DK1068210T3 - Fremgangsmåde til fremstilling af purinderivater - Google Patents

Fremgangsmåde til fremstilling af purinderivater

Info

Publication number
DK1068210T3
DK1068210T3 DK99917959T DK99917959T DK1068210T3 DK 1068210 T3 DK1068210 T3 DK 1068210T3 DK 99917959 T DK99917959 T DK 99917959T DK 99917959 T DK99917959 T DK 99917959T DK 1068210 T3 DK1068210 T3 DK 1068210T3
Authority
DK
Denmark
Prior art keywords
12alkyl
formula
compound
preparation
hydrogen
Prior art date
Application number
DK99917959T
Other languages
English (en)
Inventor
Graham Richard Geen
Andrew Colin Share
Original Assignee
Novartis Int Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Int Pharm Ltd filed Critical Novartis Int Pharm Ltd
Application granted granted Critical
Publication of DK1068210T3 publication Critical patent/DK1068210T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/40Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32Nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK99917959T 1998-04-02 1999-03-30 Fremgangsmåde til fremstilling af purinderivater DK1068210T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9807116.0A GB9807116D0 (en) 1998-04-02 1998-04-02 Novel process

Publications (1)

Publication Number Publication Date
DK1068210T3 true DK1068210T3 (da) 2004-09-20

Family

ID=10829765

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99917959T DK1068210T3 (da) 1998-04-02 1999-03-30 Fremgangsmåde til fremstilling af purinderivater

Country Status (17)

Country Link
US (1) US6437125B1 (da)
EP (1) EP1068210B1 (da)
JP (1) JP4459439B2 (da)
KR (1) KR100613812B1 (da)
CN (1) CN1125068C (da)
AT (1) ATE268332T1 (da)
AU (1) AU3605199A (da)
BR (1) BR9908959A (da)
CA (1) CA2323965A1 (da)
DE (1) DE69917765T2 (da)
DK (1) DK1068210T3 (da)
ES (1) ES2222702T3 (da)
GB (1) GB9807116D0 (da)
HK (1) HK1035896A1 (da)
IL (1) IL138289A0 (da)
PT (1) PT1068210E (da)
WO (1) WO1999051604A2 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1288215B8 (en) 2001-08-30 2005-04-06 Ajinomoto Co., Inc. Production method of famciclovir and production and crystallization method of intermediate therefor
WO2004018470A2 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
WO2005116031A1 (en) * 2004-05-18 2005-12-08 Teva Pharmaceutical Industries Ltd. Drying process for preparing crystalline solid famciclovir
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
CN110386935A (zh) * 2018-04-20 2019-10-29 重庆常捷医药有限公司 一种泛昔洛韦中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485225D1 (de) 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
US5684153A (en) * 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
DE3582399D1 (de) 1984-09-20 1991-05-08 Beecham Group Plc Purin-derivate und ihre pharmazeutische verwendung.
GB8817607D0 (en) 1988-07-23 1988-09-01 Beecham Group Plc Novel process
US5688948A (en) * 1991-09-18 1997-11-18 Ajinomoto Co., Inc. Process for isomerizing acyclic nucleosides and process for separating purine nucleosides
GB9407698D0 (en) 1994-04-19 1994-06-15 Smithkline Beecham Plc Pharmaceuticals
EP0827960A1 (en) * 1996-09-10 1998-03-11 Ajinomoto Co., Inc. Process for producing purine derivatives

Also Published As

Publication number Publication date
CN1294591A (zh) 2001-05-09
IL138289A0 (en) 2001-10-31
AU3605199A (en) 1999-10-25
JP4459439B2 (ja) 2010-04-28
WO1999051604A3 (en) 2000-02-17
KR100613812B1 (ko) 2006-08-18
GB9807116D0 (en) 1998-06-03
DE69917765D1 (de) 2004-07-08
ATE268332T1 (de) 2004-06-15
PT1068210E (pt) 2004-10-29
KR20010034701A (ko) 2001-04-25
HK1035896A1 (en) 2001-12-14
US6437125B1 (en) 2002-08-20
JP2002510692A (ja) 2002-04-09
WO1999051604A2 (en) 1999-10-14
EP1068210B1 (en) 2004-06-02
BR9908959A (pt) 2000-12-05
CA2323965A1 (en) 1999-10-14
ES2222702T3 (es) 2005-02-01
EP1068210A2 (en) 2001-01-17
DE69917765T2 (de) 2005-07-14
CN1125068C (zh) 2003-10-22

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