ATE216989T1 - Trennung von octahydroisochinoline enantiomeren - Google Patents

Trennung von octahydroisochinoline enantiomeren

Info

Publication number
ATE216989T1
ATE216989T1 AT98944648T AT98944648T ATE216989T1 AT E216989 T1 ATE216989 T1 AT E216989T1 AT 98944648 T AT98944648 T AT 98944648T AT 98944648 T AT98944648 T AT 98944648T AT E216989 T1 ATE216989 T1 AT E216989T1
Authority
AT
Austria
Prior art keywords
octahydroisocinoline
enantiomers
separation
racemic
octahydroisoquinoline
Prior art date
Application number
AT98944648T
Other languages
English (en)
Inventor
Iulia Demian
Kenneth D Stanley
Original Assignee
B I Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B I Chemicals Inc filed Critical B I Chemicals Inc
Application granted granted Critical
Publication of ATE216989T1 publication Critical patent/ATE216989T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98944648T 1997-09-17 1998-09-02 Trennung von octahydroisochinoline enantiomeren ATE216989T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5919397P 1997-09-17 1997-09-17
PCT/US1998/018134 WO1999014198A1 (en) 1997-09-17 1998-09-02 Separation of enantiomers of octahydroisoquinoline

Publications (1)

Publication Number Publication Date
ATE216989T1 true ATE216989T1 (de) 2002-05-15

Family

ID=22021401

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98944648T ATE216989T1 (de) 1997-09-17 1998-09-02 Trennung von octahydroisochinoline enantiomeren

Country Status (10)

Country Link
US (1) US6063925A (de)
EP (1) EP1015432B1 (de)
JP (1) JP2001516746A (de)
AT (1) ATE216989T1 (de)
CA (1) CA2303972A1 (de)
DE (1) DE69805193T2 (de)
DK (1) DK1015432T3 (de)
ES (1) ES2173615T3 (de)
PT (1) PT1015432E (de)
WO (1) WO1999014198A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518468A (ja) * 1997-09-30 2001-10-16 モレキュラー デザインズ インターナショナル，インコーポレイテッド β３アドレナリン受容体拮抗薬、拮抗薬合成物およびこれらの応用方法
US6593341B2 (en) 2001-03-29 2003-07-15 Molecular Design International, Inc. β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same
US6596734B1 (en) 2002-10-11 2003-07-22 Molecular Design International, Inc. Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3436179A1 (de) * 1984-10-03 1986-04-10 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung optisch aktiver amine
AU6518496A (en) * 1995-07-11 1997-02-10 Lonza A.G. Process for preparing optically active 1-(p-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline

Also Published As

Publication number Publication date
EP1015432A1 (de) 2000-07-05
DE69805193T2 (de) 2003-05-15
ES2173615T3 (es) 2002-10-16
DK1015432T3 (da) 2002-07-08
WO1999014198A1 (en) 1999-03-25
CA2303972A1 (en) 1999-03-25
PT1015432E (pt) 2002-09-30
JP2001516746A (ja) 2001-10-02
EP1015432B1 (de) 2002-05-02
US6063925A (en) 2000-05-16
DE69805193D1 (de) 2002-06-06

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