RU93004462A - Способ стереоселективного синтеза хиральных аминов - Google Patents
Способ стереоселективного синтеза хиральных аминовInfo
- Publication number
- RU93004462A RU93004462A RU93004462/13A RU93004462A RU93004462A RU 93004462 A RU93004462 A RU 93004462A RU 93004462/13 A RU93004462/13 A RU 93004462/13A RU 93004462 A RU93004462 A RU 93004462A RU 93004462 A RU93004462 A RU 93004462A
- Authority
- RU
- Russia
- Prior art keywords
- stereoselective synthesis
- chiral amines
- chiral
- amines
- stereoselective
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title claims 2
- 230000015572 biosynthetic process Effects 0.000 title claims 2
- 230000000707 stereoselective Effects 0.000 title claims 2
- 238000003786 synthesis reaction Methods 0.000 title claims 2
- 230000002194 synthesizing Effects 0.000 title claims 2
- 150000002576 ketones Chemical class 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
Claims (1)
- Изобретение касается способа стереоселективного синтеза одной хиральной формы амина в количестве, существенно превосходящем другую форму, путем воздействия на кетон омега-аминокислотной трансаминазой в присутствии донора аминогруппы.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US369723 | 1989-06-22 | ||
US07/369,723 US4950606A (en) | 1989-06-22 | 1989-06-22 | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU4830607 Division |
Publications (2)
Publication Number | Publication Date |
---|---|
RU93004462A true RU93004462A (ru) | 1996-07-27 |
RU2116347C1 RU2116347C1 (ru) | 1998-07-27 |
Family
ID=23456647
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU93004462A RU2116347C1 (ru) | 1989-06-22 | 1990-06-21 | Способ стереоселективного синтеза хиральных аминов |
SU904830607A RU2087536C1 (ru) | 1989-06-22 | 1990-06-21 | Способ энантиомерного обогащения смеси двух энантиомерных хиральных аминов |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU904830607A RU2087536C1 (ru) | 1989-06-22 | 1990-06-21 | Способ энантиомерного обогащения смеси двух энантиомерных хиральных аминов |
Country Status (18)
Country | Link |
---|---|
US (1) | US4950606A (ru) |
EP (1) | EP0404146B1 (ru) |
JP (1) | JP2846074B2 (ru) |
KR (1) | KR0147827B1 (ru) |
AT (1) | ATE135744T1 (ru) |
AU (1) | AU628183B2 (ru) |
CA (1) | CA2018773C (ru) |
DE (1) | DE69025988T2 (ru) |
DK (1) | DK0404146T3 (ru) |
ES (1) | ES2084618T3 (ru) |
GR (1) | GR3019682T3 (ru) |
HK (1) | HK1008052A1 (ru) |
HU (1) | HU210967B (ru) |
IE (1) | IE72956B1 (ru) |
IL (1) | IL94694A (ru) |
NZ (1) | NZ234154A (ru) |
RU (2) | RU2116347C1 (ru) |
ZA (1) | ZA904571B (ru) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3842025A1 (de) * | 1988-12-14 | 1990-07-05 | Hoechst Ag | Verfahren zur herstellung von l-phosphinothricin |
US5169780A (en) * | 1989-06-22 | 1992-12-08 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
US5141904A (en) * | 1991-02-15 | 1992-08-25 | Phillips Petroleum Company | Reactivation of spent cracking catalysts |
CA2077400A1 (en) * | 1991-10-08 | 1993-04-09 | Mikhail Leyderman | Mandrel and a method of making a rigid tubular article |
US5439873A (en) * | 1994-02-23 | 1995-08-08 | Plant Growth Development Corporation | Method for stimulating plant growth using GABA |
US5840656A (en) * | 1994-02-23 | 1998-11-24 | Auxein Corporation | Method for increasing fertilizer efficiency |
