DK0983272T3 - En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater - Google Patents

En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater

Info

Publication number
DK0983272T3
DK0983272T3 DK98916765T DK98916765T DK0983272T3 DK 0983272 T3 DK0983272 T3 DK 0983272T3 DK 98916765 T DK98916765 T DK 98916765T DK 98916765 T DK98916765 T DK 98916765T DK 0983272 T3 DK0983272 T3 DK 0983272T3
Authority
DK
Denmark
Prior art keywords
new class
compounds consisting
photoactive compounds
benzoporphyrin derivatives
benzoporphyrin
Prior art date
Application number
DK98916765T
Other languages
Danish (da)
English (en)
Inventor
Ethan Sternberg
David Dolphin
Julia G Levy
Anna M Richter
Andrew Tovey
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/918,840 external-priority patent/US5880145A/en
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of DK0983272T3 publication Critical patent/DK0983272T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK98916765T 1997-05-07 1998-04-29 En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater DK0983272T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85232697A 1997-05-07 1997-05-07
US08/918,840 US5880145A (en) 1997-05-07 1997-08-26 Class of benzoporphyrin derivative photoactive compounds
PCT/CA1998/000425 WO1998050386A1 (fr) 1997-05-07 1998-04-29 Nouvelle classe de composes photo-actifs derives de la benzoporphyrine

Publications (1)

Publication Number Publication Date
DK0983272T3 true DK0983272T3 (da) 2004-03-01

Family

ID=27127060

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98916765T DK0983272T3 (da) 1997-05-07 1998-04-29 En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater

Country Status (19)

Country Link
US (1) US5990149A (fr)
EP (1) EP0983272B1 (fr)
JP (2) JP3907212B2 (fr)
CN (1) CN1120166C (fr)
AT (1) ATE253068T1 (fr)
AU (1) AU749741B2 (fr)
CA (1) CA2288045C (fr)
CZ (1) CZ299361B6 (fr)
DE (1) DE69819318T2 (fr)
DK (1) DK0983272T3 (fr)
ES (1) ES2210740T3 (fr)
HK (1) HK1025324A1 (fr)
HU (1) HU224176B1 (fr)
IL (1) IL132494A0 (fr)
NO (1) NO314806B1 (fr)
PL (1) PL202340B1 (fr)
PT (1) PT983272E (fr)
TW (1) TW474938B (fr)
WO (1) WO1998050386A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6756396B1 (en) 1997-05-07 2004-06-29 Qlt Inc. Ethylene glycol esters as photoactive agents
KR100397131B1 (ko) * 1997-05-07 2003-09-13 유니버시티 오브 브리티시 콜롬비아 광활성제로서 모노하이드로벤조포르피린 유도체의 에틸렌글리콜 에스테르
AU4139600A (en) 1999-04-14 2000-11-14 University Of British Columbia, The 1,3-dipolar cycloadditions to polypyrrolic macrocycles
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US7122568B1 (en) 1999-11-17 2006-10-17 Qlt, Inc. Use of low-dose PDT to inhibit restenosis
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
WO2003037295A2 (fr) * 2001-11-02 2003-05-08 The Governors Of The University Of Alberta Formulations contenant un lipide-polyethylene glycol
JP2005514346A (ja) * 2001-11-09 2005-05-19 キュー エル ティー インク. 光感作剤及び皮膚浸透エンハンサーを含有する組成物並びに光力学療法におけるそれらの使用
CA2437638A1 (fr) * 2003-08-20 2005-02-20 John Robert North Therapie photodynamique
CA2457214A1 (fr) * 2004-02-06 2005-08-06 Qlt Inc. Therapie photodynamique pour le traitement de l'acne
GB0415663D0 (en) * 2004-07-13 2004-08-18 Psimei Pharmaceuticals Plc Compound
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
JP5964322B2 (ja) 2011-01-13 2016-08-03 キュー エル ティー インク.QLT Inc. 光増感剤の局所送達用医薬組成物及びその使用
MX2015000429A (es) 2012-07-11 2015-07-14 Dermira Inc Composiciones farmaceuticas para el suministro topico de fotosesibilizadores y usos de los mismos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4883790A (en) * 1987-01-20 1989-11-28 University Of British Columbia Wavelength-specific cytotoxic agents
US4920143A (en) * 1987-04-23 1990-04-24 University Of British Columbia Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US5880145A (en) * 1997-05-07 1999-03-09 The University Of British Columbia Class of benzoporphyrin derivative photoactive compounds

Also Published As

Publication number Publication date
JP2000516636A (ja) 2000-12-12
US5990149A (en) 1999-11-23
PT983272E (pt) 2004-03-31
EP0983272A1 (fr) 2000-03-08
NO995440D0 (no) 1999-11-05
AU7025798A (en) 1998-11-27
JP2004217671A (ja) 2004-08-05
ES2210740T3 (es) 2004-07-01
CA2288045A1 (fr) 1998-11-12
PL336633A1 (en) 2000-07-03
HUP0003939A3 (en) 2003-06-30
NO314806B1 (no) 2003-05-26
CA2288045C (fr) 2007-01-23
HUP0003939A2 (en) 2001-03-28
DE69819318T2 (de) 2004-08-19
IL132494A0 (en) 2001-03-19
WO1998050386A1 (fr) 1998-11-12
DE69819318D1 (de) 2003-12-04
NO995440L (no) 1999-11-05
EP0983272B1 (fr) 2003-10-29
JP3907212B2 (ja) 2007-04-18
AU749741B2 (en) 2002-07-04
PL202340B1 (pl) 2009-06-30
HK1025324A1 (en) 2000-11-10
TW474938B (en) 2002-02-01
CZ299361B6 (cs) 2008-07-02
CZ385799A3 (cs) 2000-04-12
CN1120166C (zh) 2003-09-03
ATE253068T1 (de) 2003-11-15
HU224176B1 (hu) 2005-06-28
CN1255135A (zh) 2000-05-31

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