DK106552C - Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner. - Google Patents

Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner.

Info

Publication number
DK106552C
DK106552C DK626864A DK626864A DK106552C DK 106552 C DK106552 C DK 106552C DK 626864 A DK626864 A DK 626864A DK 626864 A DK626864 A DK 626864A DK 106552 C DK106552 C DK 106552C
Authority
DK
Denmark
Prior art keywords
benzomorphans
substituted
preparation
Prior art date
Application number
DK626864A
Other languages
Danish (da)
English (en)
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Application granted granted Critical
Publication of DK106552C publication Critical patent/DK106552C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/82Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22Bridged ring systems
    • C07D221/26Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Discharge Lamp (AREA)
DK626864A 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner. DK106552C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33229663A 1963-12-20 1963-12-20

Publications (1)

Publication Number Publication Date
DK106552C true DK106552C (da) 1967-02-20

Family

ID=23297612

Family Applications (4)

Application Number Title Priority Date Filing Date
DK429765A DK108496C (da) 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf.
DK429865A DK108497C (da) 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf.
DK626864A DK106552C (da) 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner.
DK626764A DK108495C (da) 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK429765A DK108496C (da) 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf.
DK429865A DK108497C (da) 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK626764A DK108495C (da) 1963-12-20 1964-12-19 Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf.

Country Status (12)

Country Link
AT (4) AT249276B (enrdf_load_html_response)
BE (2) BE657405A (enrdf_load_html_response)
CH (7) CH449639A (enrdf_load_html_response)
DE (2) DE1445854A1 (enrdf_load_html_response)
DK (4) DK108496C (enrdf_load_html_response)
ES (4) ES307302A1 (enrdf_load_html_response)
FR (2) FR4345M (enrdf_load_html_response)
GB (2) GB1092394A (enrdf_load_html_response)
IL (2) IL22643A (enrdf_load_html_response)
NL (3) NL6414821A (enrdf_load_html_response)
NO (2) NO119274B (enrdf_load_html_response)
SE (2) SE322779B (enrdf_load_html_response)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003234621A1 (en) 2002-05-17 2003-12-02 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7923454B2 (en) 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7501433B2 (en) 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
CA2678577A1 (en) 2007-02-26 2008-09-04 Vitae Pharmaceuticals, Inc. Cyclic urea and carbamate inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
JP5470557B2 (ja) 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ,インコーポレイテッド 11β−ヒドロキシステロイドデヒドロゲナーゼ1型の阻害剤の合成
AR069207A1 (es) 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
TW200927115A (en) 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
EP2252598A2 (en) 2008-02-11 2010-11-24 Vitae Pharmaceuticals, Inc. 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2711757C (en) * 2008-02-12 2016-07-26 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723032A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
PL2300461T3 (pl) 2008-05-01 2013-09-30 Vitae Pharmaceuticals Inc Cykliczne inhibitory dehydrogenazy 11beta-hydroksysteroidów 1
EP2291371B1 (en) 2008-05-01 2015-06-10 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8765780B2 (en) 2008-05-13 2014-07-01 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
US8846668B2 (en) 2008-07-25 2014-09-30 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ590495A (en) 2008-07-25 2012-10-26 Vitae Pharmaceuticals Inc Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR073920A1 (es) 2008-10-23 2010-12-09 Boehringer Ingelheim Int Derivados urea de nortropanos sustituidos, medicamentos que contienen dichos compuestos , su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa y proceso para su preparacion.
EP2393807B1 (en) 2009-02-04 2013-08-14 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2438049B1 (en) 2009-06-02 2014-05-14 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
WO2011002910A1 (en) 2009-07-01 2011-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
JP5813106B2 (ja) 2010-06-25 2015-11-17 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 代謝障害の処置のための11−β−HSD1のインヒビターとしてのアザスピロヘキサノン
MX2013004699A (es) 2010-11-02 2013-05-22 Boehringer Ingelheim Int Combinaciones farmaceuticas para el tratamiento de trastornos metabolicos.
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
BE657405A (enrdf_load_html_response) 1965-06-21
CH449640A (de) 1968-01-15
CH446371A (de) 1967-11-15
NL127995C (enrdf_load_html_response)
NO119273B (enrdf_load_html_response) 1970-04-27
DE1445854A1 (de) 1968-12-05
AT253687B (de) 1967-04-25
ES307299A1 (es) 1965-05-16
NL6414821A (enrdf_load_html_response) 1965-06-21
GB1092394A (en) 1967-11-22
CH448118A (de) 1967-12-15
NL6414820A (enrdf_load_html_response) 1965-06-21
DK108495C (da) 1967-12-27
GB1077711A (en) 1967-08-02
IL22643A (en) 1968-07-25
CH449639A (de) 1968-01-15
SE322779B (enrdf_load_html_response) 1970-04-20
ES307302A1 (es) 1965-05-16
AT249277B (de) 1966-09-12
CH449642A (de) 1968-01-15
AT261126B (de) 1968-04-10
DK108497C (da) 1967-12-27
CH449643A (de) 1968-01-15
FR4345M (enrdf_load_html_response) 1966-08-16
NO119274B (enrdf_load_html_response) 1970-04-27
FR4346M (enrdf_load_html_response) 1966-08-16
AT249276B (de) 1966-09-12
IL22642A (en) 1968-07-25
BE657406A (enrdf_load_html_response) 1965-06-21
DK108496C (da) 1967-12-27
ES307301A1 (es) 1965-05-16
CH449641A (de) 1968-01-15
DE1445853A1 (de) 1968-12-05
SE305657B (enrdf_load_html_response) 1968-11-04
ES307300A1 (es) 1965-05-01

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