DK0973918T3 - Gærceller, der omfatter mindst to kopier af et önsket gen integreret i det kromosomale genom ved mere end et ikke-ribosomalt RNA-kodende domæne, navnlig med Kluyveromyces - Google Patents
Gærceller, der omfatter mindst to kopier af et önsket gen integreret i det kromosomale genom ved mere end et ikke-ribosomalt RNA-kodende domæne, navnlig med KluyveromycesInfo
- Publication number
- DK0973918T3 DK0973918T3 DK98928202T DK98928202T DK0973918T3 DK 0973918 T3 DK0973918 T3 DK 0973918T3 DK 98928202 T DK98928202 T DK 98928202T DK 98928202 T DK98928202 T DK 98928202T DK 0973918 T3 DK0973918 T3 DK 0973918T3
- Authority
- DK
- Denmark
- Prior art keywords
- desired gene
- copies
- ribosomal rna
- gene integrated
- yeast cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97201053 | 1997-04-11 | ||
EP97201637 | 1997-06-03 | ||
PCT/EP1998/002261 WO1998046774A1 (en) | 1997-04-11 | 1998-04-14 | Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal rna encoding domain, particularly with kluyveromyces |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0973918T3 true DK0973918T3 (da) | 2008-09-22 |
Family
ID=26146351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98928202T DK0973918T3 (da) | 1997-04-11 | 1998-04-14 | Gærceller, der omfatter mindst to kopier af et önsket gen integreret i det kromosomale genom ved mere end et ikke-ribosomalt RNA-kodende domæne, navnlig med Kluyveromyces |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0973918B1 (da) |
JP (1) | JP4531868B2 (da) |
AT (1) | ATE398181T1 (da) |
AU (1) | AU8013798A (da) |
DE (1) | DE69839602D1 (da) |
DK (1) | DK0973918T3 (da) |
ES (1) | ES2308805T3 (da) |
WO (1) | WO1998046774A1 (da) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011009700A1 (en) | 2009-07-22 | 2011-01-27 | Dsm Ip Assets B.V. | Improved host cell for the production of a compound of interest |
KR20190140939A (ko) | 2017-03-29 | 2019-12-20 | 베링거 인겔하임 에르체파우 게엠베하 운트 코 카게 | 변경된 막 지질 조성물을 갖는 재조합 숙주세포 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL68733A (en) * | 1982-05-19 | 1989-01-31 | Gist Brocades Nv | Kluyveromyces cells transformed by a dna sequence encoding a polypeptide,expression vectors containing said dna sequence and process for the transformation of kluyveromyces cells by said vector |
ATE196505T1 (de) * | 1989-07-07 | 2000-10-15 | Unilever Nv | Verfahren zur herstellung eines proteins mittels eines durch mehrfachkopie-integrierung eines expressionsvektors tranformierten pilzes |
IT1251435B (it) * | 1991-09-04 | 1995-05-09 | Sclavo Spa | Vettore genetico per la integrazione multipla stabile di sequenze di dna nel genoma dei lieviti kluyveromyces lactis e saccharomyces cerevisiae e plasmidi che lo contengono. |
EP0635574B1 (en) * | 1993-07-23 | 2003-04-23 | Dsm N.V. | Selection marker gene free recombinant strains, a method for obtaining them and the use of these strains |
-
1998
- 1998-04-14 AU AU80137/98A patent/AU8013798A/en not_active Abandoned
- 1998-04-14 EP EP98928202A patent/EP0973918B1/en not_active Expired - Lifetime
- 1998-04-14 JP JP54351098A patent/JP4531868B2/ja not_active Expired - Fee Related
- 1998-04-14 DK DK98928202T patent/DK0973918T3/da active
- 1998-04-14 DE DE69839602T patent/DE69839602D1/de not_active Expired - Lifetime
- 1998-04-14 ES ES98928202T patent/ES2308805T3/es not_active Expired - Lifetime
- 1998-04-14 WO PCT/EP1998/002261 patent/WO1998046774A1/en active IP Right Grant
- 1998-04-14 AT AT98928202T patent/ATE398181T1/de active
Also Published As
Publication number | Publication date |
---|---|
AU8013798A (en) | 1998-11-11 |
JP2002514077A (ja) | 2002-05-14 |
EP0973918A1 (en) | 2000-01-26 |
DE69839602D1 (de) | 2008-07-24 |
WO1998046774A1 (en) | 1998-10-22 |
ATE398181T1 (de) | 2008-07-15 |
EP0973918B1 (en) | 2008-06-11 |
JP4531868B2 (ja) | 2010-08-25 |
ES2308805T3 (es) | 2008-12-01 |
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