DK1107732T3 - Orale flydende mucoadhæsive præparater - Google Patents
Orale flydende mucoadhæsive præparaterInfo
- Publication number
- DK1107732T3 DK1107732T3 DK99942428T DK99942428T DK1107732T3 DK 1107732 T3 DK1107732 T3 DK 1107732T3 DK 99942428 T DK99942428 T DK 99942428T DK 99942428 T DK99942428 T DK 99942428T DK 1107732 T3 DK1107732 T3 DK 1107732T3
- Authority
- DK
- Denmark
- Prior art keywords
- composition
- safe
- mixtures
- effective amount
- respiratory tract
- Prior art date
Links
- 239000007788 liquid Substances 0.000 title abstract 2
- 230000003232 mucoadhesive effect Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010057190 Respiratory tract infections Diseases 0.000 abstract 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003434 antitussive agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000004927 clay Substances 0.000 abstract 1
- 229910052570 clay Inorganic materials 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000000850 decongestant Substances 0.000 abstract 1
- 229940124581 decongestants Drugs 0.000 abstract 1
- 239000003172 expectorant agent Substances 0.000 abstract 1
- 230000003419 expectorant effect Effects 0.000 abstract 1
- 229940066493 expectorants Drugs 0.000 abstract 1
- 239000004083 gastrointestinal agent Substances 0.000 abstract 1
- 229940125695 gastrointestinal agent Drugs 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 210000002850 nasal mucosa Anatomy 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 abstract 1
- 238000004062 sedimentation Methods 0.000 abstract 1
- 230000001953 sensory effect Effects 0.000 abstract 1
- 239000000377 silicon dioxide Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 239000004408 titanium dioxide Substances 0.000 abstract 1
- 230000001960 triggered effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Anesthesiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Otolaryngology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Developing Agents For Electrophotography (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9764698P | 1998-08-24 | 1998-08-24 | |
| PCT/US1999/019201 WO2000010528A1 (en) | 1998-08-24 | 1999-08-24 | Oral liquid mucoadhesive compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1107732T3 true DK1107732T3 (da) | 2003-03-17 |
Family
ID=22264456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99942428T DK1107732T3 (da) | 1998-08-24 | 1999-08-24 | Orale flydende mucoadhæsive præparater |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20020009478A1 (de) |
| EP (1) | EP1107732B1 (de) |
| JP (1) | JP2002523353A (de) |
| KR (1) | KR20010074834A (de) |
| CN (1) | CN1313754A (de) |
| AT (1) | ATE227978T1 (de) |
| AU (1) | AU753251B2 (de) |
| BR (1) | BR9913148A (de) |
| CA (1) | CA2338480C (de) |
| CO (1) | CO5140074A1 (de) |
| DE (1) | DE69904057T2 (de) |
| DK (1) | DK1107732T3 (de) |
| ES (1) | ES2185395T3 (de) |
| HU (1) | HUP0103217A2 (de) |
| NO (1) | NO20010830D0 (de) |
| PE (1) | PE20000863A1 (de) |
| TR (1) | TR200100569T2 (de) |
| WO (1) | WO2000010528A1 (de) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020009478A1 (en) * | 1998-08-24 | 2002-01-24 | Douglas Joseph Dobrozsi | Oral liquid mucoadhesive compositions |
| EP1997478B1 (de) * | 2001-02-15 | 2013-09-04 | Access Pharmaceuticals, Inc. | Flüssige Formulierungen zur Vorbeugung und Behandlung von Schleimhauterkrankungen und -funktionsstörungen |
| US7544348B2 (en) * | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| ES2195757B1 (es) * | 2001-12-28 | 2005-03-01 | Laboratorios Calier, S.A. | Procedimiento para combatir las infestaciones de las colmenas de abejas. |
| AU2003222990B2 (en) * | 2002-05-02 | 2009-11-12 | Cragmont Pharmaceuticals, Llc | Therapeutic 1,2,3,6-tetrahydropyrimidine-2-one compositions and methods therewith |
| EP3308772B8 (de) * | 2002-06-28 | 2021-03-17 | Civitas Therapeutics, Inc. | Epinephrin zur inhalation |
| US6669929B1 (en) | 2002-12-30 | 2003-12-30 | Colgate Palmolive Company | Dentifrice containing functional film flakes |
| US20050058672A1 (en) * | 2003-09-14 | 2005-03-17 | Bioderm Research | Baby Care Skin Protectant Compositions for Diaper Rash |
| DE10332486A1 (de) * | 2003-07-16 | 2005-02-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol für die Behandlung akuter Schmerzen |
| US7482378B2 (en) * | 2004-05-28 | 2009-01-27 | Millenium Specialty Chemicals, Inc. | Physiological cooling compositions |
| WO2006009825A1 (en) | 2004-06-17 | 2006-01-26 | Virun, Inc. | Compositions comprising a mucoadhesive protein and an active principle for mucosal delivery of said agents |
| ES2704482T3 (es) | 2004-11-24 | 2019-03-18 | Meda Pharmaceuticals Inc | Composiciones que comprenden azelastina y sus métodos de uso |
| US20060216359A1 (en) * | 2005-03-25 | 2006-09-28 | Lowell Riegel | Topical preparation for treating ulcerations on the inside of the month |
| TR200803299T1 (tr) * | 2005-11-10 | 2008-11-21 | Century Biologicals Private Limited | Solunum yolu rahatsızlıklarını tedavi etmek için kullanılan dengeli bir formülasyon. |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8679545B2 (en) | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| FR2900824A1 (fr) * | 2006-05-10 | 2007-11-16 | Prod Dentaires Pierre Rolland | Pate destinee a arreter les saignements, ses utilisations, et seringue la contenant |
| JP5230613B2 (ja) | 2006-05-23 | 2013-07-10 | テラコス・インコーポレイテッド | グルコース輸送体阻害剤およびその使用方法 |
| US7893053B2 (en) | 2006-06-16 | 2011-02-22 | Theracos, Inc. | Treating psychological conditions using muscarinic receptor M1 antagonists |
| US8748419B2 (en) | 2006-06-16 | 2014-06-10 | Theracos, Inc. | Treating obesity with muscarinic receptor M1 antagonists |
| US20080003280A1 (en) * | 2006-06-26 | 2008-01-03 | Levine Brian M | Combination cough treatment compounds and method of treating common coughs |
| CN101138541B (zh) * | 2006-09-06 | 2010-10-06 | 上海医药工业研究院 | 氨来占诺局部成膜凝胶组合物及其应用 |
| DK2064222T3 (da) | 2007-04-02 | 2014-07-21 | Theracos Inc | Benzyliske glycosid-derivater og fremgangsmåder til anvendelse deraf |
| RU2497526C2 (ru) | 2007-08-23 | 2013-11-10 | Теракос, Инк. | Производные бензилбензола и способы их применения |
| US20090123570A1 (en) * | 2007-11-09 | 2009-05-14 | Warner W Randolph | Composition and method for treating sore throat |
| MX349677B (es) | 2007-11-13 | 2017-08-08 | Meritage Pharma Inc | Composiciones corticosteroides. |
| US20090131386A1 (en) * | 2007-11-13 | 2009-05-21 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
| US20100216754A1 (en) * | 2007-11-13 | 2010-08-26 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
| US20090123551A1 (en) * | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Gastrointestinal delivery systems |
| US20090148530A1 (en) * | 2007-12-08 | 2009-06-11 | Jamie Koufman | Method for prevention and treatment of reflux injury in the aerodigestive tract and laryngopharynx caused by pepsin |
| US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
| US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
| KR20210107137A (ko) | 2008-04-21 | 2021-08-31 | 오토노미, 인코포레이티드 | 귀 질환 및 병태를 치료하기 위한 귀 조제물 |
| MX2011000637A (es) | 2008-07-15 | 2011-05-02 | Theracos Inc | Derivados deuretados de bencilbenceno y metodos de uso. |
| CA2731769C (en) | 2008-07-21 | 2013-09-10 | Otonomy, Inc. | Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders |
| US8784870B2 (en) | 2008-07-21 | 2014-07-22 | Otonomy, Inc. | Controlled release compositions for modulating free-radical induced damage and methods of use thereof |
