DK1058542T3 - Fremgangsmåde til fremstilling af indkapslede sfærisk granulatkorn - Google Patents

Fremgangsmåde til fremstilling af indkapslede sfærisk granulatkorn

Info

Publication number
DK1058542T3
DK1058542T3 DK99908932T DK99908932T DK1058542T3 DK 1058542 T3 DK1058542 T3 DK 1058542T3 DK 99908932 T DK99908932 T DK 99908932T DK 99908932 T DK99908932 T DK 99908932T DK 1058542 T3 DK1058542 T3 DK 1058542T3
Authority
DK
Denmark
Prior art keywords
grains
encased
polymer dispersion
prostane
preparation
Prior art date
Application number
DK99908932T
Other languages
Danish (da)
English (en)
Inventor
Torsten Wagner
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK1058542T3 publication Critical patent/DK1058542T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glanulating (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK99908932T 1998-02-24 1999-02-24 Fremgangsmåde til fremstilling af indkapslede sfærisk granulatkorn DK1058542T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19808634A DE19808634A1 (de) 1998-02-24 1998-02-24 Mantel für eine pharmazeutische Zusammensetzung

Publications (1)

Publication Number Publication Date
DK1058542T3 true DK1058542T3 (da) 2006-01-02

Family

ID=7859315

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99908932T DK1058542T3 (da) 1998-02-24 1999-02-24 Fremgangsmåde til fremstilling af indkapslede sfærisk granulatkorn

Country Status (18)

Country Link
US (1) US6723372B1 (hu)
EP (1) EP1058542B1 (hu)
JP (1) JP2002504506A (hu)
KR (1) KR100623542B1 (hu)
AT (1) ATE303133T1 (hu)
AU (1) AU753261B2 (hu)
CA (1) CA2321969C (hu)
CZ (1) CZ299252B6 (hu)
DE (2) DE19808634A1 (hu)
DK (1) DK1058542T3 (hu)
ES (1) ES2247786T3 (hu)
HU (1) HU226066B1 (hu)
IL (1) IL137965A (hu)
NO (1) NO20004225L (hu)
PL (1) PL193071B1 (hu)
RU (1) RU2209060C2 (hu)
SK (1) SK284062B6 (hu)
WO (1) WO1999043303A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19828881A1 (de) 1998-06-22 1999-12-23 Schering Ag Oxidationsinhibitor bei Prostan-Derivaten
US8323692B2 (en) 2002-02-21 2012-12-04 Valeant International Bermuda Controlled release dosage forms
EP1479383B1 (en) * 2003-05-20 2006-10-04 Ethypharm Oral sustained release pharmaceutical composition
US8318230B2 (en) * 2005-05-02 2012-11-27 Henkel Ag & Co. Kgaa Use of debranched starch in extrusion-spheronization pharmaceutical pellets
EP1956013B1 (en) 2005-11-30 2016-04-13 Fujifilm RI Pharma Co., Ltd. Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition
RU2702690C2 (ru) * 2015-08-13 2019-10-09 БИОЛИНГУС АйПи ЛЛСи Способ получения продуктов, содержащих стабилизированные активные вещества, и композиций, содержащих таковые
CN106822013B (zh) * 2015-11-30 2020-05-12 北京泰德制药股份有限公司 前列环素类似物缓释制剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA935093A (en) * 1969-07-28 1973-10-09 Eurand S.R.L. Method of preparing granules with controlled release of the active substance contained therein
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3622487A1 (de) * 1986-07-02 1988-01-14 Schering Ag Arzneimittel mit verzoegerter wirkstoffabgabe
US5286494A (en) * 1986-07-02 1994-02-15 Schering Aktiengesellschaft Medicinal agents with sustained action
US5286493A (en) * 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
JP3277342B2 (ja) * 1992-09-02 2002-04-22 武田薬品工業株式会社 徐放性マイクロカプセルの製造法
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
US5376384A (en) * 1992-12-23 1994-12-27 Kinaform Technology, Inc. Delayed, sustained-release pharmaceutical preparation
FI94926C (fi) * 1993-11-12 1995-11-27 Leiras Oy Menetelmä klodronaattivalmisteen valmistamiseksi
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
JPH10139659A (ja) * 1996-09-10 1998-05-26 Freunt Ind Co Ltd 球形粒子群、その製造方法及びそれを用いた球形粒子製剤

Also Published As

Publication number Publication date
ES2247786T3 (es) 2006-03-01
EP1058542B1 (de) 2005-08-31
AU2835299A (en) 1999-09-15
DE19808634A1 (de) 1999-08-26
KR20010041210A (ko) 2001-05-15
CA2321969C (en) 2007-04-10
EP1058542A1 (de) 2000-12-13
CZ299252B6 (cs) 2008-05-28
HUP0100752A2 (hu) 2001-08-28
ATE303133T1 (de) 2005-09-15
KR100623542B1 (ko) 2006-09-13
AU753261B2 (en) 2002-10-10
DE59912501D1 (de) 2005-10-06
NO20004225L (no) 2000-09-28
RU2209060C2 (ru) 2003-07-27
CA2321969A1 (en) 1999-09-02
HU226066B1 (en) 2008-04-28
IL137965A0 (en) 2001-10-31
NO20004225D0 (no) 2000-08-23
IL137965A (en) 2005-11-20
CZ20003088A3 (cs) 2000-11-15
PL342315A1 (en) 2001-06-04
SK284062B6 (sk) 2004-09-08
JP2002504506A (ja) 2002-02-12
US6723372B1 (en) 2004-04-20
WO1999043303A1 (de) 1999-09-02
SK12422000A3 (sk) 2001-04-09
PL193071B1 (pl) 2007-01-31

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