GB2019411A - Peptides Related to Somatostatin - Google Patents
Peptides Related to SomatostatinInfo
- Publication number
- GB2019411A GB2019411A GB7913871A GB7913871A GB2019411A GB 2019411 A GB2019411 A GB 2019411A GB 7913871 A GB7913871 A GB 7913871A GB 7913871 A GB7913871 A GB 7913871A GB 2019411 A GB2019411 A GB 2019411A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trp
- gly
- ala
- image
- residue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Peptides of the formula: <IMAGE> wherein: x is H, -NH2, -NH-Gly-Ala, -NH-D-Ala-Ala, -NH-Gly-Gly- Gly, -NH-acetyl, or -NH-benzoyl; X1 is His or Arg; X2 is His, Glu, Tyr, Trp or Phe; X3 is Trp, D-Trp, or 6-F-D-Trp; X4 is a D- alpha -amino acid; the residue <IMAGE> has the L-configuration and the residue <IMAGE> has the L or D-configuration or the reduced, linear form thereof, or a non-toxic, pharmaceutically acceptable acid addition salt thereof which inhibit the release of growth hormone, insulin and glucagon; and show prolonged inhibition activity.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IE81279A IE48500B1 (en) | 1978-04-24 | 1979-08-08 | Peptides related to somatostatin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89943878A | 1978-04-24 | 1978-04-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
GB2019411A true GB2019411A (en) | 1979-10-31 |
GB2019411B GB2019411B (en) | 1982-06-16 |
Family
ID=25410973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7913871A Expired GB2019411B (en) | 1978-04-24 | 1979-04-20 | Peptides related to somatostatin |
Country Status (2)
Country | Link |
---|---|
BE (1) | BE875817A (en) |
GB (1) | GB2019411B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4316890A (en) * | 1979-03-16 | 1982-02-23 | Ciba-Geigy Corporation | Peptides and processes for the manufacture thereof |
-
1979
- 1979-04-20 GB GB7913871A patent/GB2019411B/en not_active Expired
- 1979-04-24 BE BE0/194806A patent/BE875817A/en not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4316890A (en) * | 1979-03-16 | 1982-02-23 | Ciba-Geigy Corporation | Peptides and processes for the manufacture thereof |
Also Published As
Publication number | Publication date |
---|---|
BE875817A (en) | 1979-10-24 |
GB2019411B (en) | 1982-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IE781151L (en) | Somatostatin analogs | |
IL102848A0 (en) | Polypeptides having growth hormone releasing activity,their use and pharmaceutical compositions containing them | |
JPS55124747A (en) | Peptide having somatostatin activity | |
ES2010299A6 (en) | Human insulin analogs and preparations containing them. | |
ES469005A1 (en) | Somatostatin analogs and intermediates thereto | |
CA2004991A1 (en) | Deletion analogues of magainin peptides | |
DE60045524D1 (en) | A chicken GnRH-II analogous to use in the reduction of tumor cell growth | |
SE7413710L (en) | ||
GB2112396B (en) | Cyclic octapeptides and pharmaceutical preparations thereof, as well as processes for their manufacture, and their use | |
ES8607990A1 (en) | Vasotocin derivatives. | |
IE782317L (en) | Biologically active peptides | |
ES8501364A1 (en) | Peptides. | |
GR3014916T3 (en) | Peptide compounds having growth hormone releasing activity. | |
MX9702275A (en) | Polypeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone. | |
GB2019411A (en) | Peptides Related to Somatostatin | |
AU1877983A (en) | Animal feed composition comprising alyl peptides | |
IE781724L (en) | Peptides | |
JPS53111096A (en) | 1-azaxanthone-3-carboxylic acid derivative and its preparation | |
JPS56108750A (en) | Polypeptide and its preparation | |
IL63022A (en) | Nonapeptide having gonadoliberine activity,its preparation and compositions containing it | |
JPS5791965A (en) | Preparation of polypeptide | |
DE3882233D1 (en) | VESSEL-ACTIVE PEPTIDES. | |
GB2021581A (en) | Stabilisation of PGl2 derivatives | |
EP0173527A3 (en) | Insulin-selective somatostatin analogs | |
JPS53132539A (en) | Protected amino acid or peptide having said protected amino acid residue |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PCNP | Patent ceased through non-payment of renewal fee |