ATE213492T1 - Verfahren zur herstellung von racemisch sertralin - Google Patents
Verfahren zur herstellung von racemisch sertralinInfo
- Publication number
- ATE213492T1 ATE213492T1 AT99420077T AT99420077T ATE213492T1 AT E213492 T1 ATE213492 T1 AT E213492T1 AT 99420077 T AT99420077 T AT 99420077T AT 99420077 T AT99420077 T AT 99420077T AT E213492 T1 ATE213492 T1 AT E213492T1
- Authority
- AT
- Austria
- Prior art keywords
- sertraline
- dichlorophenyl
- racemixed
- producing
- racemic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
- C07C209/28—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with other reducing agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/14—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9804270A FR2777000B1 (fr) | 1998-04-01 | 1998-04-01 | Procede de preparation de la sertraline racemique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE213492T1 true ATE213492T1 (de) | 2002-03-15 |
Family
ID=9524917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99420077T ATE213492T1 (de) | 1998-04-01 | 1999-03-26 | Verfahren zur herstellung von racemisch sertralin |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6262308B1 (de) |
| EP (1) | EP0947499B1 (de) |
| AT (1) | ATE213492T1 (de) |
| DE (1) | DE69900892T2 (de) |
| DK (1) | DK0947499T3 (de) |
| ES (1) | ES2172296T3 (de) |
| FR (1) | FR2777000B1 (de) |
| PT (1) | PT947499E (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1031500A (en) * | 1998-11-03 | 2000-05-22 | Dandy A/S | Sucrose fatty acid esters for use as increased release of active ingredients |
| DK174219B1 (da) * | 1999-10-27 | 2002-09-30 | Gea Farmaceutisk Fabrik As | Forbedret syntese af racemisk sertralin |
| US6723878B2 (en) | 2001-06-15 | 2004-04-20 | Orion Corporation Fermion | Method for preparing sertraline |
| HUP0500215A2 (hu) * | 2002-05-10 | 2005-06-28 | Jirí Stohandl | Eljárás szertralin előállítására |
| JP2007502329A (ja) | 2003-05-23 | 2007-02-08 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | セルトラリン組成物 |
| KR101340270B1 (ko) | 2011-11-10 | 2013-12-10 | 보령제약 주식회사 | (+)-시스-서트랄린의 선택적인 제조방법 |
| CN109810004A (zh) * | 2017-11-20 | 2019-05-28 | 浙江京新药业股份有限公司 | 一种盐酸舍曲林杂质的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
| FR2632633B1 (fr) | 1988-06-08 | 1991-04-05 | Delalande Sa | Procede de preparation de 4-aryl-1-tetralones |
| GB9114947D0 (en) * | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline |
| GB9114948D0 (en) * | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
-
1998
- 1998-04-01 FR FR9804270A patent/FR2777000B1/fr not_active Expired - Fee Related
-
1999
- 1999-03-26 DE DE69900892T patent/DE69900892T2/de not_active Expired - Fee Related
- 1999-03-26 DK DK99420077T patent/DK0947499T3/da active
- 1999-03-26 EP EP99420077A patent/EP0947499B1/de not_active Expired - Lifetime
- 1999-03-26 PT PT99420077T patent/PT947499E/pt unknown
- 1999-03-26 AT AT99420077T patent/ATE213492T1/de not_active IP Right Cessation
- 1999-03-26 ES ES99420077T patent/ES2172296T3/es not_active Expired - Lifetime
- 1999-03-29 US US09/280,673 patent/US6262308B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69900892D1 (de) | 2002-03-28 |
| EP0947499A2 (de) | 1999-10-06 |
| DE69900892T2 (de) | 2002-09-19 |
| US6262308B1 (en) | 2001-07-17 |
| PT947499E (pt) | 2002-07-31 |
| ES2172296T3 (es) | 2002-09-16 |
| EP0947499A3 (de) | 2000-02-23 |
| FR2777000B1 (fr) | 2002-09-27 |
| FR2777000A1 (fr) | 1999-10-08 |
| DK0947499T3 (da) | 2002-06-10 |
| EP0947499B1 (de) | 2002-02-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |