DK1027365T3 - Antitumor-uridinanaloger - Google Patents

Antitumor-uridinanaloger

Info

Publication number
DK1027365T3
DK1027365T3 DK98958451T DK98958451T DK1027365T3 DK 1027365 T3 DK1027365 T3 DK 1027365T3 DK 98958451 T DK98958451 T DK 98958451T DK 98958451 T DK98958451 T DK 98958451T DK 1027365 T3 DK1027365 T3 DK 1027365T3
Authority
DK
Denmark
Prior art keywords
substituted
sugar
alkoxy
alkyl
unsubstituted
Prior art date
Application number
DK98958451T
Other languages
English (en)
Inventor
Raymond W Klecker
Lawrence Anderson
Aspandiar G Katki
Jerry M Collins
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of DK1027365T3 publication Critical patent/DK1027365T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nuclear Medicine (AREA)
DK98958451T 1997-10-30 1998-10-30 Antitumor-uridinanaloger DK1027365T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6358797P 1997-10-30 1997-10-30
PCT/US1998/023109 WO1999023104A2 (en) 1997-10-30 1998-10-30 Antitumour uridine analogues

Publications (1)

Publication Number Publication Date
DK1027365T3 true DK1027365T3 (da) 2005-05-30

Family

ID=22050193

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98958451T DK1027365T3 (da) 1997-10-30 1998-10-30 Antitumor-uridinanaloger

Country Status (9)

Country Link
EP (1) EP1027365B1 (da)
JP (2) JP2001522034A (da)
AT (1) ATE287414T1 (da)
AU (1) AU758426B2 (da)
CA (1) CA2307002C (da)
DE (1) DE69828702T2 (da)
DK (1) DK1027365T3 (da)
ES (1) ES2236962T3 (da)
WO (1) WO1999023104A2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001512830A (ja) 1997-08-08 2001-08-28 ニューバイオティックス インコーポレイテッド 生物療法耐性および化学療法耐性を克服するための方法および組成物
ES2172303T3 (es) 1998-01-23 2002-09-16 Newbiotics Inc Agentes terapeuticos obtenidos por catalisis enzimatica.
US7462605B2 (en) 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
WO2001007088A2 (en) 1999-07-22 2001-02-01 Newbiotics, Inc. Methods for treating therapy-resistant tumors
JP4982019B2 (ja) * 1999-07-22 2012-07-25 セルメド オンコロジー （ユーエスエイ）， インコーポレイテッド 酵素によって触媒される治療活性化
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
NZ547204A (en) 2000-05-26 2008-01-31 Idenix Cayman Ltd Methods and compositions for treating flaviviruses and pestiviruses
JPWO2002031492A1 (ja) * 2000-10-06 2004-02-19 株式会社生体科学研究所 異常増殖組織等を識別、定量する二次元定量画像化法
WO2002056832A2 (en) 2001-01-19 2002-07-25 Newbiotics, Inc. Methods to treat autoimmune and inflammatory conditions
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
CA2486911A1 (fr) * 2002-05-31 2003-12-11 Commissariat A L'energie Atomique Methode de criblage de banques de molecules radioactives et ses applications
HUE033832T2 (en) 2002-11-15 2018-01-29 Idenix Pharmaceuticals Llc 2'-methyl nucleosides in combination with interferon and Flaviviridae mutation
ES2586668T3 (es) 2003-05-30 2016-10-18 Gilead Pharmasset Llc Análogos de nucleósidos fluorados modificados
EP2348131A1 (en) * 2010-01-22 2011-07-27 Institut Curie Low levels of cytidine deaminase as a marker for genetic predisposition to develop cancer
JP2014062054A (ja) * 2012-09-20 2014-04-10 Gyoseiin Genshino Iinkai Kakuno Kenkyusho よう素−１２３標記チミン類似物［１２３Ｉ］−ＩａｒａＵのプローブ

Also Published As

Publication number Publication date
WO1999023104A3 (en) 2000-02-10
DE69828702D1 (de) 2005-02-24
DE69828702T2 (de) 2006-05-11
CA2307002C (en) 2008-07-29
AU1449599A (en) 1999-05-24
EP1027365A2 (en) 2000-08-16
ES2236962T3 (es) 2005-07-16
JP2001522034A (ja) 2001-11-13
EP1027365B1 (en) 2005-01-19
ATE287414T1 (de) 2005-02-15
AU758426B2 (en) 2003-03-20
JP2009108108A (ja) 2009-05-21
CA2307002A1 (en) 1999-05-14
WO1999023104A2 (en) 1999-05-14

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