DK1054868T3 - Substituerede pyridinoarylpiperaziner egnede til behandling af prostatahyperplasi - Google Patents

Substituerede pyridinoarylpiperaziner egnede til behandling af prostatahyperplasi

Info

Publication number
DK1054868T3
DK1054868T3 DK99934281T DK99934281T DK1054868T3 DK 1054868 T3 DK1054868 T3 DK 1054868T3 DK 99934281 T DK99934281 T DK 99934281T DK 99934281 T DK99934281 T DK 99934281T DK 1054868 T3 DK1054868 T3 DK 1054868T3
Authority
DK
Denmark
Prior art keywords
pyridinoarylpiperazines
substituted
treatment
prostate hyperplasia
hyperplasia
Prior art date
Application number
DK99934281T
Other languages
Danish (da)
English (en)
Inventor
Gee-Hong Kuo
William V Murray
Catherine P Prouty
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1054868T3 publication Critical patent/DK1054868T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK99934281T 1998-02-20 1999-02-19 Substituerede pyridinoarylpiperaziner egnede til behandling af prostatahyperplasi DK1054868T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7532198P 1998-02-20 1998-02-20
PCT/US1999/003608 WO1999042448A1 (fr) 1998-02-20 1999-02-19 Pyridino arylpiperazines substituees utiles pour le traitement de l'adenome prostatique

Publications (1)

Publication Number Publication Date
DK1054868T3 true DK1054868T3 (da) 2003-12-22

Family

ID=22124955

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99934281T DK1054868T3 (da) 1998-02-20 1999-02-19 Substituerede pyridinoarylpiperaziner egnede til behandling af prostatahyperplasi

Country Status (24)

Country Link
US (1) US6218396B1 (fr)
EP (1) EP1054868B1 (fr)
JP (1) JP2002503724A (fr)
KR (1) KR100591028B1 (fr)
CN (1) CN1121390C (fr)
AR (1) AR014626A1 (fr)
AT (1) ATE250580T1 (fr)
AU (1) AU766398B2 (fr)
BR (1) BR9909647A (fr)
CZ (1) CZ294136B6 (fr)
DE (1) DE69911582T2 (fr)
DK (1) DK1054868T3 (fr)
ES (1) ES2209468T3 (fr)
HK (1) HK1030776A1 (fr)
HU (1) HUP0100781A3 (fr)
IL (2) IL137954A0 (fr)
NO (1) NO317103B1 (fr)
NZ (1) NZ506462A (fr)
PL (1) PL342339A1 (fr)
PT (1) PT1054868E (fr)
TR (1) TR200003220T2 (fr)
TW (1) TW565555B (fr)
WO (1) WO1999042448A1 (fr)
ZA (1) ZA991315B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0984777B1 (fr) * 1997-05-12 2003-09-17 Ortho-Mcneil Pharmaceutical, Inc. Piperazines a substitution aryle utiles dans le traitement de l'adenome prostatique
CA2419036A1 (fr) 2000-08-08 2002-02-14 Ortho-Mcneil Pharmaceutical, Inc. Aryloxypiperidines non-imidazole
KR20060005009A (ko) 2001-12-28 2006-01-16 다케다 야쿠힌 고교 가부시키가이샤 배뇨 장애 예방제/치료제
EP2077262A4 (fr) * 2006-10-23 2011-12-28 Takeda Pharmaceutical Dérivé de l'iminopyridine et son utilisation
US8481569B2 (en) 2008-04-23 2013-07-09 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof
US20110039892A1 (en) * 2008-04-23 2011-02-17 Takeda Pharmaceutical Company Limited Iminopyridine derivative and use thereof
MX2010011652A (es) * 2008-04-23 2010-12-06 Takeda Pharmaceutical Derivados de iminopiridina y uso de los mismos.
CN103980195A (zh) * 2014-04-28 2014-08-13 广州医科大学 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用
CN108530391B (zh) * 2018-05-17 2022-05-17 袁牧 一种酰胺类芳基哌嗪衍生物及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2027898A6 (es) * 1991-01-24 1992-06-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina.
US5403847A (en) 1992-11-13 1995-04-04 Synaptic Pharmaceutical Corporation Use of α1C specific compounds to treat benign prostatic hyperlasia
IT1266582B1 (it) * 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
DE4425146A1 (de) * 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen
US5688795A (en) 1994-11-08 1997-11-18 Syntex (U.S.A.) Inc. 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
WO1999003833A1 (fr) * 1997-07-15 1999-01-28 Sankyo Company, Limited Derives de piperazine

Also Published As

Publication number Publication date
TR200003220T2 (tr) 2001-04-20
WO1999042448A1 (fr) 1999-08-26
ES2209468T3 (es) 2004-06-16
CZ294136B6 (cs) 2004-10-13
ATE250580T1 (de) 2003-10-15
JP2002503724A (ja) 2002-02-05
NO20004141D0 (no) 2000-08-18
CN1121390C (zh) 2003-09-17
AU3302599A (en) 1999-09-06
PL342339A1 (en) 2001-06-04
AR014626A1 (es) 2001-03-28
ZA991315B (en) 2000-11-20
KR20010041115A (ko) 2001-05-15
NO20004141L (no) 2000-10-19
HUP0100781A3 (en) 2002-12-28
EP1054868B1 (fr) 2003-09-24
BR9909647A (pt) 2000-11-21
TW565555B (en) 2003-12-11
IL137954A0 (en) 2001-10-31
CZ20003044A3 (cs) 2001-04-11
HUP0100781A2 (hu) 2001-08-28
NO317103B1 (no) 2004-08-09
KR100591028B1 (ko) 2006-06-22
IL137954A (en) 2007-06-03
DE69911582T2 (de) 2005-09-15
AU766398B2 (en) 2003-10-16
EP1054868A1 (fr) 2000-11-29
DE69911582D1 (de) 2003-10-30
PT1054868E (pt) 2004-01-30
CN1291188A (zh) 2001-04-11
HK1030776A1 (en) 2001-05-18
US6218396B1 (en) 2001-04-17
NZ506462A (en) 2003-07-25

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