DK0975971T3 - Fremgangsmåder til påvisning af celleapoptose - Google Patents

Fremgangsmåder til påvisning af celleapoptose

Info

Publication number
DK0975971T3
DK0975971T3 DK97946547T DK97946547T DK0975971T3 DK 0975971 T3 DK0975971 T3 DK 0975971T3 DK 97946547 T DK97946547 T DK 97946547T DK 97946547 T DK97946547 T DK 97946547T DK 0975971 T3 DK0975971 T3 DK 0975971T3
Authority
DK
Denmark
Prior art keywords
methods
apoptosis
cell apoptosis
detection
detecting cell
Prior art date
Application number
DK97946547T
Other languages
Danish (da)
English (en)
Inventor
Robert Siman
Sheryl L Meyer
Donna Bozyczko-Coyne
Ratan Venkatraman Bhat
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Application granted granted Critical
Publication of DK0975971T3 publication Critical patent/DK0975971T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK97946547T 1996-11-15 1997-11-13 Fremgangsmåder til påvisning af celleapoptose DK0975971T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3096196P 1996-11-15 1996-11-15
US08/967,625 US6048703A (en) 1996-11-15 1997-11-12 Methods for detecting cell apoptosis

Publications (1)

Publication Number Publication Date
DK0975971T3 true DK0975971T3 (da) 2006-07-03

Family

ID=26706638

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97946547T DK0975971T3 (da) 1996-11-15 1997-11-13 Fremgangsmåder til påvisning af celleapoptose

Country Status (9)

Country Link
US (2) US6048703A (fr)
EP (1) EP0975971B1 (fr)
AT (1) ATE320006T1 (fr)
AU (1) AU5169998A (fr)
CA (1) CA2270866A1 (fr)
DE (1) DE69735436T2 (fr)
DK (1) DK0975971T3 (fr)
HK (1) HK1026739A1 (fr)
WO (1) WO1998021590A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342611B1 (en) * 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
ATE382148T1 (de) 1998-09-24 2008-01-15 Promega Corp Antikörper für apoptosemarker und anwendungsverfahren
EP1173486A1 (fr) * 1999-04-15 2002-01-23 Merck Frosst Canada & Co. Anticorps reconnaissant l'app clivee par les caspases et leurs procedes d'utilisation
WO2001016180A2 (fr) * 1999-08-27 2001-03-08 Board Of Regents, The University Of Texas System Compositions et utilisation de ligand cd40 et d'agoniste cd40
EP1301786B1 (fr) * 2000-07-21 2005-11-30 Evotec AG Methode de detection de l'apoptose par la determination du cytochrome c en tant que marqueur specifique de l'apoptose libere dans un milieu extracellulaire via des mecanismes de liberation cellulaire
AU2002361642A1 (en) * 2001-11-16 2003-06-10 The University Of Tennessee Research Corporation Recombinant antibody fusion proteins and methods for detection of apoptotic cells
US7357928B2 (en) 2002-04-08 2008-04-15 University Of Louisville Research Foundation, Inc. Method for the diagnosis and prognosis of malignant diseases
US7541150B2 (en) * 2002-04-08 2009-06-02 University Of Louisville Research Foundation, Inc Method for the diagnosis and prognosis of malignant diseases
CA2489520A1 (fr) * 2002-06-26 2004-01-08 University Of Louisville Research Foundation, Inc. Procede de detection de l'apoptose
US8492107B2 (en) 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
EP2207033B1 (fr) 2004-04-15 2014-06-18 University of Florida Research Foundation, Inc. Protéines neuronales en tant que biomarqueurs pour blessure traumatique du système nerveux et autres troubles neuronaux
JP4885122B2 (ja) * 2004-04-15 2012-02-29 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 癌、器官傷害、および筋肉リハビリテーション／運動過剰訓練についての診断の生物マーカーとしてのタンパク質分解マーカー
CA2590338A1 (fr) 2005-01-25 2006-08-03 Five Prime Therapeutics, Inc. Compositions et methodes de traitement de troubles cardiaques
US8379197B2 (en) * 2006-01-05 2013-02-19 Chemimage Corporation Spectroscopic systems and methods for classifying and pharmaceutically treating cells
HUE043255T2 (hu) * 2006-06-07 2019-08-28 Bioalliance Cv Antitestek, amelyek felismernek ráksejteken expresszált CD43-on és CEA-n jelenlévõ, szénhidrátot tartalmazó epitópot, és eljárások alkalmazásukra
WO2008021211A2 (fr) * 2006-08-10 2008-02-21 Fred Hutchinson Cancer Research Center Compositions et procédés de modulation de l'apoptose dans des cellules surexprimant les protéines membres de la famille bcl-2
TWI439545B (zh) 2007-12-18 2014-06-01 Bioalliance Cv 辨別癌症細胞表現之ｃｅａ與ｃｄ－４３上含醣表位的抗體與其應用方法
WO2009088837A2 (fr) * 2007-12-31 2009-07-16 The University Of Louisville Research Foundation, Inc. Procédés et produits pour cibler, capturer et caractériser des cellules souches
AU2009282117B2 (en) 2008-08-11 2016-05-12 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
WO2011041731A2 (fr) 2009-10-02 2011-04-07 Fred Hutchinson Cancer Research Center Procédé destiné à inhiber des protéines de survie apparentées aux bcl-2
WO2011041737A2 (fr) 2009-10-02 2011-04-07 Fred Hutchinson Cancer Research Center Inhibiteurs de bcl-2 à gain de fonction
WO2011062997A2 (fr) 2009-11-17 2011-05-26 Musc Foundation For Research Development Anticorps monoclonaux humains pour nucléoline humaine
PL3446714T3 (pl) 2011-06-02 2021-11-22 University Of Louisville Research Foundation, Inc. Nanocząstki sprzężone z cząsteczką skierowaną przeciwko nukleolinie
US10857237B2 (en) 2015-05-05 2020-12-08 University Of Louisville Research Foundation, Inc. Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and MRI and/or X-ray contrast agents
JP2020500508A (ja) 2016-10-28 2020-01-16 バンヤン・バイオマーカーズ・インコーポレーテッド ユビキチンｃ末端ヒドロラーゼｌ１（ｕｃｈ−ｌ１）およびグリア線維酸性タンパク質（ｇｆａｐ）に対する抗体および関連する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08511690A (ja) * 1993-06-24 1996-12-10 ザ・ジェネラル・ホスピタル・コーポレーション プログラムされた細胞死遺伝子及びタンパク質
US5536639A (en) * 1994-03-25 1996-07-16 Cephalon, Inc. Methods for detecting calpain activation by detection of calpain activated spectrin breakdown products
US5605826A (en) * 1994-06-10 1997-02-25 Panorama Research, Inc. 24 kilodalton cytoplasmic protease activating DNA fragmentation in apoptosis
US6288037B1 (en) * 1996-01-29 2001-09-11 Basf Aktiengesellschaft Substrates and inhibitors for cysteine protease ICH-1

