DK0956287T3 - 3-Aryl-2-(1-substituerede-4-piperidinyl)-1(1-di)oxo-3H-benzo[D]-isothiazol-derivater, deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktion - Google Patents

3-Aryl-2-(1-substituerede-4-piperidinyl)-1(1-di)oxo-3H-benzo[D]-isothiazol-derivater, deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktion

Info

Publication number
DK0956287T3
DK0956287T3 DK97950636T DK97950636T DK0956287T3 DK 0956287 T3 DK0956287 T3 DK 0956287T3 DK 97950636 T DK97950636 T DK 97950636T DK 97950636 T DK97950636 T DK 97950636T DK 0956287 T3 DK0956287 T3 DK 0956287T3
Authority
DK
Denmark
Prior art keywords
piperidinyl
benzo
modulators
oxo
aryl
Prior art date
Application number
DK97950636T
Other languages
Danish (da)
English (en)
Inventor
Gregory H Merriman
Barbara S Rauckman
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK0956287T3 publication Critical patent/DK0956287T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK97950636T 1996-12-23 1997-11-13 3-Aryl-2-(1-substituerede-4-piperidinyl)-1(1-di)oxo-3H-benzo[D]-isothiazol-derivater, deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktion DK0956287T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77486696A 1996-12-23 1996-12-23
PCT/US1997/021178 WO1998028295A1 (en) 1996-12-23 1997-11-13 3-aryl-2-(1-substituted-4-piperidinyl)-1(1-di)oxo-3h-benzo[d]-isothiazole derivatives, their preparation and their use as modulators of neurotransmitter function

Publications (1)

Publication Number Publication Date
DK0956287T3 true DK0956287T3 (da) 2003-11-24

Family

ID=25102528

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97950636T DK0956287T3 (da) 1996-12-23 1997-11-13 3-Aryl-2-(1-substituerede-4-piperidinyl)-1(1-di)oxo-3H-benzo[D]-isothiazol-derivater, deres fremstilling og deres anvendelse som modulatorer af neurotransmitterfunktion

Country Status (17)

Country Link
EP (1) EP0956287B1 (ko)
JP (1) JP3282827B2 (ko)
KR (1) KR20000062283A (ko)
AR (1) AR009440A1 (ko)
AT (1) ATE247111T1 (ko)
AU (1) AU716689B2 (ko)
BR (1) BR9714432A (ko)
CA (1) CA2273181C (ko)
DE (1) DE69724148T2 (ko)
DK (1) DK0956287T3 (ko)
ES (1) ES2200205T3 (ko)
HU (1) HUP9904071A3 (ko)
IL (1) IL130605A0 (ko)
NO (1) NO993085L (ko)
PT (1) PT956287E (ko)
WO (1) WO1998028295A1 (ko)
ZA (1) ZA9711337B (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1393351B1 (it) * 2009-03-16 2012-04-20 Eos Ethical Oncology Science Spa In Forma Abbreviata Eos Spa Procedimento per la preparazione della 6-(7-((1-amminociclopropil)metossi)-6-metossichinolin-4-ilossi)-n-metil-1-naftammide e suoi intermedi di sintesi

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2509797C2 (de) * 1975-03-06 1985-07-18 Dr. Karl Thomae Gmbh, 7950 Biberach Phthalimidine, deren physiologisch verträgliche Säureadditionssalze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
AT345806B (de) * 1975-03-06 1978-10-10 Thomae Gmbh Dr K Verfahren zur herstellung neuer substituierter arylalkylamine und deren salze
EP0429341A3 (en) * 1989-11-20 1991-11-13 Rhone-Poulenc Sante Heterocyclic derivatives, their preparation and pharmaceuticals containing them
FR2662696A2 (fr) * 1989-12-13 1991-12-06 Rhone Poulenc Sante Antagonistes de la serotonine, leur preparation et medicaments les contenant.
US5567718A (en) * 1994-08-11 1996-10-22 Hoechst Marion Roussel Inc. 2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors

