DK1110554T3 - Medicinal præparater til behandling af öjensygdomme - Google Patents

Medicinal præparater til behandling af öjensygdomme

Info

Publication number
DK1110554T3
DK1110554T3 DK99940582T DK99940582T DK1110554T3 DK 1110554 T3 DK1110554 T3 DK 1110554T3 DK 99940582 T DK99940582 T DK 99940582T DK 99940582 T DK99940582 T DK 99940582T DK 1110554 T3 DK1110554 T3 DK 1110554T3
Authority
DK
Denmark
Prior art keywords
eye diseases
medications
treatment
compositions
ocular tension
Prior art date
Application number
DK99940582T
Other languages
English (en)
Inventor
Toichi Abiru
Kazuki Endo
Tomokazu Hosokawa
Miwa Misawa
Takashi Konno
Original Assignee
Yamasa Corp
Toa Eiyo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Corp, Toa Eiyo Ltd filed Critical Yamasa Corp
Application granted granted Critical
Publication of DK1110554T3 publication Critical patent/DK1110554T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
DK99940582T 1998-09-01 1999-08-31 Medicinal præparater til behandling af öjensygdomme DK1110554T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24682698A JP2002173427A (ja) 1998-09-01 1998-09-01 眼疾患治療用医薬組成物

Publications (1)

Publication Number Publication Date
DK1110554T3 true DK1110554T3 (da) 2006-04-10

Family

ID=17154279

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99940582T DK1110554T3 (da) 1998-09-01 1999-08-31 Medicinal præparater til behandling af öjensygdomme

Country Status (11)

Country Link
US (1) US6387889B1 (da)
EP (1) EP1110554B1 (da)
JP (1) JP2002173427A (da)
CN (1) CN1151794C (da)
AT (1) ATE319458T1 (da)
AU (1) AU5446299A (da)
CA (1) CA2342204A1 (da)
DE (1) DE69930271T8 (da)
DK (1) DK1110554T3 (da)
ES (1) ES2259842T3 (da)
WO (1) WO2000012098A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6232297B1 (en) * 1999-02-01 2001-05-15 University Of Virginia Patent Foundation Methods and compositions for treating inflammatory response
AU778870B2 (en) * 1999-02-01 2004-12-23 University Of Virginia Patent Foundation Compositions for treating inflammatory response
US7427606B2 (en) * 1999-02-01 2008-09-23 University Of Virginia Patent Foundation Method to reduce inflammatory response in transplanted tissue
US7378400B2 (en) * 1999-02-01 2008-05-27 University Of Virginia Patent Foundation Method to reduce an inflammatory response from arthritis
ES2173027B2 (es) * 2000-07-06 2005-12-16 Universidad Complutense De Madrid Uso de nucleotidos en el tratamiento del glaucoma y la hipertension ocular.
WO2002020539A1 (fr) * 2000-09-08 2002-03-14 Toa Eiyo Ltd. Derives d'adenosine et leur utilisation
EP1316559B1 (en) * 2000-09-08 2004-11-03 Toa Eiyo Ltd. Adenosine derivatives and use thereof
WO2003029264A2 (en) * 2001-10-01 2003-04-10 University Of Virginia Patent Foundation 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof
ATE381336T1 (de) * 2002-04-10 2008-01-15 Univ Virginia Verwendung von a2a adenosin rezeptor agonisten und anti-pathogene mittel enthaltenden kombinationen zur behandlung von entzündungskrankheiten
EP1740587A4 (en) * 2004-04-02 2009-07-15 Adenosine Therapeutics Llc SELECTIVE ANTAGONISTS OF A2A ADENOSINE RECEPTORS
TWI346109B (en) 2004-04-30 2011-08-01 Otsuka Pharma Co Ltd 4-amino-5-cyanopyrimidine derivatives
WO2006028618A1 (en) * 2004-08-02 2006-03-16 University Of Virginia Patent Foundation 2-polycyclic propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity
WO2006023272A1 (en) * 2004-08-02 2006-03-02 University Of Virginia Patent Foundation 2-polycyclic propynyl adenosine analogs having a2a agonist activity
EP1778712B1 (en) * 2004-08-02 2013-01-30 University Of Virginia Patent Foundation 2-propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity
US8178509B2 (en) * 2006-02-10 2012-05-15 University Of Virginia Patent Foundation Method to treat sickle cell disease
US8188063B2 (en) 2006-06-19 2012-05-29 University Of Virginia Patent Foundation Use of adenosine A2A modulators to treat spinal cord injury
JP2008285478A (ja) * 2007-04-16 2008-11-27 Santen Pharmaceut Co Ltd アデノシンａ２ａ受容体アゴニストを有効成分として含有する緑内障治療剤
US8058259B2 (en) 2007-12-20 2011-11-15 University Of Virginia Patent Foundation Substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters as A2AR agonists
KR20120091049A (ko) * 2009-10-26 2012-08-17 이노텍 파마슈티컬스 코포레이션 안과용 제제 및 이의 제조 방법
EP2879683B1 (en) 2012-08-01 2020-01-22 Lewis and Clark Pharmaceuticals, Inc. N-alkyl-alkynyladenosine-5-uronamide compounds as agonists of a2a receptor
US9822141B2 (en) 2012-08-01 2017-11-21 Lewis And Clark Pharmaceuticals, Inc. N-alkyl 2-(disubstituted)alkynyladenosine-5-uronamides as A2A agonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07106983B2 (ja) * 1987-12-02 1995-11-15 三共株式会社 グリゼオール酸ジエステル誘導体
US5270304A (en) * 1988-11-15 1993-12-14 Yamasa Shoyu Kabushiki Kaisha Therapeutic 2-alkynyl adenosine agent for ischemic diseases of the heart or brain
US5039797A (en) * 1989-10-13 1991-08-13 Yale University 2'-O-(4-benzoyl)benzoyl nucleoside cyclic monophosphate
FR2685918B1 (fr) * 1992-01-08 1995-06-23 Union Pharma Scient Appl Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant.
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista

Also Published As

Publication number Publication date
CN1151794C (zh) 2004-06-02
CA2342204A1 (en) 2000-03-09
ES2259842T3 (es) 2006-10-16
DE69930271T8 (de) 2006-12-28
DE69930271D1 (de) 2006-05-04
EP1110554B1 (en) 2006-03-08
AU5446299A (en) 2000-03-21
US6387889B1 (en) 2002-05-14
ATE319458T1 (de) 2006-03-15
EP1110554A4 (en) 2002-02-06
WO2000012098A1 (fr) 2000-03-09
CN1315862A (zh) 2001-10-03
JP2002173427A (ja) 2002-06-21
EP1110554A1 (en) 2001-06-27
DE69930271T2 (de) 2006-08-24

Similar Documents

Publication Publication Date Title
DK1110554T3 (da) Medicinal præparater til behandling af öjensygdomme
ES2062102T3 (es) Derivados de prostaglandinas para el tratamiento de glaucoma o hipertension ocular.
ATE286384T1 (de) Formulierung mit verzögerter freisetzung enthaltend kollagen und glykosaminoglykan
DE69529670D1 (de) Oxazolidinon derivate und diese enthaltende pharmazeutische zusammensetzungen
ATE426413T1 (de) Verfahren und zusammensetzungen zur behandlung von okularer neovaskularisierung und nervenverletzungen
DE69630325D1 (de) Nervenschutzende für Auge von Säugern unter Anwendung von Kaliumkanalblockern
PT1040830E (pt) Medicamento para doencas neurodegenerativas
DK0799044T3 (da) Topiske oftalmologiske formuleringer indeholdende olopatidin til behandling af allergiske øjensygdomme
BR0210241A (pt) Piranoindazóis e seu uso no tratamento de glaucoma
WO2002009702A3 (en) Use of indole derivatives for the manufacture of a medicament for reducing intracular pressure
ATE111736T1 (de) Okulare hypotensive mittel.
BR0210238A (pt) Novos análogos de aril-amino-propano e seu uso para o tratamento de glaucoma
BR9914128A (pt) Composições antibióticas para tratamento do olho, ouvido e nariz
ATE325610T1 (de) Xanthinderivative zur behandlung von hirnischämie
ATE281464T1 (de) Adenosinderivate und deren verwendung
ATE216889T1 (de) Anwendung von prostagrandin-analogen für die behandlung von glaukome und okuläre hypertension
BR0314419A (pt) Compostos de 5-croman-5-il-etilamina substituìdos, seu uso e composição farmacêutica incluindo-o
DK0871446T3 (da) Anvendelse af eliprodil til fremstilling af et lægemiddel til behandling af ischaemiske sygdomme i nethinden eller den optiske nerve
BR0316775A (pt) Novos análogos de benzopirano e seu uso para o tratamento de glaucoma
ATE204752T1 (de) Therapeutische anwendungen von 2',5'- oligoadenylat-derivaten
AU2001267864A1 (en) Remedial agent for optic nerve disease and the like
MXPA04001255A (es) Uso de compuesto para el tratamiento de condiciones que resultan de lesion al nervio corneo despues de lasik y otras cirugias oculares o trauma.
DE69829227D1 (de) Arzneimittelzusammenstellung zur behandlung des erhöhten augeninnendrucks oder des glaukom
BR0212274A (pt) Uso de estrogênios não-feminilizantes como agentes retinoprotetores para o tratamento de glaucoma
CA2219280A1 (en) Method for reducing intraocular pressure in the mammalian eye by administration of potassium channel blockers