US6534446B1 (en) | 1994-02-23 | 2003-03-18 | Emerald Bioagriculture Corporation | Method to mitigate plant stress |
EP0857790B1 (en) | 1995-10-23 | 2005-08-17 | Kaneka Corporation | Process for producing optically active amino compounds |
JPH10165194A (ja) * | 1996-12-12 | 1998-06-23 | Sumitomo Chem Co Ltd | 光学純度の向上方法 |
DE69841075D1 (de) * | 1997-04-23 | 2009-10-01 | Kaneka Corp | Deoxynukleinsäure welche ein Polypeptid mit stereoselektiver Transaminase Aktivität kodiert, sowie die Deoxynukleinsäure enthaltende Transformanden |
EP1045025B1 (en) | 1998-10-30 | 2008-10-22 | Kaneka Corporation | (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE |
US6432688B1 (en) | 1999-01-18 | 2002-08-13 | Daicel Chemical Industries, Ltd. | Amino alcohol dehydrogenase converts keto alcohol to amino alcohol and amino alcohol to keto alcohol |
JP4496593B2 (ja) * | 1999-03-19 | 2010-07-07 | 住友化学株式会社 | 蛋白質、その遺伝子及びその利用 |
EP1038953B1 (en) | 1999-03-19 | 2004-09-22 | Sumitomo Chemical Company, Limited | Stereoselective transaminase, gene encoding said protein and use thereof |
US6252114B1 (en) * | 2000-03-24 | 2001-06-26 | Council Of Scientific And Industrial Research | Process for preparing novel biologically active synthetic molecule 4-(p-methoxyphenyl)-2-amino-butane |
US7067291B2 (en) * | 2002-12-20 | 2006-06-27 | Pfizer Inc. | Biocatalytic preparation of enantiomerically enriched aminopentanenitrile |
US20050009151A1 (en) * | 2003-07-10 | 2005-01-13 | Pharmacia Corporation | Methods for the stereospecific and enantiomeric enrichment of beta-amino acids |
US7172885B2 (en) * | 2004-12-10 | 2007-02-06 | Cambrex North Brunswick, Inc. | Thermostable omega-transaminases |
DE602006008934D1 (de) * | 2005-05-23 | 2009-10-15 | Kaneka Corp | Neue aminogruppentransferase, dafür codierendes gen und verfahren zur verwendung davon |
EP1818411A1 (en) * | 2006-02-13 | 2007-08-15 | Lonza AG | Process for the preparation of optically active chiral amines |
EP1897956A1 (en) * | 2006-09-06 | 2008-03-12 | Lonza AG | Process for preparation of optically active amines by optical resolution of racemic amines employing a bacterial omega-transaminase |
JP5253372B2 (ja) | 2007-02-27 | 2013-07-31 | マニー株式会社 | かしめ装置 |
DE102007042600A1 (de) | 2007-09-07 | 2009-03-12 | Evonik Degussa Gmbh | Verfahren zur Herstellung von enantiomerenangereichten Aminen |
AU2009249306B8 (en) * | 2008-05-22 | 2013-07-25 | Merck Canada Inc. | Process for the preparation of an orexin receptor antagonist |
DK2385983T3 (en) | 2009-01-08 | 2018-02-12 | Codexis Inc | Transaminase POLYPEPTIDES |
DE102009000592A1 (de) | 2009-02-04 | 2010-08-05 | Evonik Degussa Gmbh | Verfahren zur Herstellung von Aminogruppen tragenden, multizyklischen Ringsystemen |
ES2448816T3 (es) * | 2009-02-26 | 2014-03-17 | Codexis, Inc. | Biocatalizadores de transaminasa |
SG177329A1 (en) | 2009-06-22 | 2012-02-28 | Codexis Inc | Transaminase reactions |
WO2011159910A2 (en) | 2010-06-17 | 2011-12-22 | Codexis, Inc. | Biocatalysts and methods for the synthesis of (s)-3-(1-aminoethyl)-phenol |
EP2606139B1 (en) | 2010-08-16 | 2015-07-15 | Codexis, Inc. | Biocatalysts and methods for the synthesis of (1r,2r)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine |
WO2014060571A1 (en) * | 2012-10-18 | 2014-04-24 | Sandoz Ag | A process for preparing indoline derivatives |
