DK1002080T3 - Flourescerende proteiner som celletype-specifikke meldere - Google Patents

Flourescerende proteiner som celletype-specifikke meldere

Info

Publication number
DK1002080T3
DK1002080T3 DK98940092T DK98940092T DK1002080T3 DK 1002080 T3 DK1002080 T3 DK 1002080T3 DK 98940092 T DK98940092 T DK 98940092T DK 98940092 T DK98940092 T DK 98940092T DK 1002080 T3 DK1002080 T3 DK 1002080T3
Authority
DK
Denmark
Prior art keywords
cells
cell
human mammal
cell type
fluorescent proteins
Prior art date
Application number
DK98940092T
Other languages
Danish (da)
English (en)
Inventor
Juergen Hescheler
Original Assignee
Axiogenesis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axiogenesis Ag filed Critical Axiogenesis Ag
Application granted granted Critical
Publication of DK1002080T3 publication Critical patent/DK1002080T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK98940092T 1997-07-02 1998-06-30 Flourescerende proteiner som celletype-specifikke meldere DK1002080T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19727962A DE19727962A1 (de) 1997-07-02 1997-07-02 Fluoreszierende Proteine als zelltypspezifische Reporter
PCT/EP1998/003988 WO1999001552A1 (fr) 1997-07-02 1998-06-30 Proteines fluorescentes utilisees comme rapporteurs specifiques du type cellulaire

Publications (1)

Publication Number Publication Date
DK1002080T3 true DK1002080T3 (da) 2003-05-26

Family

ID=7834239

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98940092T DK1002080T3 (da) 1997-07-02 1998-06-30 Flourescerende proteiner som celletype-specifikke meldere

Country Status (9)

Country Link
US (2) US7105344B2 (fr)
EP (1) EP1002080B9 (fr)
JP (1) JP3956154B2 (fr)
AT (1) ATE234357T1 (fr)
DE (2) DE19727962A1 (fr)
DK (1) DK1002080T3 (fr)
ES (1) ES2191324T3 (fr)
PT (1) PT1002080E (fr)
WO (1) WO1999001552A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19727962A1 (de) * 1997-07-02 1999-01-14 Juergen Hescheler Fluoreszierende Proteine als zelltypspezifische Reporter
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
CA2392051A1 (fr) * 1999-11-19 2001-05-25 Cold Spring Harbor Laboratory Souris transgeniques exprimant une proteine fluorescente
US7455983B2 (en) 2000-01-11 2008-11-25 Geron Corporation Medium for growing human embryonic stem cells
GB0014009D0 (en) * 2000-06-08 2000-08-02 Devgen Nv Compound screens relating to insulin deficiency or insulin resistance
US6576464B2 (en) 2000-11-27 2003-06-10 Geron Corporation Methods for providing differentiated stem cells
DE10136702B4 (de) * 2000-12-27 2004-04-22 Axiogenesis Ag System zur zell- und entwicklungsspezifischen Selektion differenzierender embryonaler Stammzellen, adulter Stammzellen und embryonaler Keimbahnzellen
JP4159358B2 (ja) * 2000-12-27 2008-10-01 アクシオジェネシス アーゲー 分化中の胚幹細胞、成体幹細胞および胚生殖系細胞を細胞特異的および成長特異的に選択するためのシステム
CA2441571A1 (fr) * 2001-03-20 2002-09-26 University Of Virginia Patent Foundation Procedes d'identification et de purification de cellules souches de muscle lisse
EP1551991A4 (fr) * 2002-07-26 2006-09-20 Wisconsin Alumni Res Found Cardiomyocytes fonctionnels provenant de cellules souches embryonnaires humaines
AU2004241380A1 (en) * 2003-05-20 2004-12-02 Riken Preparation of endodermal stem cells
JP4904153B2 (ja) * 2003-06-20 2012-03-28 アキシオジェネシス エージー 胚性幹（ｅｓ）細胞系での組織モデリング
CA2558946C (fr) * 2003-07-08 2013-05-21 Axiogenesis Ag Nouveau procede de preparation de corps embryoides (ebs) et utilisations correspondantes
CA2559791A1 (fr) * 2003-07-08 2005-01-20 Axiogenesis Ag Proteines secretees utilisees en tant que marqueurs de differenciation cellulaire
CA2560334A1 (fr) 2004-04-07 2005-10-20 Axiogenesis Ag Systemes de dosage tissulaire fonctionnel in vitro, non invasifs
CA2565858C (fr) 2004-05-11 2021-06-22 Axiogenesis Ag Dosage pour la decouverte de medicament reposant sur des cellules differenciees in vitro
US20060292695A1 (en) * 2005-06-22 2006-12-28 Roslin Institute Methods and kits for drug screening and toxicity testing using promoter-reporter cells derived from embryonic stem cells
US20060292694A1 (en) * 2005-06-22 2006-12-28 Roslin Institute Reporter hepatocytes and other cells for drug screening and toxicity testing
US20080152632A1 (en) * 2005-06-22 2008-06-26 Roslin Institute Promoter-reporter cells for determining drug metabolism, drug interactions, and the effects of allotype variation
EP2551343B1 (fr) * 2010-03-23 2018-05-02 Olympus Corporation Procédé pour surveiller l'état de différenciation dans une cellule souche
ITPI20100085A1 (it) 2010-07-07 2012-01-08 Sara Migliarini Procedimento per l'ingegnerizzazione genetica di cellule staminali che attivano un tracciante fluorescente vitale in seguito al differenziamento in vitro delle cellule stesse verso il tipo cellulare specifico dei neuroni serotoninergici.
JP2014176364A (ja) * 2013-03-15 2014-09-25 Olympus Corp 幹細胞の解析方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001512316A (ja) * 1997-02-13 2001-08-21 メモリアル・スローンケタリング・キャンサー・センター 細胞微環境における変化を光学的に検出する混成分子
DE19727962A1 (de) * 1997-07-02 1999-01-14 Juergen Hescheler Fluoreszierende Proteine als zelltypspezifische Reporter
JP4159358B2 (ja) * 2000-12-27 2008-10-01 アクシオジェネシス アーゲー 分化中の胚幹細胞、成体幹細胞および胚生殖系細胞を細胞特異的および成長特異的に選択するためのシステム
JP4904153B2 (ja) * 2003-06-20 2012-03-28 アキシオジェネシス エージー 胚性幹（ｅｓ）細胞系での組織モデリング
CA2558946C (fr) * 2003-07-08 2013-05-21 Axiogenesis Ag Nouveau procede de preparation de corps embryoides (ebs) et utilisations correspondantes

Also Published As

Publication number Publication date
PT1002080E (pt) 2003-06-30
DE19727962A1 (de) 1999-01-14
US7105344B2 (en) 2006-09-12
ATE234357T1 (de) 2003-03-15
JP2002508670A (ja) 2002-03-19
EP1002080B1 (fr) 2003-03-12
EP1002080A1 (fr) 2000-05-24
WO1999001552A1 (fr) 1999-01-14
ES2191324T3 (es) 2003-09-01
EP1002080B9 (fr) 2004-08-11
DE59807479D1 (de) 2003-04-17
US20060168665A1 (en) 2006-07-27
US20020092035A1 (en) 2002-07-11
JP3956154B2 (ja) 2007-08-08

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