DK0958281T3 - Opspaltning af ritalinsyresalt - Google Patents
Opspaltning af ritalinsyresaltInfo
- Publication number
- DK0958281T3 DK0958281T3 DK98900603T DK98900603T DK0958281T3 DK 0958281 T3 DK0958281 T3 DK 0958281T3 DK 98900603 T DK98900603 T DK 98900603T DK 98900603 T DK98900603 T DK 98900603T DK 0958281 T3 DK0958281 T3 DK 0958281T3
- Authority
- DK
- Denmark
- Prior art keywords
- cleavage
- acid salt
- salt
- acid
- ritalic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Gyroscopes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9700912.0A GB9700912D0 (en) | 1997-01-17 | 1997-01-17 | Resolution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0958281T3 true DK0958281T3 (da) | 2004-06-14 |
Family
ID=10806137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98900603T DK0958281T3 (da) | 1997-01-17 | 1998-01-14 | Opspaltning af ritalinsyresalt |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6441178B2 (da) |
| EP (1) | EP0958281B1 (da) |
| JP (1) | JP2001508791A (da) |
| AT (1) | ATE262510T1 (da) |
| AU (1) | AU5569198A (da) |
| CA (1) | CA2272716C (da) |
| CZ (1) | CZ293045B6 (da) |
| DE (1) | DE69822606T2 (da) |
| DK (1) | DK0958281T3 (da) |
| ES (1) | ES2218799T3 (da) |
| GB (1) | GB9700912D0 (da) |
| HU (1) | HUP0000777A3 (da) |
| NO (1) | NO993517L (da) |
| PL (1) | PL189745B1 (da) |
| PT (1) | PT958281E (da) |
| WO (1) | WO1998031668A1 (da) |
| ZA (1) | ZA98374B (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5837284A (en) | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
| US5922736A (en) * | 1995-12-04 | 1999-07-13 | Celegene Corporation | Chronic, bolus administration of D-threo methylphenidate |
| US6486177B2 (en) * | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| US6962997B1 (en) | 1997-05-22 | 2005-11-08 | Celgene Corporation | Process and intermediates for resolving piperidyl acetamide steroisomers |
| US7247730B2 (en) * | 2003-03-07 | 2007-07-24 | Isp Investments Inc. | Process for the preparation of dexmethylphenidate hydrochloride |
| US20050239830A1 (en) * | 2004-04-26 | 2005-10-27 | Vikram Khetani | Methods of diminishing co-abuse potential |
| CN101076248A (zh) * | 2004-12-09 | 2007-11-21 | 塞尔基因公司 | 使用d－苏型哌甲酯的治疗 |
| US8552030B2 (en) * | 2009-05-07 | 2013-10-08 | Malladi Drugs & Pharmaceuticals Ltd. | Process for the preparation of d-threo-ritalinic acid hydrochloride by resolution of dl-threo-ritalinic acid using chiral carboxylic acid |
| EP2937336A1 (en) * | 2010-12-17 | 2015-10-28 | Rhodes Technologies | Low-temperature synthesis of methylphenidate hydrochloride |
| US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US8927010B2 (en) | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| WO2012129551A1 (en) | 2011-03-23 | 2012-09-27 | Ironshore Pharmaceuticals & Development, Inc. | Methods and compositions for treatment of attention deficit disorder |
| US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
| US10292937B2 (en) | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
| US8916588B2 (en) | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