Also Published As

Publication number Publication date
EP0975971B1 (fr) 2006-03-08
CA2270866A1 (fr) 1998-05-22
ATE320006T1 (de) 2006-03-15
DE69735436T2 (de) 2006-10-26
EP0975971A4 (fr) 2002-09-25
WO1998021590A1 (fr) 1998-05-22
HK1026739A1 (en) 2000-12-22
AU5169998A (en) 1998-06-03
DE69735436D1 (de) 2006-05-04
US7256252B1 (en) 2007-08-14
EP0975971A1 (fr) 2000-02-02
US6048703A (en) 2000-04-11

Similar Documents

Publication Publication Date Title
DK0975971T3 (da) Fremgangsmåder til påvisning af celleapoptose
CY1105446T1 (el) Διαγνωση και θepαπεια διαταραχων που συνδεονται με aur1 και aur2
DK1734368T3 (da) Annexin-autoantistoffer anvendt som markörer for lungecancer
ES2182297T3 (es) Deteccion y modulacion de lo inhibidores de las proteinas de la apoptosis (iaps) y de los polipeptidos anti-apoptoticos afines (naip) para la diagnosis y tratamiento de enfermedades proliferativas.
DE60030281D1 (de) Methoden zur verbesserung der sensitivität und spezifität von screeningverfahren für krebs und krebs-vorstufen
DK0988534T3 (da) Elektroniske fremgangsmåder og apparat til detektering af analytter
DE69938662D1 (de) Spurendetektion von analyten mit hilfe artifizieller olfaktometrie
ATE376187T1 (de) Nachweis von erkrankungen der nieren und behandlung
DK1092155T3 (da) Fremgangsmåde til tidlig diagnose af carcinomer
MX9300913A (es) Cloneo y expresion de anticuerpos monoclonales humanizados contra interleuquina-4 humana.
NO973381L (no) Diagnostisk testanordning med testområder bestående av flere sjikt, samt fremgangsmåte for bestemmelse av en analytt ved hjelp av denne
NO20003045D0 (no) Prøvedetektering for Õ initiere starten av en elektrokjemisk analyse
DE69719057D1 (de) Verfahren zur signalverstärkung
MA46814A1 (fr) Anticorps anti-lag3 radiomarqués pour imagerie immuno-pet
ATE364089T1 (de) Reagenzien und methoden zum nachweis von erkrankungen der brust
ATE454468T1 (de) Nachweis der instabilität von mikrosatelliten und verwendung davon bei der tumordiagnose
CY1105025T1 (el) Αναλυση λεπτινης βασιζομενη στην ανιχνευση εκφρασης ang-2
DE69507470D1 (de) Diagnose von krebs, dessen zellen das am tyrosin phosphorylierte crkl-protein exprimieren
EA201491411A1 (ru) Растворимый manf при поражениях бета-клеток поджелудочной железы
WO1999047925A3 (fr) Procedes et compositions pour le diagnostic de la polyarthrite rhumatoide
FI973561A (fi) Menetelmä ja yhdisteitä analysoitavien aineiden määrittämiseksi remanenssimittausten avulla ja mainittujen yhdisteiden käyttö
DE69733861D1 (de) Verwendung von neuronalem apoptose-inhibitorprotein
DE602005023329D1 (de) VERFAHREN ZUR DIAGNOSE NICHT-KLEINZELLIGER LUNGENKARZINOME ÜBER DIE tRNA-DIHYDROURIDIN-SYNTHASEAKTIVITÄT VON URLC8
FI20010868A0 (fi) Menetelmä ja välineet gluteenin indusoimien tautien havaitsemiseksi
DE60101305D1 (de) Dpi-6, ein therapeutischer biomarker in neurologischen krankheiten