DK105680A - Fremgangsmaade til fremstilling af peptider - Google Patents

Fremgangsmaade til fremstilling af peptider

Info

Publication number
DK105680A
DK105680A DK105680A DK105680A DK105680A DK 105680 A DK105680 A DK 105680A DK 105680 A DK105680 A DK 105680A DK 105680 A DK105680 A DK 105680A DK 105680 A DK105680 A DK 105680A
Authority
DK
Denmark
Prior art keywords
image
tyr
inhibiting
release
peptides
Prior art date
Application number
DK105680A
Other languages
Danish (da)
English (en)
Inventor
D F Veber
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK105680A publication Critical patent/DK105680A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK105680A 1979-03-13 1980-03-12 Fremgangsmaade til fremstilling af peptider DK105680A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/020,148 US4190648A (en) 1979-03-13 1979-03-13 Peptides having somatostatin activity

Publications (1)

Publication Number Publication Date
DK105680A true DK105680A (da) 1980-09-14

Family

ID=21797013

Family Applications (1)

Application Number Title Priority Date Filing Date
DK105680A DK105680A (da) 1979-03-13 1980-03-12 Fremgangsmaade til fremstilling af peptider

Country Status (6)

Country Link
US (1) US4190648A (de)
EP (1) EP0017746B1 (de)
JP (1) JPS55124747A (de)
AT (1) ATE2318T1 (de)
DE (1) DE3061721D1 (de)
DK (1) DK105680A (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310518A (en) * 1979-10-31 1982-01-12 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs
CY1327A (en) * 1979-11-27 1986-06-27 Sandoz Ag Novel polypeptides,processes for their production,pharmaceutical compositions comprising said polypeptides and their use
US4358439A (en) * 1979-12-21 1982-11-09 Ciba-Geigy Corporation Cyclooctapeptides
US4360516A (en) * 1981-04-13 1982-11-23 Merck & Co., Inc. Modified D-retro cyclic hexapeptide somatostatin analogs
DE3379657D1 (en) * 1982-12-06 1989-05-24 Merck & Co Inc Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them
US4871717A (en) * 1987-01-07 1989-10-03 Administrators Of The Tulane Educational Fund Peptides
US4994554A (en) * 1988-05-11 1991-02-19 Immunobiology Research Institute, Inc. Probursin
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
ATE245998T1 (de) 1997-05-13 2003-08-15 Sod Conseils Rech Applic Somatostatin agoniste zur reduzierung von körpergewicht
DK0980253T3 (da) * 1997-05-13 2004-07-05 Sod Conseils Rech Applic Somatostatin og somatostatinagonister til behandling af insulininsensitivitet og syndrom X
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
WO1998051330A1 (en) * 1997-05-13 1998-11-19 Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) Method and compositions for treating hyperlipidemia and other conditions
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
CZ305160B6 (cs) 2001-06-08 2015-05-27 Ipsen Pharma S.A.S. Chimérické somatostatin-dopaminové analogy
CN101791409A (zh) 2003-04-22 2010-08-04 研究及应用科学协会股份有限公司 肽载体
BRPI0915142A8 (pt) 2008-06-12 2018-01-02 Syntaxin Ltd Polipeptídeos, ácido nucleico e usos dos mesmos
EP3590956A1 (de) 2008-06-12 2020-01-08 Ipsen Bioinnovation Limited Unterdrückung von neuroendokrinen erkrankungen
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000053B1 (de) * 1977-06-08 1981-05-27 Merck & Co. Inc. Somatostatin-ähnliche Verbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
US4140767A (en) * 1977-12-01 1979-02-20 Merck & Co., Inc. Somatostatin analogs
US4139526A (en) * 1977-12-01 1979-02-13 Merck & Co., Inc. Somatostatin analogs

Also Published As

Publication number Publication date
EP0017746B1 (de) 1983-01-26
JPS55124747A (en) 1980-09-26
DE3061721D1 (en) 1983-03-03
US4190648A (en) 1980-02-26
ATE2318T1 (de) 1983-02-15
EP0017746A1 (de) 1980-10-29

Similar Documents

Publication Publication Date Title
DK105680A (da) Fremgangsmaade til fremstilling af peptider
IE781151L (en) Somatostatin analogs
US4563352A (en) Human pancreatic GRF
US4435385A (en) N-Acyl-polypeptides and processes for the production thereof
JPH0133118B2 (de)
DK165749B (da) Grf-analoge peptider og farmaceutisk acceptable salte heraf samt farmaceutisk middel indeholdende disse
ZA926337B (en) Polypeptide analogues having growth hormone releasing activity.
HUT63855A (en) Process for producing salts of lh-rh analogous compounds and pharmaceutical compositions comprising such salts
DK169784D0 (da) Peptider til farmaceutisk behandling af pattedyr
KR927002373A (ko) 성장 호르몬 분비 활성을 갖는 폴리펩타이드 화합물
KR900006560B1 (ko) Grf 유사체의 제법
ES8202787A1 (es) Un procedimiento para la preparacion de un hexapeptido ci- clico
IE781724L (en) Peptides
AU646451B2 (en) Hybrid calcitonin
KR0163033B1 (ko) Grf 유사체 viia
EP0107890B1 (de) PGRF von Säugetieren
US4011207A (en) Des-(Ala1, Gly2,Lys4 -Srif, Des-(Ala1, Gly2, Lys4)-D-Trp8 -Srif and intermediates
US4393050A (en) Analogs of extended N-terminal somatostatin
US4816438A (en) Insulin-selective somatostatin analogs
CA1333892C (en) Insulin-selective somatostatin analogs
KR920019817A (ko) 초활성 grf 유사체
KR880013970A (ko) 신규한 알킬화 성장 호르몬-방출 펩티드와 그것으로 포유동물을 처리하는 방법
JPS5791965A (en) Preparation of polypeptide
JPH04210998A (ja) ペプチド誘導体による消化管の内皮イオン分泌の抑制
Sarantakis et al. Des-(Ala 1, Gly 2), Met 11-SRIF and intermediates