DK0983272T3 - En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater - Google Patents
En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivaterInfo
- Publication number
- DK0983272T3 DK0983272T3 DK98916765T DK98916765T DK0983272T3 DK 0983272 T3 DK0983272 T3 DK 0983272T3 DK 98916765 T DK98916765 T DK 98916765T DK 98916765 T DK98916765 T DK 98916765T DK 0983272 T3 DK0983272 T3 DK 0983272T3
- Authority
- DK
- Denmark
- Prior art keywords
- new class
- compounds consisting
- photoactive compounds
- benzoporphyrin derivatives
- benzoporphyrin
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- MHIITNFQDPFSES-UHFFFAOYSA-N 25,26,27,28-tetrazahexacyclo[16.6.1.13,6.18,11.113,16.019,24]octacosa-1(25),2,4,6,8(27),9,11,13,15,17,19,21,23-tridecaene Chemical class N1C(C=C2C3=CC=CC=C3C(C=C3NC(=C4)C=C3)=N2)=CC=C1C=C1C=CC4=N1 MHIITNFQDPFSES-UHFFFAOYSA-N 0.000 title 1
- PLVAJLBZYYGQNL-UHFFFAOYSA-N C12CC=C(N1)C=C1C=CC(=N1)C=C1C=CC(N1)=CC=1C3=C(C(N=1)=C2)C=CC=C3 Chemical class C12CC=C(N1)C=C1C=CC(=N1)C=C1C=CC(N1)=CC=1C3=C(C(N=1)=C2)C=CC=C3 PLVAJLBZYYGQNL-UHFFFAOYSA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000002428 photodynamic therapy Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85232697A | 1997-05-07 | 1997-05-07 | |
| US08/918,840 US5880145A (en) | 1997-05-07 | 1997-08-26 | Class of benzoporphyrin derivative photoactive compounds |
| PCT/CA1998/000425 WO1998050386A1 (en) | 1997-05-07 | 1998-04-29 | A new class of benzoporphyrin derivative photoactive compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0983272T3 true DK0983272T3 (da) | 2004-03-01 |
Family
ID=27127060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98916765T DK0983272T3 (da) | 1997-05-07 | 1998-04-29 | En ny klasse af fotoaktive forbindelser, der består af benzoporphyrinderivater |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5990149A (da) |
| EP (1) | EP0983272B1 (da) |
| JP (2) | JP3907212B2 (da) |
| CN (1) | CN1120166C (da) |
| AT (1) | ATE253068T1 (da) |
| AU (1) | AU749741B2 (da) |
| CA (1) | CA2288045C (da) |
| CZ (1) | CZ299361B6 (da) |
| DE (1) | DE69819318T2 (da) |
| DK (1) | DK0983272T3 (da) |
| ES (1) | ES2210740T3 (da) |
| HU (1) | HU224176B1 (da) |
| IL (1) | IL132494A0 (da) |
| NO (1) | NO314806B1 (da) |
| PL (1) | PL202340B1 (da) |
| PT (1) | PT983272E (da) |
| TW (1) | TW474938B (da) |
| WO (1) | WO1998050386A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6756396B1 (en) | 1997-05-07 | 2004-06-29 | Qlt Inc. | Ethylene glycol esters as photoactive agents |
| AU741070B2 (en) * | 1997-05-07 | 2001-11-22 | Qlt Inc. | Ethylene glycol esters of monohydrobenzoporphyrin derivatives as photoactive agents |
| WO2000061584A1 (en) | 1999-04-14 | 2000-10-19 | The University Of British Columbia | IMPROVED β,β,-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, AND BACTERIOCHLORINS |
| US20020022032A1 (en) * | 1999-04-23 | 2002-02-21 | Curry Patrick Mark | Immuno-adjuvant PDT treatment of metastatic tumors |
| US7122568B1 (en) | 1999-11-17 | 2006-10-17 | Qlt, Inc. | Use of low-dose PDT to inhibit restenosis |
| US6984395B2 (en) * | 2001-04-11 | 2006-01-10 | Qlt, Inc. | Drug delivery system for hydrophobic drugs |
| ES2306785T3 (es) * | 2001-11-02 | 2008-11-16 | The Governors Of The University Of Alberta | Composiciones de micelas que contienen fosfolipidos pegilados y un fotosensibilizador. |
| BR0214009A (pt) * | 2001-11-09 | 2004-11-03 | Quadra Logic Tech Inc | Método e composição para estimular o crescimento de pelos sobre a pele |
| CA2437638A1 (en) * | 2003-08-20 | 2005-02-20 | John Robert North | Photodynamic therapy |
| CA2457214A1 (en) * | 2004-02-06 | 2005-08-06 | Qlt Inc. | Photodynamic therapy for the treatment of acne |
