany
Prior art keywords
grp78
bip
protein
treatment
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69934324T
Other languages
English (en)
Other versions
DE69934324T2 (de
Inventor
Stavros Panayi
Mary Corrigall
Duncan Bodman-Smith
Stewart Fife
Shaun Lanchbury
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kings College London
Original Assignee
Kings College London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kings College London filed Critical Kings College London
Publication of DE69934324D1 publication Critical patent/DE69934324D1/de
Application granted granted Critical
Publication of DE69934324T2 publication Critical patent/DE69934324T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69934324T 1998-10-09 1999-10-08 Behandlung von entzündungskrankheiten Expired - Lifetime DE69934324T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9822115 1998-10-09
GBGB9822115.3A GB9822115D0 (en) 1998-10-09 1998-10-09 Treatment of inflammatory disease
PCT/GB1999/003316 WO2000021995A1 (en) 1998-10-09 1999-10-08 Treatment of inflammatory disease

Publications (2)

Publication Number Publication Date
DE69934324D1 true DE69934324D1 (de) 2007-01-18
DE69934324T2 DE69934324T2 (de) 2007-07-05

Family

ID=10840332

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69934324T Expired - Lifetime DE69934324T2 (de) 1998-10-09 1999-10-08 Behandlung von entzündungskrankheiten

Country Status (12)

Country Link
US (1) US6995240B1 (de)
EP (1) EP1117685B1 (de)
JP (1) JP4435422B2 (de)
CN (1) CN1253470C (de)
AT (1) ATE347561T1 (de)
AU (1) AU754888B2 (de)
CA (1) CA2344590C (de)
DE (1) DE69934324T2 (de)
DK (1) DK1117685T3 (de)
ES (1) ES2277449T3 (de)
GB (1) GB9822115D0 (de)
WO (1) WO2000021995A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094597B1 (en) * 1994-05-20 2006-08-22 The Regents Of The University Of California Vaccine compositions and methods useful in inducing immune protection against arthritogenic peptides involved in the pathogenesis of rheumatoid arthritis
GB0106161D0 (en) * 2001-03-13 2001-05-02 King S College London Immunomodulators
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
DE10210427A1 (de) * 2002-03-09 2003-10-09 Hans Konrad Mueller-Hermelink Humaner monoklonaler Antikörper
WO2004005351A2 (en) * 2002-07-04 2004-01-15 Oncomab Gmbh Neoplasm specific antibodies and uses thereof
DE10311248A1 (de) * 2003-03-14 2004-09-30 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper
JP2007521020A (ja) * 2003-11-12 2007-08-02 オンコマブ・ゲーエムベーハー 新生物特異的抗体を同定する方法及びその使用
DE10353175A1 (de) 2003-11-14 2005-06-16 Müller-Hermelink, Hans Konrad, Prof. Dr. Humaner monoklonaler Antikörper mit fettsenkender Wirkung
EP1531162A1 (de) 2003-11-14 2005-05-18 Heinz Vollmers Antikörper SAM-6, der spezifisch von Adenocarzinom ist, und dessen Verwendungen
DE102004015179A1 (de) * 2004-03-25 2005-10-13 Oncomab Gmbh Antigen des PM-2 Antikörpers und dessen Verwendung
EP1874331B1 (de) 2005-04-19 2014-09-03 Kings College London Verwendung von bip gegen knochenverlust und osteoporose
EP2101813B1 (de) * 2006-11-27 2014-04-02 Patrys Limited Neues glykosyliertes zielpeptid in neoplastischen zellen
CN101952721A (zh) * 2008-01-23 2011-01-19 里格舒斯匹塔里特医院 根据测量生物标记ykl-40的水平所发现的生存预后,对患有心血管疾病的个体的分类
AU2010210312A1 (en) * 2009-02-09 2011-08-04 Patrys Limited SAM-6 variants, target and methods of use
JP2011116719A (ja) * 2009-12-07 2011-06-16 Univ Of Tokyo Ｈｌａ−ｄｒ４エピトープの同定と、関節炎治療への応用
GB201603263D0 (en) 2016-02-25 2016-04-13 King S College London Biomarkers for response to bip (rasolvir)
BR112020025398A2 (pt) * 2018-06-13 2021-04-06 Immune Regulation Limited Proteína com propriedades anti-inflamatórias
WO2023187422A1 (en) 2022-03-31 2023-10-05 Revolo Biotherapeutics Limited Compositions and their use in methods for treating intestinal inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348945A (en) * 1990-04-06 1994-09-20 Wake Forest University Method of treatment with hsp70
US5188964A (en) * 1990-04-12 1993-02-23 Board Of Regents, The University Of Texas System Method and kit for the prognostication of breast cancer patient via heat shock/stress protein determination
DE69329202T2 (de) 1992-10-02 2001-03-29 Res Corp Technologies Inc Methoden der erhöhung der sekretion von überexpremierten proteinen
DE19744132A1 (de) 1997-10-01 1999-04-22 Stefan Dr Blaes Anti-Heavy Chain Binding Protein-Antikörper (Anti-BiP-Antikörper) bei rheumatoider Arthritis sowie Verfahren und Testkits zu ihrer Bestimmung in Körperflüssigkeiten
DE19817557A1 (de) 1998-04-09 1999-10-21 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Ovartumorgewebe

Also Published As

Publication number Publication date
DK1117685T3 (da) 2007-03-05
CN1253470C (zh) 2006-04-26
JP4435422B2 (ja) 2010-03-17
WO2000021995A1 (en) 2000-04-20
JP2003523167A (ja) 2003-08-05
AU6215499A (en) 2000-05-01
US6995240B1 (en) 2006-02-07
AU754888B2 (en) 2002-11-28
ES2277449T3 (es) 2007-07-01
CA2344590C (en) 2011-05-10
EP1117685A1 (de) 2001-07-25
CA2344590A1 (en) 2000-04-20
DE69934324T2 (de) 2007-07-05
CN1322213A (zh) 2001-11-14
GB9822115D0 (en) 1998-12-02
ATE347561T1 (de) 2006-12-15
EP1117685B1 (de) 2006-12-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8370 Indication related to discontinuation of the patent is to be deleted