ZA200005333B - Quinolone containing liposomes and their use as anti-bacterial agents. - Google Patents
Quinolone containing liposomes and their use as anti-bacterial agents.Info
- Publication number
- ZA200005333B ZA200005333B ZA200005333A ZA200005333A ZA200005333B ZA 200005333 B ZA200005333 B ZA 200005333B ZA 200005333 A ZA200005333 A ZA 200005333A ZA 200005333 A ZA200005333 A ZA 200005333A ZA 200005333 B ZA200005333 B ZA 200005333B
- Authority
- ZA
- South Africa
- Prior art keywords
- bacterial agents
- containing liposomes
- quinolone containing
- quinolone
- liposomes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/054,857 US5972379A (en) | 1995-02-14 | 1998-04-02 | Liposome composition and method for administering a quinolone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200005333B true ZA200005333B (en) | 2001-10-31 |
Family
ID=21993954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200005333A ZA200005333B (en) | 1998-04-02 | 2000-10-02 | Quinolone containing liposomes and their use as anti-bacterial agents. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5972379A (xx) |
| EP (1) | EP1083881B1 (xx) |
| JP (1) | JP2002510611A (xx) |
| KR (1) | KR100617921B1 (xx) |
| CN (1) | CN1149978C (xx) |
| AT (1) | ATE274342T1 (xx) |
| AU (1) | AU763989B2 (xx) |
| CA (1) | CA2326497A1 (xx) |
| DE (1) | DE69919698T2 (xx) |
| DK (1) | DK1083881T3 (xx) |
| ES (1) | ES2226371T3 (xx) |
| HK (1) | HK1035331A1 (xx) |
| IL (1) | IL138685A0 (xx) |
| NZ (1) | NZ506970A (xx) |
| PT (1) | PT1083881E (xx) |
| WO (1) | WO1999051202A2 (xx) |
| ZA (1) | ZA200005333B (xx) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7311924B2 (en) | 1999-04-01 | 2007-12-25 | Hana Biosciences, Inc. | Compositions and methods for treating cancer |
| US20030147944A1 (en) * | 1999-12-10 | 2003-08-07 | Mayer Lawrence D | Lipid carrier compositions with protected surface reactive functions |
| ATE309786T1 (de) | 2000-06-30 | 2005-12-15 | Inex Pharmaceuticals Corp | Liposomale antineoplastische arzneimittel und deren verwendungen |
| US7452550B2 (en) | 2000-06-30 | 2008-11-18 | Hana Biosciences, Inc. | Liposomal antineoplastic drugs and uses thereof |
| HUP0400171A2 (en) * | 2001-06-01 | 2007-02-28 | Astellas Pharma Europ B V | Lipid-polymer-conjugates |
| AU2002334358B2 (en) * | 2001-09-06 | 2008-02-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A method for preparing liposome formulations with a predefined release profile |
| US20040219201A1 (en) * | 2001-12-06 | 2004-11-04 | Yechezkel Barenholz | Tempamine compositions and methods of use |
| EP1482789A4 (en) * | 2002-03-12 | 2010-12-29 | Toyama Chemical Company Ltd | TASTY ORAL SUSPENSION AND METHOD |
| CA2504317C (en) * | 2002-10-29 | 2012-05-22 | Transave, Inc. | Sustained release of antiinfectives |
| US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
| WO2004110493A2 (en) * | 2003-05-30 | 2004-12-23 | Alza Corporation | Method of pulmonary administration of an agent |
| CN100431525C (zh) * | 2003-07-17 | 2008-11-12 | 台湾东洋药品工业股份有限公司 | 脂质体悬浮液制造方法及含该法所制脂质体悬浮液的产物 |
| US7589233B2 (en) * | 2003-07-29 | 2009-09-15 | Signature R&D Holdings, Llc | L-Threonine derivatives of high therapeutic index |
| US8173840B2 (en) * | 2003-07-29 | 2012-05-08 | Signature R&D Holdings, Llc | Compounds with high therapeutic index |
| WO2005046575A2 (en) * | 2003-07-29 | 2005-05-26 | Signature R & D Holdings, Lcc | Amino acid prodrugs |
