ATE380171T1 - Verfahren zur herstellung von terbinafine - Google Patents
Verfahren zur herstellung von terbinafineInfo
- Publication number
- ATE380171T1 ATE380171T1 AT02003969T AT02003969T ATE380171T1 AT E380171 T1 ATE380171 T1 AT E380171T1 AT 02003969 T AT02003969 T AT 02003969T AT 02003969 T AT02003969 T AT 02003969T AT E380171 T1 ATE380171 T1 AT E380171T1
- Authority
- AT
- Austria
- Prior art keywords
- terbinafine
- producing
- reaction
- producing terbinafine
- butylacetylene
- Prior art date
Links
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 title abstract 2
- 229960002722 terbinafine Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
- PPWNCLVNXGCGAF-UHFFFAOYSA-N 3,3-dimethylbut-1-yne Chemical group CC(C)(C)C#C PPWNCLVNXGCGAF-UHFFFAOYSA-N 0.000 abstract 1
- VMQMZMRVKUZKQL-UHFFFAOYSA-N Cu+ Chemical class [Cu+] VMQMZMRVKUZKQL-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052763 palladium Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001MI000430A ITMI20010430A1 (it) | 2001-03-02 | 2001-03-02 | Metodo per la sintesi di terbinafina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE380171T1 true ATE380171T1 (de) | 2007-12-15 |
Family
ID=11447087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02003969T ATE380171T1 (de) | 2001-03-02 | 2002-02-22 | Verfahren zur herstellung von terbinafine |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6515181B2 (de) |
| EP (1) | EP1236709B1 (de) |
| JP (1) | JP2002308835A (de) |
| AT (1) | ATE380171T1 (de) |
| CA (1) | CA2373813A1 (de) |
| DE (1) | DE60223862T2 (de) |
| IT (1) | ITMI20010430A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7244703B2 (en) * | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
| ITMI20022534A1 (it) * | 2002-11-29 | 2004-05-30 | Dinamite Dipharma S P A | Procedimento per la preparazione di terbinafina mediante l'uso di platino come catalizzatore. |
| US20050197512A1 (en) * | 2003-08-29 | 2005-09-08 | Ulrich Beutler | Purification process |
| GB0503942D0 (en) * | 2005-02-25 | 2005-04-06 | Novartis Ag | Purification process |
| GB0320312D0 (en) * | 2003-08-29 | 2003-10-01 | Novartis Ag | Purification process |
| EP1706128B1 (de) * | 2003-12-08 | 2010-07-21 | CPEX Pharmaceuticals, Inc. | Pharmazeutische zusammensetzungen und verfahren für die insulinbehandlung |
| ITMI20041154A1 (it) * | 2004-06-09 | 2004-09-09 | Italiana Sint Spa | Procedimento di sintesi di terbinafina e suoi derivati |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4755538A (en) * | 1987-04-14 | 1988-07-05 | The B. F. Goodrich Company | Skinless porous particle PVC resin and process for producing same |
| NZ280065A (en) * | 1995-09-20 | 1998-04-27 | Apotex Inc | Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives |
-
2001
- 2001-03-02 IT IT2001MI000430A patent/ITMI20010430A1/it unknown
-
2002
- 2002-02-22 AT AT02003969T patent/ATE380171T1/de not_active IP Right Cessation
- 2002-02-22 DE DE60223862T patent/DE60223862T2/de not_active Expired - Fee Related
- 2002-02-22 EP EP02003969A patent/EP1236709B1/de not_active Expired - Lifetime
- 2002-02-28 US US10/085,699 patent/US6515181B2/en not_active Expired - Fee Related
- 2002-02-28 CA CA002373813A patent/CA2373813A1/en not_active Abandoned
- 2002-03-01 JP JP2002056007A patent/JP2002308835A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE60223862D1 (de) | 2008-01-17 |
| EP1236709A2 (de) | 2002-09-04 |
| CA2373813A1 (en) | 2002-09-02 |
| EP1236709A3 (de) | 2003-11-26 |
| US6515181B2 (en) | 2003-02-04 |
| JP2002308835A (ja) | 2002-10-23 |
| US20020123651A1 (en) | 2002-09-05 |
| EP1236709B1 (de) | 2007-12-05 |
| ITMI20010430A1 (it) | 2002-09-02 |
| DE60223862T2 (de) | 2008-03-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |