DE602006008934D1 - Neue aminogruppentransferase, dafür codierendes gen und verfahren zur verwendung davon - Google Patents

Neue aminogruppentransferase, dafür codierendes gen und verfahren zur verwendung davon

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Publication number
DE602006008934D1
DE602006008934D1 DE602006008934T DE602006008934T DE602006008934D1 DE 602006008934 D1 DE602006008934 D1 DE 602006008934D1 DE 602006008934 T DE602006008934 T DE 602006008934T DE 602006008934 T DE602006008934 T DE 602006008934T DE 602006008934 D1 DE602006008934 D1 DE 602006008934D1
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DE
Germany
Prior art keywords
aminogruppentransferase
therefor
new
code generating
code
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006008934T
Other languages
English (en)
Inventor
Noriyuki Ito
Yoshihiko Yasohara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaneka Corp
Original Assignee
Kaneka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaneka Corp filed Critical Kaneka Corp
Publication of DE602006008934D1 publication Critical patent/DE602006008934D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/008—Preparation of nitrogen-containing organic compounds containing a N-O bond, e.g. nitro (-NO2), nitroso (-NO)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE602006008934T 2005-05-23 2006-05-22 Neue aminogruppentransferase, dafür codierendes gen und verfahren zur verwendung davon Active DE602006008934D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005149900 2005-05-23
PCT/JP2006/310170 WO2006126498A1 (ja) 2005-05-23 2006-05-22 新規アミノ基転移酵素、およびこれをコードする遺伝子、ならびにこれらの利用法

Publications (1)

Publication Number Publication Date
DE602006008934D1 true DE602006008934D1 (de) 2009-10-15

Family

ID=37451924

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006008934T Active DE602006008934D1 (de) 2005-05-23 2006-05-22 Neue aminogruppentransferase, dafür codierendes gen und verfahren zur verwendung davon

Country Status (5)

Country Link
US (2) US8133705B2 (de)
EP (1) EP1889907B1 (de)
JP (1) JP4922929B2 (de)
DE (1) DE602006008934D1 (de)
WO (1) WO2006126498A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1818411A1 (de) 2006-02-13 2007-08-15 Lonza AG Verfahren zur Herstellung von optisch aktiven chiralen Aminen
EP1897956A1 (de) * 2006-09-06 2008-03-12 Lonza AG Verfahren zur Herstellung von optisch aktiven Aminen durch Racematspaltung unter Verwendung einer bakteriellen omega-Transaminase
KR101489267B1 (ko) 2007-12-27 2015-02-04 도오레 화인케미칼 가부시키가이샤 광학 활성 3-아미노피롤리딘염, 그 제조 방법 및 3-아미노피롤리딘의 광학 분할 방법
DK3354727T3 (da) 2009-01-08 2020-11-16 Codexis Inc Transaminasepolypeptider
EP2401366B1 (de) 2009-02-26 2013-12-18 Codexis, Inc. Transaminase-biokatalysatoren
WO2011005477A1 (en) 2009-06-22 2011-01-13 Codexis, Inc. Transaminase reactions
US8852900B2 (en) 2010-06-17 2014-10-07 Codexis, Inc. Biocatalysts and methods for the synthesis of (S)-3-(1-aminoethyl)-phenol
WO2012024104A2 (en) * 2010-08-16 2012-02-23 Codexis, Inc. Biocatalysts and methods for the synthesis of (1r,2r)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
EP2623593B1 (de) * 2010-09-28 2017-07-12 Kaneka Corporation Neue aminotransferase und dafür kodierendes gen sowie verwendung der aminotransferase und des gens
JP5936545B2 (ja) * 2010-09-28 2016-06-22 株式会社カネカ グルタミン酸に高活性を示す新規アミノ基転移酵素、およびこれをコードする遺伝子、ならびにこれらの利用法
CN103534353B (zh) * 2011-03-11 2016-08-17 株式会社钟化 修饰型氨基转移酶、其基因以及利用它们的光学活性氨基化合物的制造方法
CN102731326B (zh) * 2011-04-01 2014-07-23 安徽省科隆药物研究所 一种合成（s）-2-氨基-5-甲氧基-1,2,3,4-四氢萘盐酸盐的方法
CN106053657B (zh) * 2016-07-01 2018-12-04 东北制药集团股份有限公司 一种采用高效液相色谱检测手性苯乙胺含量的方法
CN105987894B (zh) * 2016-07-06 2019-03-05 天津大学 酶偶联核酸-银纳米的探针在检测d-氨基酸的应用
CN106018371B (zh) * 2016-07-06 2019-02-15 天津大学 酶偶联核酸-银纳米探针
CN114277011B (zh) * 2021-12-29 2024-02-06 凯莱英医药集团（天津）股份有限公司 转氨酶突变体及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950606A (en) 1989-06-22 1990-08-21 Celgene Corporation Enantiomeric enrichment and stereoselective synthesis of chiral amines
JP3078137B2 (ja) 1992-12-15 2000-08-21 株式会社トクヤマ ベンジルアミントランスアミナーゼ
DE69635082T2 (de) 1995-10-23 2006-06-01 Kaneka Corp. Verfahren zur herstellung optisch aktiver aminoverbindungen
WO1998048030A1 (fr) 1997-04-23 1998-10-29 Kaneka Corporation Procede d'elaboration de composes amino optiquement actifs
ATE412047T1 (de) 1998-10-30 2008-11-15 Kaneka Corp (s)-alpha-phenethylamin: pyruvattransaminase
JP3870690B2 (ja) * 2000-09-01 2007-01-24 三菱化学株式会社 光学活性アミン類の製造方法
AU2002306849A1 (en) * 2001-03-21 2002-10-08 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms

Also Published As

Publication number Publication date
EP1889907B1 (de) 2009-09-02
EP1889907A4 (de) 2008-07-02
US20100285544A1 (en) 2010-11-11
JPWO2006126498A1 (ja) 2008-12-25
US20120164724A1 (en) 2012-06-28
US8431378B2 (en) 2013-04-30
US8133705B2 (en) 2012-03-13
EP1889907A1 (de) 2008-02-20
WO2006126498A1 (ja) 2006-11-30
JP4922929B2 (ja) 2012-04-25

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