| US7915223B2 (en) * | 2004-09-27 | 2011-03-29 | Technion Research & Development Foundation Ltd. | Antimicrobial agents |
| AU2005292083A1 (en) * | 2004-09-29 | 2006-04-13 | Alza Corporation | Microparticles and nanoparticles containing a lipopolymer |
| TW200618820A (en) * | 2004-11-05 | 2006-06-16 | Alza Corp | Liposome formulations of boronic acid compounds |
| CN100403535C (zh) * | 2005-05-18 | 2008-07-16 | 崇贸科技股份有限公司 | 可控制触发电压的静电放电装置 |
| EP3067047B1 (en) | 2005-12-08 | 2022-04-20 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections |
| US8268347B1 (en) | 2006-10-24 | 2012-09-18 | Aradigm Corporation | Dual action, inhaled formulations providing both an immediate and sustained release profile |
| US8071127B2 (en) | 2006-10-24 | 2011-12-06 | Aradigm Corporation | Dual action, inhaled formulations providing both an immediate and sustained release profile |
| US8119156B2 (en) | 2006-10-24 | 2012-02-21 | Aradigm Corporation | Dual action, inhaled formulations providing both an immediate and sustained release profile |
| KR100916160B1 (ko) * | 2007-02-21 | 2009-09-08 | (주)바이오버드 | 약제학적 항암 조성물 |
| US20100173832A1 (en) * | 2007-04-30 | 2010-07-08 | Technion Research & Development Foundation Ltd. | Anticancerous polymeric agents |
| EP2152289A1 (en) * | 2007-04-30 | 2010-02-17 | Technion Research & Development Foundation Ltd. | Novel antimicrobial agents |
| US20100196455A1 (en) | 2007-05-04 | 2010-08-05 | Transave, Inc. | Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof |
| US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
| WO2011038073A1 (en) * | 2009-09-23 | 2011-03-31 | Formatech, Inc. | Methods for the preparation of liposomes comprising docetaxel |
| CN102309448B (zh) * | 2010-06-29 | 2014-07-09 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种肺部给药的环丙沙星药用组合物及其制备方法 |
| CN102188430B (zh) * | 2011-04-06 | 2012-08-15 | 广东如来医药进出口有限公司 | 司帕沙星化合物的组合物制剂及其制备方法 |
| NZ719739A (en) | 2012-05-21 | 2017-07-28 | Insmed Inc | Systems for treating pulmonary infections |
| KR102186116B1 (ko) | 2012-11-20 | 2020-12-03 | 스펙트럼 파마슈티컬즈 인크 | 치료적 사용을 위한 리포솜 캡슐화 빈크리스틴을 제조하기 위한 개선된 방법 |
| EP3581186A1 (en) | 2012-11-29 | 2019-12-18 | Insmed Incorporated | Stabilized vancomycin formulations |
| US9987227B2 (en) | 2013-10-22 | 2018-06-05 | Aradigm Corporation | Inhaled surfactant-modified liposomal formulations providing both an immediate and sustained release profile |
| PT3142643T (pt) | 2014-05-15 | 2019-10-28 | Insmed Inc | Métodos para o tratamento de infeções mico bacterianas pulmonares não tuberculares |
| EP2957561A1 (en) * | 2014-06-18 | 2015-12-23 | Université Paris 6 Pierre et Marie Curie UPMC | Novel fluoroquinolones and use thereof to treat bacterial infections |
| TWI678213B (zh) | 2015-07-22 | 2019-12-01 | 美商史倍壯製藥公司 | 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物 |
| GB2552301A (en) * | 2016-07-11 | 2018-01-24 | Evox Therapeutics Ltd | Metabolic drug loading of EVs |
| US20170172921A1 (en) * | 2016-12-14 | 2017-06-22 | Mahmoud Reza Jaafari | Polyphenolic compounds encapsualated in long circulating liposomes and use thereof |
| KR102337566B1 (ko) * | 2017-07-24 | 2021-12-14 | 파모사 바이오팜 인코포레이티드 | 약산성 약물을 포함하는 리포솜 조성물 및 이의 용도 |
| CN109305987B (zh) * | 2017-07-27 | 2021-04-20 | 济南大学 | 环丙沙星金属配合物及其制备方法和应用 |
| US11571386B2 (en) | 2018-03-30 | 2023-02-07 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5077056A (en) * | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
