DK0971930T3 - Fremgangsmåde til fremstilling af enkelt enantiomert narwedin - Google Patents
Fremgangsmåde til fremstilling af enkelt enantiomert narwedinInfo
- Publication number
- DK0971930T3 DK0971930T3 DK98915005T DK98915005T DK0971930T3 DK 0971930 T3 DK0971930 T3 DK 0971930T3 DK 98915005 T DK98915005 T DK 98915005T DK 98915005 T DK98915005 T DK 98915005T DK 0971930 T3 DK0971930 T3 DK 0971930T3
- Authority
- DK
- Denmark
- Prior art keywords
- narwedine
- preparation
- single enantiomeric
- solvent
- single enantiomer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9707413.2A GB9707413D0 (en) | 1997-04-11 | 1997-04-11 | Process |
PCT/GB1998/001029 WO1998046610A1 (en) | 1997-04-11 | 1998-04-08 | Process for preparing single enantiomer narwedine |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0971930T3 true DK0971930T3 (da) | 2004-01-26 |
Family
ID=10810680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98915005T DK0971930T3 (da) | 1997-04-11 | 1998-04-08 | Fremgangsmåde til fremstilling af enkelt enantiomert narwedin |
Country Status (15)
Country | Link |
---|---|
US (1) | US6392038B1 (no) |
EP (1) | EP0971930B1 (no) |
JP (1) | JP4322317B2 (no) |
KR (1) | KR100523125B1 (no) |
AT (1) | ATE253579T1 (no) |
AU (1) | AU726812B2 (no) |
CA (1) | CA2284976C (no) |
DE (1) | DE69819479T2 (no) |
DK (1) | DK0971930T3 (no) |
ES (1) | ES2209125T3 (no) |
GB (1) | GB9707413D0 (no) |
NO (1) | NO325949B1 (no) |
NZ (1) | NZ337962A (no) |
PT (1) | PT971930E (no) |
WO (1) | WO1998046610A1 (no) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7307162B2 (en) * | 2003-09-26 | 2007-12-11 | Scinopharm Taiwan, Ltd. | Resolution of a narwedine amide derivative |
EP1763337A2 (en) * | 2003-12-31 | 2007-03-21 | Actavis Group HF | Immediate, controlled and sustained release formulations of galanthamine |
WO2005065662A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Solid dosage formulations of galantamine |
WO2006018703A2 (en) * | 2004-08-16 | 2006-02-23 | Ranbaxy Laboratories Limited | Processes for preparation of narwedine and its use in the synthesis of galantamine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5428159A (en) * | 1994-04-08 | 1995-06-27 | Ciba-Geigy Corporation | Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine |
SK283877B6 (sk) * | 1994-10-21 | 2004-04-06 | Sanochemia Pharmazeutika Ag | Spôsob výroby derivátov 4a,5,9,10,11,12,-hexahydro-6H- benzofuro[3a,3,2-ef][2]benzazepínu |
-
1997
- 1997-04-11 GB GBGB9707413.2A patent/GB9707413D0/en active Pending
-
1998
- 1998-04-08 DK DK98915005T patent/DK0971930T3/da active
- 1998-04-08 DE DE69819479T patent/DE69819479T2/de not_active Expired - Lifetime
- 1998-04-08 ES ES98915005T patent/ES2209125T3/es not_active Expired - Lifetime
- 1998-04-08 JP JP54359598A patent/JP4322317B2/ja not_active Expired - Lifetime
- 1998-04-08 CA CA002284976A patent/CA2284976C/en not_active Expired - Lifetime
- 1998-04-08 PT PT98915005T patent/PT971930E/pt unknown
- 1998-04-08 KR KR10-1999-7009195A patent/KR100523125B1/ko not_active IP Right Cessation
- 1998-04-08 AU AU69296/98A patent/AU726812B2/en not_active Expired
- 1998-04-08 AT AT98915005T patent/ATE253579T1/de active
