DK1083881T3 - Liposomsammensætninger indeholdende et quinolonderivat og deres anvendelse som antibakterielle midler - Google Patents

Liposomsammensætninger indeholdende et quinolonderivat og deres anvendelse som antibakterielle midler

Info

Publication number
DK1083881T3
DK1083881T3 DK99916160T DK99916160T DK1083881T3 DK 1083881 T3 DK1083881 T3 DK 1083881T3 DK 99916160 T DK99916160 T DK 99916160T DK 99916160 T DK99916160 T DK 99916160T DK 1083881 T3 DK1083881 T3 DK 1083881T3
Authority
DK
Denmark
Prior art keywords
compositions containing
antibacterial agents
liposome compositions
quinolone derivative
liposome
Prior art date
Application number
DK99916160T
Other languages
English (en)
Inventor
Samuel Zalipsky
Francis J Martin
Luke S S Guo
Josh Gittelman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DK1083881T3 publication Critical patent/DK1083881T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK99916160T 1998-04-02 1999-03-24 Liposomsammensætninger indeholdende et quinolonderivat og deres anvendelse som antibakterielle midler DK1083881T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/054,857 US5972379A (en) 1995-02-14 1998-04-02 Liposome composition and method for administering a quinolone
EP99916160A EP1083881B1 (en) 1998-04-02 1999-03-24 LIPOSOME COMPOSITIONs containing a quinolone derivative AND their use as antibacterial agents

Publications (1)

Publication Number Publication Date
DK1083881T3 true DK1083881T3 (da) 2005-01-03

Family

ID=21993954

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99916160T DK1083881T3 (da) 1998-04-02 1999-03-24 Liposomsammensætninger indeholdende et quinolonderivat og deres anvendelse som antibakterielle midler

Country Status (17)

Country Link
US (1) US5972379A (da)
EP (1) EP1083881B1 (da)
JP (1) JP2002510611A (da)
KR (1) KR100617921B1 (da)
CN (1) CN1149978C (da)
AT (1) ATE274342T1 (da)
AU (1) AU763989B2 (da)
CA (1) CA2326497A1 (da)
DE (1) DE69919698T2 (da)
DK (1) DK1083881T3 (da)
ES (1) ES2226371T3 (da)
HK (1) HK1035331A1 (da)
IL (1) IL138685A0 (da)
NZ (1) NZ506970A (da)
PT (1) PT1083881E (da)
WO (1) WO1999051202A2 (da)
ZA (1) ZA200005333B (da)

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ES2253398T3 (es) * 2000-06-30 2006-06-01 Inex Pharmaceuticals Corp. Camptotecinas liposomales mejoradas y sus usos.
US7452550B2 (en) 2000-06-30 2008-11-18 Hana Biosciences, Inc. Liposomal antineoplastic drugs and uses thereof
KR100874847B1 (ko) * 2001-06-01 2008-12-19 아스텔라스 파마 유럽 비.브이. 지질-폴리머-접합체
EP1429726A2 (en) * 2001-09-06 2004-06-23 Yissum Research Development Company Of The Hebrew University Of Jerusalem A method for preparing liposome formulations with a predefined release profile
US20040219201A1 (en) * 2001-12-06 2004-11-04 Yechezkel Barenholz Tempamine compositions and methods of use
JP4619658B2 (ja) * 2002-03-12 2011-01-26 富山化学工業株式会社 快い味の経口懸濁液および方法
MXPA05004580A (es) * 2002-10-29 2005-07-26 Transave Inc Liberacion sostenida de anti - infecciosos.
US7718189B2 (en) 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
EP1628637A2 (en) * 2003-05-30 2006-03-01 Alza Corporation Method of pulmonary administration of an agent
CN100431525C (zh) * 2003-07-17 2008-11-12 台湾东洋药品工业股份有限公司 脂质体悬浮液制造方法及含该法所制脂质体悬浮液的产物
US8173840B2 (en) * 2003-07-29 2012-05-08 Signature R&D Holdings, Llc Compounds with high therapeutic index
NZ601780A (en) * 2003-07-29 2012-10-26 Signature R & D Holdings Llc Amino Acid Prodrugs
US7589233B2 (en) * 2003-07-29 2009-09-15 Signature R&D Holdings, Llc L-Threonine derivatives of high therapeutic index
US7915223B2 (en) * 2004-09-27 2011-03-29 Technion Research & Development Foundation Ltd. Antimicrobial agents
US20060078624A1 (en) * 2004-09-29 2006-04-13 Samuel Zalipsky Microparticles and nanoparticles containing a lipopolymer
TW200618820A (en) * 2004-11-05 2006-06-16 Alza Corp Liposome formulations of boronic acid compounds
CN100403535C (zh) * 2005-05-18 2008-07-16 崇贸科技股份有限公司 可控制触发电压的静电放电装置
PL1962805T3 (pl) 2005-12-08 2017-01-31 Insmed Incorporated Kompozycje środków przeciwzapalnych oparte na lipidach do leczenia infekcji płucnych
US8268347B1 (en) 2006-10-24 2012-09-18 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
US8071127B2 (en) 2006-10-24 2011-12-06 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
US8119156B2 (en) 2006-10-24 2012-02-21 Aradigm Corporation Dual action, inhaled formulations providing both an immediate and sustained release profile
KR100916160B1 (ko) * 2007-02-21 2009-09-08 (주)바이오버드 약제학적 항암 조성물
WO2008132737A1 (en) * 2007-04-30 2008-11-06 Technion Research & Development Foundation Ltd. Novel antimicrobial agents
US20100173832A1 (en) * 2007-04-30 2010-07-08 Technion Research & Development Foundation Ltd. Anticancerous polymeric agents
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
EP2480208A1 (en) 2009-09-23 2012-08-01 Indu Javeri Methods for the preparation of liposomes
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
CN102309448B (zh) * 2010-06-29 2014-07-09 中国人民解放军军事医学科学院毒物药物研究所 一种肺部给药的环丙沙星药用组合物及其制备方法
CN102188430B (zh) * 2011-04-06 2012-08-15 广东如来医药进出口有限公司 司帕沙星化合物的组合物制剂及其制备方法
KR102277921B1 (ko) 2012-05-21 2021-07-14 인스메드 인코포레이티드 폐 감염을 치료하기 위한 시스템
MX2015005992A (es) 2012-11-20 2016-03-07 Spectrum Pharmaceuticals Inc Metodo mejorado para la preparacion de la vincristina liposomal encapsulada para el uso terapeutico.
CA2891487A1 (en) 2012-11-29 2014-06-05 Insmed Incorporated Stabilized vancomycin formulations
US9987227B2 (en) 2013-10-22 2018-06-05 Aradigm Corporation Inhaled surfactant-modified liposomal formulations providing both an immediate and sustained release profile
PL3142643T3 (pl) 2014-05-15 2019-12-31 Insmed Incorporated Sposoby leczenia zakażeń płuc prątkami niegruźliczymi
EP2957561A1 (en) * 2014-06-18 2015-12-23 Université Paris 6 Pierre et Marie Curie UPMC Novel fluoroquinolones and use thereof to treat bacterial infections
TWI678213B (zh) 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
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US20170172921A1 (en) * 2016-12-14 2017-06-22 Mahmoud Reza Jaafari Polyphenolic compounds encapsualated in long circulating liposomes and use thereof
US11964050B2 (en) 2017-07-24 2024-04-23 Pharmosa Biopharm Inc. Liposome compositions comprising weak acid drugs and uses thereof
CN109305987B (zh) * 2017-07-27 2021-04-20 济南大学 环丙沙星金属配合物及其制备方法和应用
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Also Published As

Publication number Publication date
ZA200005333B (en) 2001-10-31
WO1999051202A2 (en) 1999-10-14
PT1083881E (pt) 2004-11-30
EP1083881A2 (en) 2001-03-21
DE69919698D1 (de) 2004-09-30
DE69919698T2 (de) 2005-05-25
CN1295465A (zh) 2001-05-16
US5972379A (en) 1999-10-26
KR20010034727A (ko) 2001-04-25
KR100617921B1 (ko) 2006-08-30
EP1083881B1 (en) 2004-08-25
ATE274342T1 (de) 2004-09-15
HK1035331A1 (en) 2001-11-23
AU763989B2 (en) 2003-08-07
CN1149978C (zh) 2004-05-19
AU3453399A (en) 1999-10-25
JP2002510611A (ja) 2002-04-09
ES2226371T3 (es) 2005-03-16
IL138685A0 (en) 2001-10-31
WO1999051202A3 (en) 1999-11-18
CA2326497A1 (en) 1999-10-14
NZ506970A (en) 2003-07-25

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