JP6618180B2 (ja) | 2012-12-21 | 2019-12-11 | コデクシス, インコーポレイテッド | キラルアミンを合成するための操作された生体触媒および方法 |
CN115927231A (zh) | 2013-02-28 | 2023-04-07 | 科德克希思公司 | 用于工业生物催化的工程化转氨酶多肽 |
US11359183B2 (en) | 2017-06-14 | 2022-06-14 | Codexis, Inc. | Engineered transaminase polypeptides for industrial biocatalysis |
KR20190109696A (ko) | 2018-03-18 | 2019-09-26 | 양만주 | 재사용이 가능한 페트병 홀더 |
TW202020148A (zh) | 2018-07-31 | 2020-06-01 | 德商拜耳廠股份有限公司 | 編碼改良之轉胺酶蛋白質之核酸 |
IL296841A (en) | 2020-04-10 | 2022-11-01 | Codexis Inc | Transaminase transaminase polypeptides |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3871958A (en) * | 1972-03-04 | 1975-03-18 | Ajinomoto Kk | Biological method of producing serine and serinol derivatives |
JPS6339237B2 (ru) * | 1979-04-06 | 1988-08-04 | Karuruberugu Baiotekunorojii Ltd As | |
JPS55138389A (en) * | 1979-04-14 | 1980-10-29 | Denki Kagaku Kogyo Kk | Preparation of amino alcohols |
JPS58198296A (ja) * | 1982-05-12 | 1983-11-18 | Chisso Corp | d−2−アミノブタノ−ルの製造法 |
JPS5939294A (ja) * | 1982-08-27 | 1984-03-03 | Hamari Yakuhin Kogyo Kk | 光学活性2−アミノ−1−ブタノ−ルの製造法 |
HU193902B (en) * | 1983-09-01 | 1987-12-28 | Genetics Inst | Process for preparing l-amino acids by means of transamination |
IT1191638B (it) * | 1985-10-31 | 1988-03-23 | Montedison Spa | Processo per la separazione enzimatica degli isomeri ottici del 2-amminobutanolo |
US4620861A (en) * | 1985-11-04 | 1986-11-04 | Corning Glass Works | Method for making index-profiled optical device |
IT1188641B (it) * | 1986-03-28 | 1988-01-20 | Montedison Spa | Processo per la risoluzione enzimatica di 2-ammino-1-alcanoli racemi |
JPS63237796A (ja) * | 1987-03-25 | 1988-10-04 | Kanegafuchi Chem Ind Co Ltd | 光学活性1−メチル−3−フエニルプロピルアミンの製造法 |
JPS63273486A (ja) * | 1987-04-30 | 1988-11-10 | Tanabe Seiyaku Co Ltd | 1−(4−メトキシフェニル)−2−アミノプロパンの製法 |
DE3818851A1 (de) * | 1988-06-03 | 1989-12-14 | Hoechst Ag | Neue transaminase, ihre herstellung und ihre verwendung |
-
1989
- 1989-06-22 US US07/369,723 patent/US4950606A/en not_active Expired - Lifetime
-
1990
- 1990-06-11 IL IL9469490A patent/IL94694A/en active IP Right Grant
- 1990-06-12 CA CA002018773A patent/CA2018773C/en not_active Expired - Lifetime
- 1990-06-13 ZA ZA904571A patent/ZA904571B/xx unknown
- 1990-06-14 IE IE215990A patent/IE72956B1/en not_active IP Right Cessation
- 1990-06-19 AU AU57541/90A patent/AU628183B2/en not_active Expired
- 1990-06-20 NZ NZ234154A patent/NZ234154A/xx unknown
- 1990-06-21 HU HU903945A patent/HU210967B/hu unknown
- 1990-06-21 EP EP90111754A patent/EP0404146B1/en not_active Expired - Lifetime
- 1990-06-21 DE DE69025988T patent/DE69025988T2/de not_active Expired - Lifetime
- 1990-06-21 ES ES90111754T patent/ES2084618T3/es not_active Expired - Lifetime
- 1990-06-21 RU RU93004462A patent/RU2116347C1/ru active
- 1990-06-21 RU SU904830607A patent/RU2087536C1/ru active
- 1990-06-21 AT AT90111754T patent/ATE135744T1/de not_active IP Right Cessation
- 1990-06-21 DK DK90111754.9T patent/DK0404146T3/da active
- 1990-06-22 JP JP2165480A patent/JP2846074B2/ja not_active Expired - Lifetime
- 1990-06-22 KR KR1019900009317A patent/KR0147827B1/ko not_active IP Right Cessation
-
1996
- 1996-04-19 GR GR960401061T patent/GR3019682T3/el unknown
-
1998
- 1998-06-27 HK HK98107175A patent/HK1008052A1/xx not_active IP Right Cessation
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