| ATE63124T1 (de) * | 1986-03-14 | 1991-05-15 | Fujisawa Pharmaceutical Co | Prodrugverbindungen, verfahren zu deren herstellung und diese enthaltende zubereitungen mit verzoegerter freisetzung. |
| US5057523A (en) * | 1988-09-22 | 1991-10-15 | Abbott Laboratories | Dipeptide quinolone derivatives |
| IL91664A (en) * | 1988-09-28 | 1993-05-13 | Yissum Res Dev Co | Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release |
| WO1991009616A1 (en) * | 1989-12-22 | 1991-07-11 | Yale University | Quinolone antibiotics encapsulated in lipid vesicles |
| CA2087965A1 (en) * | 1990-07-30 | 1992-02-01 | Ajoy Chakrabarti | Accumulation of amino acids and peptides into liposomes |
| CA2101241C (en) * | 1993-07-23 | 1998-12-22 | Jonathan P. Wong | Liposome-encapsulated ciprofloxacin |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| US5741516A (en) * | 1994-06-20 | 1998-04-21 | Inex Pharmaceuticals Corporation | Sphingosomes for enhanced drug delivery |
| AU4981896A (en) * | 1995-02-14 | 1996-09-04 | Sequus Pharmaceuticals, Inc. | Liposome composition and method for administering liposome-loadable drugs |
| US5800833A (en) * | 1995-02-27 | 1998-09-01 | University Of British Columbia | Method for loading lipid vesicles |
| CA2263455C (en) * | 1996-08-23 | 2002-10-29 | Sequus Pharmaceuticals, Inc. | Liposomes containing a cisplatin compound |
| US5837282A (en) * | 1996-10-30 | 1998-11-17 | University Of British Columbia | Ionophore-mediated liposome loading |
-
1998
- 1998-04-02 US US09/054,857 patent/US5972379A/en not_active Expired - Lifetime
-
1999
- 1999-03-24 DE DE69919698T patent/DE69919698T2/de not_active Expired - Fee Related
- 1999-03-24 AT AT99916160T patent/ATE274342T1/de not_active IP Right Cessation
- 1999-03-24 AU AU34533/99A patent/AU763989B2/en not_active Ceased
- 1999-03-24 KR KR1020007010987A patent/KR100617921B1/ko not_active IP Right Cessation
- 1999-03-24 EP EP99916160A patent/EP1083881B1/en not_active Expired - Lifetime
- 1999-03-24 NZ NZ506970A patent/NZ506970A/en unknown
- 1999-03-24 ES ES99916160T patent/ES2226371T3/es not_active Expired - Lifetime
- 1999-03-24 WO PCT/US1999/006500 patent/WO1999051202A2/en not_active Application Discontinuation
- 1999-03-24 DK DK99916160T patent/DK1083881T3/da active
- 1999-03-24 PT PT99916160T patent/PT1083881E/pt unknown
- 1999-03-24 CN CNB998046558A patent/CN1149978C/zh not_active Expired - Fee Related
- 1999-03-24 JP JP2000541974A patent/JP2002510611A/ja active Pending
- 1999-03-24 IL IL13868599A patent/IL138685A0/xx unknown
- 1999-03-24 CA CA002326497A patent/CA2326497A1/en not_active Abandoned
-
2000
- 2000-10-02 ZA ZA200005333A patent/ZA200005333B/xx unknown
-
2001
- 2001-08-31 HK HK01106151A patent/HK1035331A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE274342T1 (de) | 2004-09-15 |
| EP1083881A2 (en) | 2001-03-21 |
| US5972379A (en) | 1999-10-26 |
| IL138685A0 (en) | 2001-10-31 |
| CN1295465A (zh) | 2001-05-16 |
| AU763989B2 (en) | 2003-08-07 |
| AU3453399A (en) | 1999-10-25 |
| CN1149978C (zh) | 2004-05-19 |
| KR100617921B1 (ko) | 2006-08-30 |
| JP2002510611A (ja) | 2002-04-09 |
| PT1083881E (pt) | 2004-11-30 |
| CA2326497A1 (en) | 1999-10-14 |
| WO1999051202A3 (en) | 1999-11-18 |
| EP1083881B1 (en) | 2004-08-25 |
| KR20010034727A (ko) | 2001-04-25 |
| HK1035331A1 (en) | 2001-11-23 |
| DK1083881T3 (da) | 2005-01-03 |
| WO1999051202A2 (en) | 1999-10-14 |
| DE69919698D1 (de) | 2004-09-30 |
| ES2226371T3 (es) | 2005-03-16 |
| DE69919698T2 (de) | 2005-05-25 |
| NZ506970A (en) | 2003-07-25 |
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