| HUE051538T2 (hu) | 2008-08-20 | 2021-03-01 | Univ California | Kortikoszteroidok a gyomor-bél traktus gyulladásos betegségeinek kezelésére |
| SG193168A1 (en) | 2008-08-22 | 2013-09-30 | Theracos Inc | Processes for the preparation of sglt2 inhibitors |
| US7914828B2 (en) * | 2008-10-17 | 2011-03-29 | Levine Brian M | Combination herbal product to benefit respiratory tract |
| AU2009324894B2 (en) | 2008-11-25 | 2015-04-09 | University Of Rochester | MLK inhibitors and methods of use |
| GB201111485D0 (en) * | 2011-07-05 | 2011-08-17 | Biocopea Ltd | Drug composition and its use in therapy |
| EP2576549A4 (de) | 2010-05-24 | 2013-12-18 | Univ Rochester | Bizyklische heteroarylkinase-hemmer und verfahren zu ihrer verwendung |
| WO2011153712A1 (en) | 2010-06-12 | 2011-12-15 | Theracos, Inc. | Crystalline form of benzylbenzene sglt2 inhibitor |
| US8361519B2 (en) | 2010-11-18 | 2013-01-29 | Aadvantics Pharmaceuticals, Inc. | Combination herbal product to benefit respiratory tract in people exposed to smoke |
| WO2012112933A1 (en) | 2011-02-18 | 2012-08-23 | The Scripps Research Institute | Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate |
| US8524664B2 (en) | 2011-06-02 | 2013-09-03 | Colorado Seminary, Which owns and Operates The Univeristy of Denver | Methods of treating overproduction of cortisol using ACTH antagonist peptides |
| PL2819699T3 (pl) | 2012-02-27 | 2019-11-29 | Bayer New Zealand Ltd | Kompozycje o kontrolowanym uwalnianiu i sposoby ich zastosowania |
| WO2013188212A1 (en) * | 2012-06-15 | 2013-12-19 | University Of New Hampshire | Sustained release hydrogle-based stimulant |
| US9636360B2 (en) | 2012-09-18 | 2017-05-02 | pH Science Holdings, Inc | Method and composition for treating gastro-esophageal disorders |
| EP2925319B1 (de) | 2012-11-30 | 2019-01-09 | University Of Rochester | Mixed-lineage-kinaseinhibitoren für hiv/aids-therapien |
| US11135158B2 (en) | 2014-05-26 | 2021-10-05 | Michael Lee Martin | Medicated hard candy product for treating esophageal inflammation and a method using the same |
| ES2972665T3 (es) * | 2015-03-26 | 2024-06-13 | Patheon Softgels Inc | Cápsulas liquisoft |
| AU2016298307A1 (en) | 2015-07-28 | 2018-02-15 | Otonomy, Inc. | TrkB or TrkC agonist compositions and methods for the treatment of OTIC conditions |
| BR112018006199B1 (pt) | 2015-09-28 | 2023-10-24 | Evonik Operations Gmbh | Composições orais antimicrobianas à base de sílica |
| CA3029281A1 (en) | 2016-06-29 | 2018-01-04 | Otonomy, Inc. | Triglyceride otic formulations and uses thereof |
| WO2019154895A1 (en) | 2018-02-08 | 2019-08-15 | Strekin Ag | Gel formulation for preventing or treating hearing loss |
| JP2022524486A (ja) * | 2019-03-14 | 2022-05-06 | イントラモント テクノロジーズ，インコーポレイテッド | 口腔および咽頭を介して罹患する疾病の予防のための製剤 |
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|---|---|---|---|---|
| US3352752A (en) * | 1963-07-25 | 1967-11-14 | Tintex Corp | Intestinal adsorbent compositions |
| US4042679A (en) * | 1975-11-07 | 1977-08-16 | Colgate-Palmolive Company | Antibacterial oral composition |
| ZA831186B (en) * | 1982-03-22 | 1983-11-30 | Upjohn Ltd | Gelled pge2/triacetin solutions |
| US4427681A (en) * | 1982-09-16 | 1984-01-24 | Richardson-Vicks, Inc. | Thixotropic compositions easily convertible to pourable liquids |
| NL193682C (nl) * | 1987-05-14 | 2000-07-04 | Glaxo Group Ltd | Beklede cefuroximaxetilsamenstelling. |
| US5047244A (en) * | 1988-06-03 | 1991-09-10 | Watson Laboratories, Inc. | Mucoadhesive carrier for delivery of therapeutical agent |
| US4980175A (en) * | 1989-01-03 | 1990-12-25 | Leonard Chavkin | Liquid orally administrable compositions based on edible oils |