| WO2014083572A1 (en) * | 2012-11-29 | 2014-06-05 | Zcl Chemicals Limited | A process for the preparation of d-threo-ritalinic acid salts via novel salts of intermediate thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2957880A (en) * | 1953-12-23 | 1960-10-25 | Ciba Pharm Prod Inc | Process for the conversion of stereoisomers |
| SU466229A1 (ru) * | 1973-01-23 | 1975-04-05 | Всесоюзный научно-исследовательский химико-фармацевтический институт им. С.Орджоникидзе | Способ получени гидрохлорида метилового эфира трео- -фенил- (пиперидил-2)-уксусной кислоты |
| US4285964A (en) | 1979-08-30 | 1981-08-25 | Continental Pharma | Salts of (+)-catechine, their preparation and use, and compositions containing these salts |
| US5162344A (en) | 1987-05-04 | 1992-11-10 | Robert Koch | Procaine double salt complexes |
| JP2000504008A (ja) * | 1996-02-02 | 2000-04-04 | メデバ・ユアラプ・リミテッド | Ｄ―トレオ―（ｒ，ｒ）―メチルフェニデートの調製およびエピメリゼーションによる不要エナンチオマーリサイクルの方法 |
| CA2243542C (en) * | 1996-03-08 | 2003-02-18 | Medeva Europe Limited | Resolution of threo-methylphenidate |
-
1997
- 1997-01-17 GB GBGB9700912.0A patent/GB9700912D0/en active Pending
-
1998
- 1998-01-14 CZ CZ19992302A patent/CZ293045B6/cs not_active IP Right Cessation
- 1998-01-14 EP EP98900603A patent/EP0958281B1/en not_active Expired - Lifetime
- 1998-01-14 JP JP53393298A patent/JP2001508791A/ja active Pending
- 1998-01-14 DK DK98900603T patent/DK0958281T3/da active
- 1998-01-14 PL PL98334838A patent/PL189745B1/pl not_active IP Right Cessation
- 1998-01-14 ES ES98900603T patent/ES2218799T3/es not_active Expired - Lifetime
- 1998-01-14 CA CA002272716A patent/CA2272716C/en not_active Expired - Fee Related
- 1998-01-14 DE DE69822606T patent/DE69822606T2/de not_active Expired - Fee Related
- 1998-01-14 WO PCT/GB1998/000112 patent/WO1998031668A1/en active IP Right Grant
- 1998-01-14 HU HU0000777A patent/HUP0000777A3/hu unknown
- 1998-01-14 AT AT98900603T patent/ATE262510T1/de not_active IP Right Cessation
- 1998-01-14 PT PT98900603T patent/PT958281E/pt unknown
- 1998-01-14 AU AU55691/98A patent/AU5569198A/en not_active Abandoned
- 1998-01-16 ZA ZA98374A patent/ZA98374B/xx unknown
-
1999
- 1999-07-16 NO NO993517A patent/NO993517L/no not_active Application Discontinuation
-
2000
- 2000-01-19 US US09/487,071 patent/US6441178B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CZ230299A3 (cs) | 1999-11-17 |
| ZA98374B (en) | 1999-01-22 |
| NO993517D0 (no) | 1999-07-16 |
| AU5569198A (en) | 1998-08-07 |
| WO1998031668A1 (en) | 1998-07-23 |
| PL189745B1 (pl) | 2005-09-30 |
| DE69822606T2 (de) | 2004-08-05 |
| CZ293045B6 (cs) | 2004-01-14 |
| EP0958281A1 (en) | 1999-11-24 |
| ES2218799T3 (es) | 2004-11-16 |
| EP0958281B1 (en) | 2004-03-24 |
| JP2001508791A (ja) | 2001-07-03 |
| GB9700912D0 (en) | 1997-03-05 |
| HUP0000777A3 (en) | 2000-10-30 |
| CA2272716C (en) | 2007-09-18 |
| US6441178B2 (en) | 2002-08-27 |
| ATE262510T1 (de) | 2004-04-15 |
| US20020019535A1 (en) | 2002-02-14 |
| PL334838A1 (en) | 2000-03-27 |
| NO993517L (no) | 1999-07-16 |
| DE69822606D1 (de) | 2004-04-29 |
| HUP0000777A2 (hu) | 2000-09-28 |
| PT958281E (pt) | 2004-07-30 |
| CA2272716A1 (en) | 1998-07-23 |
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