DK0972519T3 - Immuntolerance-inducere - Google Patents

Immuntolerance-inducere

Info

Publication number
DK0972519T3
DK0972519T3 DK98905773T DK98905773T DK0972519T3 DK 0972519 T3 DK0972519 T3 DK 0972519T3 DK 98905773 T DK98905773 T DK 98905773T DK 98905773 T DK98905773 T DK 98905773T DK 0972519 T3 DK0972519 T3 DK 0972519T3
Authority
DK
Denmark
Prior art keywords
inducer
immunotolerance
active component
effective amount
tolerogen
Prior art date
Application number
DK98905773T
Other languages
English (en)
Inventor
Tienan Jin
Kikuya Sugiura
Haruo Morita
Susumu Ikehara
Shinji Sogo
Kazuya Yamanishi
Masakazu Adachi
Original Assignee
Jimro Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9155015A external-priority patent/JPH10306027A/ja
Priority claimed from JP9346737A external-priority patent/JPH11180892A/ja
Application filed by Jimro Co Ltd filed Critical Jimro Co Ltd
Application granted granted Critical
Publication of DK0972519T3 publication Critical patent/DK0972519T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/46434—Antigens related to induction of tolerance to non-self
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0648—Splenocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/26—Universal/off- the- shelf cellular immunotherapy; Allogenic cells or means to avoid rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Developmental Biology & Embryology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Magnetically Actuated Valves (AREA)
  • Coils Or Transformers For Communication (AREA)
  • Transmission And Conversion Of Sensor Element Output (AREA)
DK98905773T 1997-03-07 1998-03-04 Immuntolerance-inducere DK0972519T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5293097 1997-03-07
JP9155015A JPH10306027A (ja) 1997-03-07 1997-06-12 免疫寛容誘導剤
JP9346737A JPH11180892A (ja) 1997-12-16 1997-12-16 免疫寛容誘導剤

Publications (1)

Publication Number Publication Date
DK0972519T3 true DK0972519T3 (da) 2006-11-27

Family

ID=27294790

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98905773T DK0972519T3 (da) 1997-03-07 1998-03-04 Immuntolerance-inducere

Country Status (8)

Country Link
US (1) US20030091541A1 (da)
EP (1) EP0972519B1 (da)
AT (1) ATE336257T1 (da)
DE (1) DE69835591T2 (da)
DK (1) DK0972519T3 (da)
ES (1) ES2270507T3 (da)
PT (1) PT972519E (da)
WO (1) WO1998039016A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6383481B1 (en) 1998-03-30 2002-05-07 Japan Immunoresearch Laboratories Co., Ltd. Method for transplantation of hemopoietic stem cells
DE20103715U1 (de) * 2001-03-05 2002-07-25 Nawa-Heilmittel GmbH, 92361 Berngau Medizinisches Präparat zur Förderung des Anwachsens eines Transplantats, insbesondere von transplantierter Haut an einem Transplantationsort
US20050123525A1 (en) * 2003-11-13 2005-06-09 Ulrich Martin Composition and method for inducing immune tolerance towards cell, tissue and/or organ transplants
US8735618B2 (en) 2010-05-07 2014-05-27 Resource Development L.L.C. Solvent-free organosilane quaternary ammonium compositions, method of making and use
CA2782942C (en) 2012-07-12 2019-08-27 Canadian Blood Services Method for inducing immune tolerance using polymer-modified antigenic leukocytes
WO2015003240A1 (en) 2013-07-12 2015-01-15 Canadian Blood Services Acellular pro-inflammatory compositions, process for making same and methods of using same
US10561685B2 (en) 2014-07-10 2020-02-18 Canadian Bllood Services Combination therapy of acellular pro-tolerogenic and pro-inflammatory preparations for modulating the immune system
JP6429237B2 (ja) 2015-04-14 2018-11-28 国立大学法人京都大学 免疫寛容部位形成剤及び免疫抑制性細胞の誘引剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946438A (en) * 1983-09-01 1990-08-07 The Trustees Of Columbia University In The City Of New York Process for development of acceptance of transplanted organs and tissues
JPS60502103A (ja) * 1983-09-01 1985-12-05 ザ・トラステイ−ズ・オブ・コロンビア・ユニヴア−シテイ・イン・ザ・シテイ・オブ・ニユ−・ヨ−ク 移植器官及び組織の受容性を高める方法
US4861704A (en) * 1983-09-01 1989-08-29 The Trustees Of Columbia University In The City Of New York Processes for development of acceptance of transplanted organs and tissues
US5876708A (en) * 1992-02-19 1999-03-02 The General Hospital Corporation Allogeneic and xenogeneic transplantation
JPH06298654A (ja) * 1993-04-12 1994-10-25 Sumitomo Electric Ind Ltd 抗原特異的免疫抑制剤

Also Published As

Publication number Publication date
EP0972519B1 (en) 2006-08-16
US20030091541A1 (en) 2003-05-15
DE69835591T2 (de) 2007-09-13
EP0972519A1 (en) 2000-01-19
ES2270507T3 (es) 2007-04-01
DE69835591D1 (de) 2006-09-28
ATE336257T1 (de) 2006-09-15
WO1998039016A1 (fr) 1998-09-11
PT972519E (pt) 2006-12-29
EP0972519A4 (en) 2000-04-12

Similar Documents

Publication Publication Date Title
HK1061408A1 (en) Modulation of il-2-and il-15-mediated t cell responses
TR200002299T2 (tr) Epotilon kompozisyonları.
DE69739343D1 (de) Heiss-geschmolzene extrudierbare pharmazeutische formulierung
ES2186715T3 (es) Uso de un tensioactivo lipofilico en una composicion farmaceutica.
EP0783299A4 (en) COMPOUNDS AND COMPOSITIONS FOR THE ADMINISTRATION OF ACTIVE SUBSTANCES
DE69307977D1 (de) Stabilisierte Derivate von Vitamin D2 und D3 enthaltende pharmazeutische Zusammensetzungen
SE8402560D0 (sv) Farmaceutisk komposition
BR9912694A (pt) Composto para preparar medicamento de administração pulmonar
ATE240344T1 (de) Nor-pregnane zur induzierung hypothalamischer effekte
ATE202931T1 (de) Taxanderivate enthaltende arzneizubereitungen
DK0972519T3 (da) Immuntolerance-inducere
IL79816A0 (en) Pharmaceutical composition comprising a drug-polymer matrix
DE60228615D1 (de) Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung
GR3023353T3 (en) Cyclic peptide antagonists of Substance P and Substance K
KR900700124A (ko) 흑색종 치료용 il-2 및 dtic의 치료 조성물
OA07539A (fr) Nouveaux dérivés d'acides phényl aliphatiques, leur préparation, leur application comme médicaments, et les compositions les renfermant.
AR005569A1 (es) Un metodo para inducir la muerte de celulas neoplasicas mediante derivados de la piperazina
DE3866198D1 (de) Pharmazeutische zubereitung fuer die intrarektale verabreichung von calcitonin und daraus hergestellte einzeldosisformen.
DE59404784D1 (de) Neue carbonsäureester von 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren herstellung sowie deren verwendung
DE60007074D1 (de) Sulfatierte phosphatidylinositole, ihre herstellung und verwendung
EA200200234A1 (ru) Препараты для парентерального применения эстрамустин фосфата и альбумина
TW221692B (da)
FR2701952B1 (fr) Nouveaux dérivés cyclopeptidiques de l'angiopeptine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
EP0265338A3 (en) Stable therapeutical compositions based on hydrophobic vegetable oil, and process for preparing them
AU5140490A (en) Use of mixed micelles