Also Published As

Publication number Publication date
ES2200205T3 (es) 2004-03-01
AR009440A1 (es) 2000-04-12
AU716689B2 (en) 2000-03-02
DE69724148D1 (de) 2003-09-18
HUP9904071A2 (hu) 2000-05-28
ATE247111T1 (de) 2003-08-15
JP3282827B2 (ja) 2002-05-20
KR20000062283A (ko) 2000-10-25
DE69724148T2 (de) 2004-06-09
NO993085D0 (no) 1999-06-22
CA2273181A1 (en) 1998-07-02
CA2273181C (en) 2004-01-20
BR9714432A (pt) 2000-05-02
ZA9711337B (en) 1998-06-23
IL130605A0 (en) 2000-06-01
NO993085L (no) 1999-08-20
AU5358898A (en) 1998-07-17
JP2001520641A (ja) 2001-10-30
EP0956287B1 (en) 2003-08-13
HUP9904071A3 (en) 2000-07-28
WO1998028295A1 (en) 1998-07-02
EP0956287A1 (en) 1999-11-17
PT956287E (pt) 2003-11-28

Similar Documents

Publication Publication Date Title
NO20001102D0 (no) 2,3-diaryl-pyrazolo[1,5-B]pyridazinderivater, deres fremstilling og anvendelse som syklo-oksygenase 2 (COX-2) inhibitorer
DK1006110T3 (da) Derivater af acylpiperazinylpyrimidiner, fremstilling deraf og anvendelse som lægemidler
DK0810218T3 (da) 6-benzyl-2H-pyridazin-3-onderivater samt fremstilling og anvendelsen deraf som inhibitorer af prostaglandin-G/H-syntase I og II (COX I og COX II)
NO20011503L (no) Indeno-, nafto- og benzocyklohepta-dihydrotiazolderivater, deres fremstilling og anvendelse som anorektiske legemidler
NO20011956L (no) Substituerte fenylderivater, deres fremstilling og anvendelse
EE200200138A (et) Kinolüülpropüülpiperidiini derivaadid, nende valmistamine ja neid sisaldavad kompositsioonid
DK0906292T3 (da) Triazolylmercaptider og deres anvendelse som mikrobicider
DK1206457T3 (da) Biaryl-oxa(thia)zolderivater og deres anvendelse som modulatorer PPAP'ER
DK1375503T3 (da) Dioxinoderivater og deres anvendelse som dopaminagonister
DK1288206T3 (da) Substituerede benzensulfonamidderivater som prolægemidler af COX-2-inhibitorer
NO984147D0 (no) Sammensetninger som inneholder kopolymerer som tykningsmidler
DK0888297T3 (da) N-arylsulfiliminforbindelser og deres anvendelse som katalysatorer ved fremstillingen af N-arylarylsulfonamidforbindelser
DK0906417T3 (da) Formuleringer af tværbundne proteinkrystaller og deres anvendelse som katalysatorer i organiske oplösningsmidler
NO993868D0 (no) 3-piperidyl-4-oksokinazolin-derivater og medisinske preparater som inneholder slike
DK0946512T3 (da) 6-Phenylpyridyl-2-aminderivater, der er nyttige som NOS-inhibitorer
NO20005146L (no) Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter
NO962952D0 (no) 1,2,4-oksadiazolderivater og deres anvendelse som parasitticider for dyr
NO984761D0 (no) Aminoisokinoliner og aminotienopyridinderivater og deres anvendelse som antiinflammatoriske midler
NO20006460D0 (no) 4, 5, 6 og 7-Indol og indolinderivater, deres fremstilling og anvendelse
NO994510L (no) Substituerte isokinolin-derivater og deres anvendelse som antikonvulsanter
DK0879058T3 (da) Blandinger hidrørende fra frø af Eugénia Jambolana Lamarck, fremstilling af disse blandinger og visse af deres bestanddele samt anvendelse af disse som lægemidler
DK0911311T3 (da) Fremstilling af lycopenmetabolitter
NO985307L (no) Distamycinderivater, fremgangsmÕte for deres fremstilling, og deres anvende
NO995513D0 (no) N-triazolyl-2-indolkarboksamider og deres anvendelse som CCK-A agonister
DK0795547T3 (da) (Aminoalkyl- og acylaminoalkyl-oxy)benzyloxyquinoliner, fremgangsmåde til deres fremstilling og deres anvendelse som bradyk