- 1998-04-08 WO PCT/GB1998/001029 patent/WO1998046610A1/en active IP Right Grant
- 1998-04-08 US US09/402,722 patent/US6392038B1/en not_active Expired - Lifetime
- 1998-04-08 EP EP98915005A patent/EP0971930B1/en not_active Expired - Lifetime
- 1998-04-08 NZ NZ337962A patent/NZ337962A/en not_active IP Right Cessation
-
1999
- 1999-10-08 NO NO19994928A patent/NO325949B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU726812B2 (en) | 2000-11-23 |
NO994928D0 (no) | 1999-10-08 |
NO325949B1 (no) | 2008-08-25 |
KR100523125B1 (ko) | 2005-10-19 |
JP2001518911A (ja) | 2001-10-16 |
NZ337962A (en) | 2001-05-25 |
EP0971930A1 (en) | 2000-01-19 |
ATE253579T1 (de) | 2003-11-15 |
DE69819479D1 (de) | 2003-12-11 |
PT971930E (pt) | 2004-02-27 |
CA2284976C (en) | 2006-10-17 |
US6392038B1 (en) | 2002-05-21 |
CA2284976A1 (en) | 1998-10-22 |
KR20010006117A (ko) | 2001-01-26 |
EP0971930B1 (en) | 2003-11-05 |
JP4322317B2 (ja) | 2009-08-26 |
GB9707413D0 (en) | 1997-05-28 |
NO994928L (no) | 1999-10-08 |
AU6929698A (en) | 1998-11-11 |
WO1998046610A1 (en) | 1998-10-22 |
DE69819479T2 (de) | 2004-08-26 |
ES2209125T3 (es) | 2004-06-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE240139T1 (de) | Co-kristallisationsprozess | |
DK1042314T3 (da) | Fremgangsmåde til fremstilling af enantiomert berigede tetrahydrobenzothiepinoxider | |
PT756594E (pt) | Preparacao de oxadiazinas artropodicidas | |
RU93004462A (ru) | Способ стереоселективного синтеза хиральных аминов | |
BR0002073A (pt) | Processo para a preparação de um composto quiral | |
DK0958281T3 (da) | Opspaltning af ritalinsyresalt | |
DK0971930T3 (da) | Fremgangsmåde til fremstilling af enkelt enantiomert narwedin | |
DK0407212T3 (da) | Enantioselektiv syntese af antifolater | |
DK0938584T3 (da) | Fremgangsmåde til fremstilling af (S)-eller (R)-3,3,3-trifluor-2-hydroxy-2-methylpropionsyre | |
ATE183995T1 (de) | Herstellung von mit enantiomer angereicherten ortho-substituierten alpha, alpha-diaromatischen methanolen | |
IT1293777B1 (it) | Processo per la preparazione di tetraazamacrocicli | |
BR9810685B1 (pt) | processo para a prepraração de um composto. | |
DK0880525T3 (da) | Fremgangsmåde til fremstilling af galanthamin | |
TW341559B (en) | Process for racemization of optically active 1-phenylethylamine derivative | |
PT1140794E (pt) | Novo processo de preparacao de aminoacidos quirais | |
DK1017666T3 (da) | Fremgangsmåde til at forøge den optiske renhed af 2R-[1-hydroxy-1-trifluormethyl-3-cyclopropylpropyn-2-yl]-4-chloranilin | |
EP0947499A3 (fr) | Procédé de préparation de la sertraline racémique | |
SE9701438D0 (sv) | A new process | |
RS49542B (sr) | Postupak dobijanja obogaćenih enantiomera N- derivata laktama | |
BR9909627A (pt) | Processo para a produção de r-(+)-6-carboxiamido-3-n-metila-mino-1,2,3,4-tetrahidr ocarbazol | |
DK0971907T3 (da) | Fremgangsmåde til fremstilling af 1,3-disubstituerede 2-nitroguanidiner | |
DK0791569T3 (da) | Fremgangsmåde til racemisering af optisk aktive aminer | |
DK0924206T3 (da) | Fremgangsmåde til fremstilling af (R)-3-hydroxy-4-butyrolacton anvendeligt til fremstilling af (R)-carnitin | |
ES2188222T3 (es) | Sintesis enantioselectiva. | |
GEP19991791B (en) | Pharmacologically Active Enantiomers and Process for its Production |