JPS5791965A - Preparation of polypeptide - Google Patents

Preparation of polypeptide

Info

Publication number
JPS5791965A
JPS5791965A JP56140117A JP14011781A JPS5791965A JP S5791965 A JPS5791965 A JP S5791965A JP 56140117 A JP56140117 A JP 56140117A JP 14011781 A JP14011781 A JP 14011781A JP S5791965 A JPS5791965 A JP S5791965A
Authority
JP
Japan
Prior art keywords
polypeptide
amino acid
pituitary
agent
pyroglutamic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56140117A
Other languages
Japanese (ja)
Other versions
JPS5824428B2 (en
Inventor
Masahiko Fujino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP56140117A priority Critical patent/JPS5824428B2/en
Publication of JPS5791965A publication Critical patent/JPS5791965A/en
Publication of JPS5824428B2 publication Critical patent/JPS5824428B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:The polypeptide of formulaI(R is lower alkyl which may be substituted with OH; Ala is D-isomer and the others are L-amino acid).
EXAMPLE: The polypeptide of formula II.
USE: Ovulation inducing agent for diagnosis of pituitary function, and remedy for hypopituitarism. The agent stimmulates the pituitary and promotes the section of luteinizing hormone and follicule-stimulating hormone. The compound has extremely low toxicity, and can be administered safely.
PROCESS: The polypeptide of formulaIis prepared by condensing pyroglutamic acid or a partial peptide having the amino acid sequence corresponding to formulaIand having pyroglutamic acid residue as the N-terminal, with the residual part of the polypeptide of tormulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP56140117A 1981-09-04 1981-09-04 Method for producing polypeptides Expired JPS5824428B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56140117A JPS5824428B2 (en) 1981-09-04 1981-09-04 Method for producing polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56140117A JPS5824428B2 (en) 1981-09-04 1981-09-04 Method for producing polypeptides

Publications (2)

Publication Number Publication Date
JPS5791965A true JPS5791965A (en) 1982-06-08
JPS5824428B2 JPS5824428B2 (en) 1983-05-20

Family

ID=15261304

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56140117A Expired JPS5824428B2 (en) 1981-09-04 1981-09-04 Method for producing polypeptides

Country Status (1)

Country Link
JP (1) JPS5824428B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0447390Y2 (en) * 1985-01-14 1992-11-09

Also Published As

Publication number Publication date
JPS5824428B2 (en) 1983-05-20

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