| US4988679A (en) * | 1989-01-03 | 1991-01-29 | Leonard Chavkin | Liquid sustained release composition |
| US5112604A (en) * | 1989-09-01 | 1992-05-12 | Riker Laboratories, Inc. | Oral suspension formulation |
| EP0452334A4 (en) * | 1989-10-31 | 1991-12-11 | Watson Laboratoires, Inc. | Mucoadhesive carrier for delivery of therapeutical agent |
| JPH0639368B2 (ja) * | 1990-02-28 | 1994-05-25 | 株式会社萩原技研 | シリカゲルを母体とした抗菌性組生物 |
| US5458879A (en) * | 1994-03-03 | 1995-10-17 | The Procter & Gamble Company | Oral vehicle compositions |
| US5585115A (en) * | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
| WO1996021432A1 (en) * | 1995-01-11 | 1996-07-18 | Cygnus, Inc. | Delivery of active substances by way of mucosal surfaces of pharyngeal and esophageal regions |
| IT1275955B1 (it) * | 1995-03-22 | 1997-10-24 | Dompe Spa | Formulazioni farmaceutiche in forma di gel tissotropico |
| US5589160A (en) * | 1995-05-02 | 1996-12-31 | The Procter & Gamble Company | Dentifrice compositions |
| US5658553A (en) * | 1995-05-02 | 1997-08-19 | The Procter & Gamble Company | Dentifrice compositions |
| US6184220B1 (en) * | 1998-03-27 | 2001-02-06 | Boehringer Ingelheim Pharma Kg | Oral suspension of pharmaceutical substance |
| US20020009478A1 (en) * | 1998-08-24 | 2002-01-24 | Douglas Joseph Dobrozsi | Oral liquid mucoadhesive compositions |
-
1999
- 1999-07-27 US US09/361,542 patent/US20020009478A1/en not_active Abandoned
- 1999-08-24 ES ES99942428T patent/ES2185395T3/es not_active Expired - Lifetime
- 1999-08-24 KR KR1020017001962A patent/KR20010074834A/ko not_active Application Discontinuation
- 1999-08-24 WO PCT/US1999/019201 patent/WO2000010528A1/en not_active Application Discontinuation
- 1999-08-24 DK DK99942428T patent/DK1107732T3/da active
- 1999-08-24 CA CA002338480A patent/CA2338480C/en not_active Expired - Fee Related
- 1999-08-24 TR TR2001/00569T patent/TR200100569T2/xx unknown
- 1999-08-24 EP EP99942428A patent/EP1107732B1/de not_active Expired - Lifetime
- 1999-08-24 DE DE69904057T patent/DE69904057T2/de not_active Expired - Lifetime
- 1999-08-24 AT AT99942428T patent/ATE227978T1/de not_active IP Right Cessation
- 1999-08-24 CO CO99053435A patent/CO5140074A1/es unknown
- 1999-08-24 JP JP2000565850A patent/JP2002523353A/ja not_active Withdrawn
- 1999-08-24 HU HU0103217A patent/HUP0103217A2/hu unknown
- 1999-08-24 CN CN99809845A patent/CN1313754A/zh active Pending
- 1999-08-24 BR BR9913148-0A patent/BR9913148A/pt not_active IP Right Cessation
- 1999-08-24 PE PE1999000850A patent/PE20000863A1/es not_active Application Discontinuation
- 1999-08-24 AU AU55808/99A patent/AU753251B2/en not_active Ceased
-
2001
- 2001-02-19 NO NO20010830A patent/NO20010830D0/no not_active Application Discontinuation
- 2001-12-07 US US10/021,327 patent/US6638521B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2338480A1 (en) | 2000-03-02 |
| US6638521B2 (en) | 2003-10-28 |
| CO5140074A1 (es) | 2002-03-22 |
| NO20010830L (no) | 2001-02-19 |
| US20020009478A1 (en) | 2002-01-24 |
| JP2002523353A (ja) | 2002-07-30 |
| DE69904057T2 (de) | 2003-08-21 |
| ATE227978T1 (de) | 2002-12-15 |
| PE20000863A1 (es) | 2000-09-12 |
| EP1107732A1 (de) | 2001-06-20 |
| CA2338480C (en) | 2004-10-05 |
| WO2000010528A1 (en) | 2000-03-02 |
| HUP0103217A2 (hu) | 2001-12-28 |
| ES2185395T3 (es) | 2003-04-16 |
| CN1313754A (zh) | 2001-09-19 |
| AU753251B2 (en) | 2002-10-10 |
| DE69904057D1 (de) | 2003-01-02 |
| AU5580899A (en) | 2000-03-14 |
| NO20010830D0 (no) | 2001-02-19 |
| BR9913148A (pt) | 2001-09-25 |
| TR200100569T2 (tr) | 2001-07-23 |
| US20020076421A1 (en) | 2002-06-20 |
| KR20010074834A (ko) | 2001-08-09 |
| EP1107732B1 (de) | 2002-11-20 |
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