DK0947499T3 - Fremgangsmåde til fremstilling af racemisk sertralin - Google Patents
Fremgangsmåde til fremstilling af racemisk sertralinInfo
- Publication number
- DK0947499T3 DK0947499T3 DK99420077T DK99420077T DK0947499T3 DK 0947499 T3 DK0947499 T3 DK 0947499T3 DK 99420077 T DK99420077 T DK 99420077T DK 99420077 T DK99420077 T DK 99420077T DK 0947499 T3 DK0947499 T3 DK 0947499T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- dichlorophenyl
- racemic
- sertraline
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
- C07C209/28—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with other reducing agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/14—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9804270A FR2777000B1 (fr) | 1998-04-01 | 1998-04-01 | Procede de preparation de la sertraline racemique |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0947499T3 true DK0947499T3 (da) | 2002-06-10 |
Family
ID=9524917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99420077T DK0947499T3 (da) | 1998-04-01 | 1999-03-26 | Fremgangsmåde til fremstilling af racemisk sertralin |
Country Status (8)
Country | Link |
---|---|
US (1) | US6262308B1 (da) |
EP (1) | EP0947499B1 (da) |
AT (1) | ATE213492T1 (da) |
DE (1) | DE69900892T2 (da) |
DK (1) | DK0947499T3 (da) |
ES (1) | ES2172296T3 (da) |
FR (1) | FR2777000B1 (da) |
PT (1) | PT947499E (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1031500A (en) * | 1998-11-03 | 2000-05-22 | Dandy A/S | Sucrose fatty acid esters for use as increased release of active ingredients |
DK174219B1 (da) * | 1999-10-27 | 2002-09-30 | Gea Farmaceutisk Fabrik As | Forbedret syntese af racemisk sertralin |
US6723878B2 (en) | 2001-06-15 | 2004-04-20 | Orion Corporation Fermion | Method for preparing sertraline |
WO2003099761A1 (en) * | 2002-05-10 | 2003-12-04 | Stohandl Jiri | Process for the manufacture of sertraline |
JP2007502329A (ja) | 2003-05-23 | 2007-02-08 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | セルトラリン組成物 |
KR101340270B1 (ko) | 2011-11-10 | 2013-12-10 | 보령제약 주식회사 | (+)-시스-서트랄린의 선택적인 제조방법 |
CN109810004A (zh) * | 2017-11-20 | 2019-05-28 | 浙江京新药业股份有限公司 | 一种盐酸舍曲林杂质的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4536518A (en) * | 1979-11-01 | 1985-08-20 | Pfizer Inc. | Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
FR2632633B1 (fr) | 1988-06-08 | 1991-04-05 | Delalande Sa | Procede de preparation de 4-aryl-1-tetralones |
GB9114948D0 (en) * | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline intermediates |
GB9114947D0 (en) * | 1991-07-11 | 1991-08-28 | Pfizer Ltd | Process for preparing sertraline |
-
1998
- 1998-04-01 FR FR9804270A patent/FR2777000B1/fr not_active Expired - Fee Related
-
1999
- 1999-03-26 ES ES99420077T patent/ES2172296T3/es not_active Expired - Lifetime
- 1999-03-26 AT AT99420077T patent/ATE213492T1/de not_active IP Right Cessation
- 1999-03-26 PT PT99420077T patent/PT947499E/pt unknown
- 1999-03-26 DE DE69900892T patent/DE69900892T2/de not_active Expired - Fee Related
- 1999-03-26 EP EP99420077A patent/EP0947499B1/fr not_active Expired - Lifetime
- 1999-03-26 DK DK99420077T patent/DK0947499T3/da active
- 1999-03-29 US US09/280,673 patent/US6262308B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2777000B1 (fr) | 2002-09-27 |
PT947499E (pt) | 2002-07-31 |
EP0947499A3 (fr) | 2000-02-23 |
ES2172296T3 (es) | 2002-09-16 |
EP0947499B1 (fr) | 2002-02-20 |
EP0947499A2 (fr) | 1999-10-06 |
FR2777000A1 (fr) | 1999-10-08 |
DE69900892T2 (de) | 2002-09-19 |
DE69900892D1 (de) | 2002-03-28 |
ATE213492T1 (de) | 2002-03-15 |
US6262308B1 (en) | 2001-07-17 |
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