DK1092715T3 - Cyanoindolderivater som inhibitorer for serotoningenoptagelse, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse - Google Patents
Cyanoindolderivater som inhibitorer for serotoningenoptagelse, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disseInfo
- Publication number
- DK1092715T3 DK1092715T3 DK00402799T DK00402799T DK1092715T3 DK 1092715 T3 DK1092715 T3 DK 1092715T3 DK 00402799 T DK00402799 T DK 00402799T DK 00402799 T DK00402799 T DK 00402799T DK 1092715 T3 DK1092715 T3 DK 1092715T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- cyanoindole
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9912668A FR2799463B1 (fr) | 1999-10-12 | 1999-10-12 | Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent |
EP00402799A EP1092715B1 (fr) | 1999-10-12 | 2000-10-11 | Composés cyano-indoles inhibiteurs de recapture de sérotonine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1092715T3 true DK1092715T3 (da) | 2005-07-25 |
Family
ID=9550799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00402799T DK1092715T3 (da) | 1999-10-12 | 2000-10-11 | Cyanoindolderivater som inhibitorer for serotoningenoptagelse, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse |
Country Status (23)
Country | Link |
---|---|
US (1) | US6492366B1 (pt) |
EP (1) | EP1092715B1 (pt) |
JP (1) | JP3274454B2 (pt) |
KR (1) | KR100470692B1 (pt) |
CN (1) | CN1146568C (pt) |
AT (1) | ATE291577T1 (pt) |
AU (1) | AU774741B2 (pt) |
BR (1) | BR0004764A (pt) |
CA (1) | CA2323703C (pt) |
DE (1) | DE60018869T2 (pt) |
DK (1) | DK1092715T3 (pt) |
EA (1) | EA003831B1 (pt) |
ES (1) | ES2238260T3 (pt) |
FR (1) | FR2799463B1 (pt) |
HK (1) | HK1036062A1 (pt) |
HU (1) | HUP0003991A2 (pt) |
MX (1) | MXPA00009642A (pt) |
NO (1) | NO321242B1 (pt) |
NZ (1) | NZ507458A (pt) |
PL (1) | PL343148A1 (pt) |
PT (1) | PT1092715E (pt) |
SI (1) | SI1092715T1 (pt) |
ZA (1) | ZA200005625B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6693202B1 (en) | 1999-02-16 | 2004-02-17 | Theravance, Inc. | Muscarinic receptor antagonists |
US6559169B2 (en) | 2001-04-24 | 2003-05-06 | Wyeth | Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-benzodioxan |
US7041683B2 (en) | 2001-04-24 | 2006-05-09 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan |
US7276603B2 (en) * | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
WO2005113833A2 (en) * | 2004-05-21 | 2005-12-01 | Duke University | Polymorphism in tryptophan hydroxylase-2 controls brain serotonin synthesis |
WO2012054815A1 (en) | 2010-10-22 | 2012-04-26 | Duke University | Slow-release formulations of 5-hydroxytryptophan as an adjunct to pro-serotonergic therapies |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2043709C (en) * | 1990-06-29 | 2002-01-22 | David W. Smith | Antimigraine alkoxypyrimidine derivatives |
HUT64326A (en) * | 1990-10-15 | 1993-12-28 | Pfizer | Process for production indole derivatives and pharmaceutical preparations containing these compounds |
GB9208161D0 (en) * | 1992-04-14 | 1992-05-27 | Pfizer Ltd | Indoles |
FR2701026B1 (fr) * | 1993-02-02 | 1995-03-31 | Adir | Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
IT1271352B (it) * | 1993-04-08 | 1997-05-27 | Boehringer Ingelheim Italia | Derivati dell'indolo utili nel trattamento dei disturbi del sistema nervoso centrale |
ES2079323B1 (es) * | 1994-06-21 | 1996-10-16 | Vita Invest Sa | Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes. |
AU2809295A (en) * | 1994-07-11 | 1996-02-09 | Dsm N.V. | Multihydroxy-functional oligophenylene oxide |
AR004229A1 (es) * | 1995-11-06 | 1998-11-04 | Wyeth Corp | Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos |
US5912256A (en) * | 1996-06-20 | 1999-06-15 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
US5998462A (en) * | 1996-12-16 | 1999-12-07 | Allelix Biopharmaceuticals Inc. | 5-alkyl indole compounds |
-
1999
- 1999-10-12 FR FR9912668A patent/FR2799463B1/fr not_active Expired - Fee Related
-
2000
- 2000-10-02 MX MXPA00009642A patent/MXPA00009642A/es active IP Right Grant
- 2000-10-10 NO NO20005103A patent/NO321242B1/no unknown
- 2000-10-10 BR BR0004764-3A patent/BR0004764A/pt not_active IP Right Cessation
- 2000-10-11 NZ NZ507458A patent/NZ507458A/xx unknown
- 2000-10-11 EA EA200000929A patent/EA003831B1/ru not_active IP Right Cessation
- 2000-10-11 US US09/686,056 patent/US6492366B1/en not_active Expired - Fee Related
- 2000-10-11 SI SI200030652T patent/SI1092715T1/xx unknown
- 2000-10-11 DK DK00402799T patent/DK1092715T3/da active
- 2000-10-11 AT AT00402799T patent/ATE291577T1/de not_active IP Right Cessation
- 2000-10-11 DE DE60018869T patent/DE60018869T2/de not_active Expired - Fee Related
- 2000-10-11 ES ES00402799T patent/ES2238260T3/es not_active Expired - Lifetime
- 2000-10-11 EP EP00402799A patent/EP1092715B1/fr not_active Expired - Lifetime
- 2000-10-11 PT PT00402799T patent/PT1092715E/pt unknown
- 2000-10-12 HU HU0003991A patent/HUP0003991A2/hu unknown
- 2000-10-12 CN CNB001314068A patent/CN1146568C/zh not_active Expired - Fee Related
- 2000-10-12 CA CA002323703A patent/CA2323703C/fr not_active Expired - Fee Related
- 2000-10-12 KR KR10-2000-0060013A patent/KR100470692B1/ko not_active IP Right Cessation
- 2000-10-12 AU AU65479/00A patent/AU774741B2/en not_active Ceased
- 2000-10-12 PL PL00343148A patent/PL343148A1/xx not_active Application Discontinuation
- 2000-10-12 JP JP2000311550A patent/JP3274454B2/ja not_active Expired - Fee Related
- 2000-10-12 ZA ZA200005625A patent/ZA200005625B/xx unknown
-
2001
- 2001-09-25 HK HK01106737A patent/HK1036062A1/xx not_active IP Right Cessation
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