EP1288215B8 - Production method of famciclovir and production and crystallization method of intermediate therefor - Google Patents
Production method of famciclovir and production and crystallization method of intermediate therefor Download PDFInfo
- Publication number
- EP1288215B8 EP1288215B8 EP02019301A EP02019301A EP1288215B8 EP 1288215 B8 EP1288215 B8 EP 1288215B8 EP 02019301 A EP02019301 A EP 02019301A EP 02019301 A EP02019301 A EP 02019301A EP 1288215 B8 EP1288215 B8 EP 1288215B8
- Authority
- EP
- European Patent Office
- Prior art keywords
- production
- famciclovir
- intermediate therefor
- crystallization
- crystallization method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001262301 | 2001-08-30 | ||
JP2001262301 | 2001-08-30 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1288215A1 EP1288215A1 (en) | 2003-03-05 |
EP1288215B1 EP1288215B1 (en) | 2004-12-15 |
EP1288215B8 true EP1288215B8 (en) | 2005-04-06 |
Family
ID=19089217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02019301A Expired - Lifetime EP1288215B8 (en) | 2001-08-30 | 2002-08-28 | Production method of famciclovir and production and crystallization method of intermediate therefor |
Country Status (3)
Country | Link |
---|---|
US (1) | US6761767B2 (en) |
EP (1) | EP1288215B8 (en) |
DE (1) | DE60202245T2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2426247A (en) * | 2005-05-20 | 2006-11-22 | Arrow Int Ltd | Methods of preparing purine derivatives such as famciclovir |
WO2007037790A2 (en) * | 2005-06-08 | 2007-04-05 | Elan Corporation, Plc | Modified release famciclovir compositions |
EP1852435A1 (en) * | 2006-04-12 | 2007-11-07 | SOLMAG S.p.A. | A process for the manufacture of famciclovir using phase-transfer catalysts |
EP2170840A1 (en) * | 2007-06-21 | 2010-04-07 | Aurobindo Pharma Ltd | An improved process for preparing purine derivative |
CN108314685B (en) * | 2018-03-16 | 2020-08-25 | 上药康丽(常州)药业有限公司 | Preparation method of 2-amino-6-chloro-9- (4-acetoxyl-3-acetoxymethyl butyl) purine |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3906488B2 (en) | 1995-02-21 | 2007-04-18 | 味の素株式会社 | Method for producing purine derivatives |
EP0827960A1 (en) | 1996-09-10 | 1998-03-11 | Ajinomoto Co., Inc. | Process for producing purine derivatives |
CA2251481A1 (en) | 1997-11-12 | 1999-05-12 | Junichi Yasuoka | Purine derivatives having cyclopropane ring |
JPH11180983A (en) | 1997-12-24 | 1999-07-06 | Sumika Fine Chemicals Co Ltd | 9-substituted-2-amino-6-halogenopurine and its production |
GB9807116D0 (en) | 1998-04-02 | 1998-06-03 | Smithkline Beecham Plc | Novel process |
GB9807114D0 (en) | 1998-04-02 | 1998-06-03 | Smithkline Beecham Plc | Novel process |
SI20022A (en) | 1998-07-29 | 2000-02-29 | Kemijski inštitut | Alkyl substituted purine derivatives and their preparation |
-
2002
- 2002-08-28 DE DE60202245T patent/DE60202245T2/en not_active Expired - Fee Related
- 2002-08-28 EP EP02019301A patent/EP1288215B8/en not_active Expired - Lifetime
- 2002-08-30 US US10/231,249 patent/US6761767B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20030056712A1 (en) | 2003-03-27 |
DE60202245T2 (en) | 2005-09-01 |
US6761767B2 (en) | 2004-07-13 |
EP1288215A1 (en) | 2003-03-05 |
DE60202245D1 (en) | 2005-01-20 |
EP1288215B1 (en) | 2004-12-15 |
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