ATE287414T1 - Antitumorale uridinderivate - Google Patents

Antitumorale uridinderivate

Info

Publication number
ATE287414T1
ATE287414T1 AT98958451T AT98958451T ATE287414T1 AT E287414 T1 ATE287414 T1 AT E287414T1 AT 98958451 T AT98958451 T AT 98958451T AT 98958451 T AT98958451 T AT 98958451T AT E287414 T1 ATE287414 T1 AT E287414T1
Authority
AT
Austria
Prior art keywords
substituted
sugar
alkoxy
alkyl
unsubstituted
Prior art date
Application number
AT98958451T
Other languages
English (en)
Inventor
Raymond W Klecker
Lawrence Anderson
Aspandiar G Katki
Jerry M Collins
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE287414T1 publication Critical patent/ATE287414T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nuclear Medicine (AREA)
AT98958451T 1997-10-30 1998-10-30 Antitumorale uridinderivate ATE287414T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6358797P 1997-10-30 1997-10-30
PCT/US1998/023109 WO1999023104A2 (en) 1997-10-30 1998-10-30 Antitumour uridine analogues

Publications (1)

Publication Number Publication Date
ATE287414T1 true ATE287414T1 (de) 2005-02-15

Family

ID=22050193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98958451T ATE287414T1 (de) 1997-10-30 1998-10-30 Antitumorale uridinderivate

Country Status (9)

Country Link
EP (1) EP1027365B1 (de)
JP (2) JP2001522034A (de)
AT (1) ATE287414T1 (de)
AU (1) AU758426B2 (de)
CA (1) CA2307002C (de)
DE (1) DE69828702T2 (de)
DK (1) DK1027365T3 (de)
ES (1) ES2236962T3 (de)
WO (1) WO1999023104A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE413881T1 (de) 1997-08-08 2008-11-15 Celmed Oncology Usa Inc Verfahren und zubereitungen um resistenz gegen biologische oder chemische therapien zu überwinden
EP1167972B1 (de) 1998-01-23 2017-03-08 Kiadis Pharma Intellectual Property B.V. Enzymkatalisierte therapeutische Agenzien
US7462605B2 (en) 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
AU775601B2 (en) * 1999-07-22 2004-08-05 Celmed Oncology (Usa) Inc. Enzyme catalyzed therapeutic activation
CN1391486A (zh) 1999-07-22 2003-01-15 新生物公司 治疗对治疗有抗性的肿瘤的方法
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
CA2410579C (en) 2000-05-26 2010-04-20 Jean-Pierre Sommadossi Methods and compositions for treating flaviviruses and pestiviruses
WO2002031492A1 (fr) * 2000-10-06 2002-04-18 Institute Of Whole Body Metabolism Procede d'imagerie quantifie a deux dimensions pour distinguer et quantifier une excroissance tissulaire ou similaire
CA2441350A1 (en) 2001-01-19 2002-07-25 Newbiotics, Inc. Methods to treat autoimmune and inflammatory conditions
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
JP2005534000A (ja) * 2002-05-31 2005-11-10 コミッサリア　ア　レネルジ　アトミック 放射性分子の群のスクリーニングの方法およびその使用
MXPA05005192A (es) 2002-11-15 2005-09-08 Idenix Cayman Ltd Nucleosidos ramificados en la posicion 2' y mutacion de flaviviridae.
BRPI0419345B8 (pt) 2003-05-30 2021-05-25 Gilead Pharmasset Llc uso do (2’r)-2’-desoxi-2’-flúor-2’-c-metil nucleosídeo e de uma composição farmacêutica que o compreende
EP2348131A1 (de) * 2010-01-22 2011-07-27 Institut Curie Niedrige Mengen von Cytidindeaminase als Marker für genetische Prädisposition zur Entwicklung von Krebs
JP2014062054A (ja) * 2012-09-20 2014-04-10 Gyoseiin Genshino Iinkai Kakuno Kenkyusho よう素−１２３標記チミン類似物［１２３Ｉ］−ＩａｒａＵのプローブ

Also Published As

Publication number Publication date
WO1999023104A2 (en) 1999-05-14
DK1027365T3 (da) 2005-05-30
CA2307002A1 (en) 1999-05-14
EP1027365B1 (de) 2005-01-19
JP2009108108A (ja) 2009-05-21
ES2236962T3 (es) 2005-07-16
DE69828702D1 (de) 2005-02-24
AU1449599A (en) 1999-05-24
CA2307002C (en) 2008-07-29
DE69828702T2 (de) 2006-05-11
EP1027365A2 (de) 2000-08-16
WO1999023104A3 (en) 2000-02-10
AU758426B2 (en) 2003-03-20
JP2001522034A (ja) 2001-11-13

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