| GB0415663D0 (en) * | 2004-07-13 | 2004-08-18 | Psimei Pharmaceuticals Plc | Compound |
| FR2877943B1 (fr) * | 2004-11-16 | 2008-09-05 | Univ De Coimbra | Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique |
| CA2824768A1 (en) | 2011-01-13 | 2012-07-19 | Qlt Inc. | Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof |
| EP2872178A1 (en) | 2012-07-11 | 2015-05-20 | Dermira, Inc. | Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof |
| AU2024251073A1 (en) * | 2023-04-14 | 2025-10-23 | Nira Biosciences, Inc. | Benzoporphyrin analogs, conjugates, and methods of use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4883790A (en) * | 1987-01-20 | 1989-11-28 | University Of British Columbia | Wavelength-specific cytotoxic agents |
| US4920143A (en) * | 1987-04-23 | 1990-04-24 | University Of British Columbia | Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents |
| US5880145A (en) * | 1997-05-07 | 1999-03-09 | The University Of British Columbia | Class of benzoporphyrin derivative photoactive compounds |
-
1998
- 1998-04-29 ES ES98916765T patent/ES2210740T3/es not_active Expired - Lifetime
- 1998-04-29 EP EP98916765A patent/EP0983272B1/en not_active Expired - Lifetime
- 1998-04-29 AU AU70257/98A patent/AU749741B2/en not_active Ceased
- 1998-04-29 AT AT98916765T patent/ATE253068T1/de not_active IP Right Cessation
- 1998-04-29 CZ CZ0385799A patent/CZ299361B6/cs not_active IP Right Cessation
- 1998-04-29 WO PCT/CA1998/000425 patent/WO1998050386A1/en not_active Ceased
- 1998-04-29 IL IL13249498A patent/IL132494A0/xx active IP Right Grant
- 1998-04-29 DE DE69819318T patent/DE69819318T2/de not_active Expired - Fee Related
- 1998-04-29 PL PL336633A patent/PL202340B1/pl not_active IP Right Cessation
- 1998-04-29 HU HU0003939A patent/HU224176B1/hu not_active IP Right Cessation
- 1998-04-29 PT PT98916765T patent/PT983272E/pt unknown
- 1998-04-29 CN CN98804869A patent/CN1120166C/zh not_active Expired - Fee Related
- 1998-04-29 JP JP54757098A patent/JP3907212B2/ja not_active Expired - Fee Related
- 1998-04-29 DK DK98916765T patent/DK0983272T3/da active
- 1998-04-29 CA CA002288045A patent/CA2288045C/en not_active Expired - Fee Related
- 1998-07-21 TW TW087111990A patent/TW474938B/zh not_active IP Right Cessation
-
1999
- 1999-03-09 US US09/265,245 patent/US5990149A/en not_active Expired - Fee Related
- 1999-11-05 NO NO19995440A patent/NO314806B1/no not_active IP Right Cessation
-
2004
- 2004-03-24 JP JP2004088106A patent/JP2004217671A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT983272E (pt) | 2004-03-31 |
| CN1255135A (zh) | 2000-05-31 |
| TW474938B (en) | 2002-02-01 |
| JP3907212B2 (ja) | 2007-04-18 |
| JP2000516636A (ja) | 2000-12-12 |
| WO1998050386A1 (en) | 1998-11-12 |
| DE69819318D1 (de) | 2003-12-04 |
| NO995440L (no) | 1999-11-05 |
| CA2288045C (en) | 2007-01-23 |
| EP0983272A1 (en) | 2000-03-08 |
| CN1120166C (zh) | 2003-09-03 |
| AU7025798A (en) | 1998-11-27 |
| ES2210740T3 (es) | 2004-07-01 |
| HUP0003939A3 (en) | 2003-06-30 |
| HU224176B1 (hu) | 2005-06-28 |
| JP2004217671A (ja) | 2004-08-05 |
| IL132494A0 (en) | 2001-03-19 |
| CZ385799A3 (cs) | 2000-04-12 |
| PL202340B1 (pl) | 2009-06-30 |
| NO314806B1 (no) | 2003-05-26 |
| CZ299361B6 (cs) | 2008-07-02 |
| EP0983272B1 (en) | 2003-10-29 |
| NO995440D0 (no) | 1999-11-05 |
| HK1025324A1 (en) | 2000-11-10 |
| HUP0003939A2 (en) | 2001-03-28 |
| PL336633A1 (en) | 2000-07-03 |
| CA2288045A1 (en) | 1998-11-12 |
| AU749741B2 (en) | 2002-07-04 |
| US5990149A (en) | 1999-11-23 |
| ATE253068T1 (de) | 2003-11-15 |
| DE69819318T2 (de) | 2004-08-19 |
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