DK0911311T3 - Fremstilling af lycopenmetabolitter - Google Patents

Fremstilling af lycopenmetabolitter

Info

Publication number
DK0911311T3
DK0911311T3 DK98119473T DK98119473T DK0911311T3 DK 0911311 T3 DK0911311 T3 DK 0911311T3 DK 98119473 T DK98119473 T DK 98119473T DK 98119473 T DK98119473 T DK 98119473T DK 0911311 T3 DK0911311 T3 DK 0911311T3
Authority
DK
Denmark
Prior art keywords
preparation
lycopene
metabolites
lycopene metabolites
Prior art date
Application number
DK98119473T
Other languages
English (en)
Inventor
Hanspeter Pfander
Bruno Traber
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0911311T3 publication Critical patent/DK0911311T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/32Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions without formation of -OH groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/02Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
    • C07C35/06Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/267Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/28Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/29Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by introduction of oxygen-containing functional groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5435Cycloaliphatic phosphonium compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98119473T 1997-10-20 1998-10-15 Fremstilling af lycopenmetabolitter DK0911311T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97118144 1997-10-20
EP98115249 1998-08-13
US09/168,143 US6008417A (en) 1997-10-20 1998-10-07 Process for making metabolites of lycopene

Publications (1)

Publication Number Publication Date
DK0911311T3 true DK0911311T3 (da) 2003-08-25

Family

ID=27238303

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98119473T DK0911311T3 (da) 1997-10-20 1998-10-15 Fremstilling af lycopenmetabolitter

Country Status (9)

Country Link
US (4) US6008417A (da)
EP (1) EP0911311B1 (da)
JP (1) JPH11189560A (da)
CN (1) CN1098243C (da)
BR (1) BR9804505A (da)
CA (1) CA2250627A1 (da)
DE (1) DE59808241D1 (da)
DK (1) DK0911311T3 (da)
ES (1) ES2197408T3 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258958B1 (en) * 1998-06-15 2001-07-10 Lonza Ag Procedure for producing formyl imidazoles
US7345091B2 (en) 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7375133B2 (en) 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US7723327B2 (en) 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US7320997B2 (en) 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
WO2004011423A2 (en) 2002-07-29 2004-02-05 Hawaii Biotech, Inc. Structural carotenoid analogs for the inhibition and amelioration of disease
US7763649B2 (en) 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US20050009788A1 (en) * 2002-07-29 2005-01-13 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling connexin 43 expression
US7401104B2 (en) * 2003-08-21 2008-07-15 Microsoft Corporation Systems and methods for synchronizing computer systems through an intermediary file system share or device
ATE526332T1 (de) * 2004-04-30 2011-10-15 Daiichi Seiyaku Co Verfahren zur herstellung von pentacyclischem taxan
US20090099061A1 (en) * 2006-01-27 2009-04-16 Foss Bente J Synthesis of carotenoid analogs or derivatives with improved antioxidant characteristics
WO2008118862A1 (en) * 2007-03-23 2008-10-02 Cardax Pharmaceuticals, Inc. Carotenoid analogs and derivatives for the prevention of platelet aggregation
CN104592076A (zh) * 2013-10-30 2015-05-06 浙江医药股份有限公司新昌制药厂 α-胡萝卜素的制备方法
US10590152B2 (en) 2017-12-14 2020-03-17 International Business Machines Corporation Pinene-based flame retardant compounds
EP3712209A1 (en) 2019-03-21 2020-09-23 SABIC Global Technologies B.V. High stiff thermoplastic compositions for thin-wall structures

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3781314A (en) * 1971-07-14 1973-12-25 Hoffmann La Roche Polyene compounds
DE2554924C3 (de) * 1975-12-06 1979-07-12 Dr. Friedrich-Karl Marcus Chemische Fabrik Kg, 2054 Geesthacht Verfahren zur Herstellung von Lycopin
US5166445A (en) * 1989-02-10 1992-11-24 Hoffman-La Roche Inc. Method for the manufacture of carotinoids and the novel intermediates

Also Published As

Publication number Publication date
ES2197408T3 (es) 2004-01-01
DE59808241D1 (de) 2003-06-12
CA2250627A1 (en) 1999-04-20
JPH11189560A (ja) 1999-07-13
US6204414B1 (en) 2001-03-20
US6271408B1 (en) 2001-08-07
EP0911311B1 (de) 2003-05-07
CN1098243C (zh) 2003-01-08
BR9804505A (pt) 2001-05-02
US6008417A (en) 1999-12-28
EP0911311A1 (de) 1999-04-28
US6040475A (en) 2000-03-21
CN1218026A (zh) 1999-06-02

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