DK0918744T3 - Racematspaltning af ketamin - Google Patents

Racematspaltning af ketamin

Info

Publication number
DK0918744T3
DK0918744T3 DK97923022T DK97923022T DK0918744T3 DK 0918744 T3 DK0918744 T3 DK 0918744T3 DK 97923022 T DK97923022 T DK 97923022T DK 97923022 T DK97923022 T DK 97923022T DK 0918744 T3 DK0918744 T3 DK 0918744T3
Authority
DK
Denmark
Prior art keywords
ketamine
pct
racemate cleavage
date nov
sec
Prior art date
Application number
DK97923022T
Other languages
Danish (da)
English (en)
Inventor
Klaus Steiner
Stefan Gangkofner
Jean-Marie Grunenwald
Original Assignee
Goedecke Gmbh
Uetikon Chemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Gmbh, Uetikon Chemie Gmbh filed Critical Goedecke Gmbh
Application granted granted Critical
Publication of DK0918744T3 publication Critical patent/DK0918744T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK97923022T 1996-05-15 1997-05-07 Racematspaltning af ketamin DK0918744T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19619665A DE19619665C2 (de) 1996-05-15 1996-05-15 Racemattrennung von Ketamin
EP97923022A EP0918744B1 (de) 1996-05-15 1997-05-07 Racemattrennung von ketamin

Publications (1)

Publication Number Publication Date
DK0918744T3 true DK0918744T3 (da) 2004-12-06

Family

ID=7794445

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97923022T DK0918744T3 (da) 1996-05-15 1997-05-07 Racematspaltning af ketamin

Country Status (20)

Country Link
US (1) US6040479A (no)
EP (1) EP0918744B1 (no)
JP (1) JP4151988B2 (no)
AT (1) ATE272606T1 (no)
AU (1) AU727528B2 (no)
CA (1) CA2253575C (no)
CZ (1) CZ293546B6 (no)
DE (2) DE19619665C2 (no)
DK (1) DK0918744T3 (no)
EE (1) EE03436B1 (no)
ES (1) ES2224247T3 (no)
HU (1) HU225773B1 (no)
IL (1) IL127026A (no)
NO (1) NO311565B1 (no)
PL (1) PL187625B1 (no)
PT (1) PT918744E (no)
SK (1) SK282699B6 (no)
TR (1) TR199802317T2 (no)
WO (1) WO1997043244A1 (no)
ZA (1) ZA974216B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0002693B8 (pt) * 2000-06-19 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis
CN111643449A (zh) 2013-03-15 2020-09-11 詹森药业有限公司 S-盐酸氯胺酮的药物组合物
HRP20211629T1 (hr) 2013-09-13 2022-02-04 National University Corporation Chiba University Primjena r-ketamina i njegove soli kao lijekova
JP6545788B2 (ja) 2014-08-13 2019-07-17 ヤンセン ファーマシューティカ エヌ．ベー． うつ病の治療方法
EP3725307A1 (en) 2014-09-15 2020-10-21 Janssen Pharmaceutica NV Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
AU2017351437B2 (en) 2016-10-27 2022-01-27 National University Corporation Chiba University Application of (S)-norketamine and salt thereof as pharmaceutical
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
US20200405663A1 (en) 2017-09-27 2020-12-31 National University Corporation Chiba University R-ketamine and derivative thereof as prophylactic or therapeutic agent for neurodegeneration disease or recognition functional disorder
SG11202005896WA (en) 2017-12-22 2020-07-29 Janssen Pharmaceuticals Inc Esketamine for the treatment of depression
EP3753557A4 (en) 2018-02-15 2021-12-01 National University Corporation Chiba University PREVENTIVE OR THERAPEUTIC AGENT AND PHARMACEUTICAL COMPOSITION FOR INFLAMMATORY DISEASES OR BONE DISEASES
JP2021523228A (ja) 2018-05-04 2021-09-02 パーセプション ニューロサイエンス，インコーポレイティド 物質乱用の治療方法
US20220110889A1 (en) 2018-12-27 2022-04-14 National University Corporation Chiba University R-ketamine and derivative thereof as prophylactic or therapeutic agent for neurodevelopmental disorder
MX2021010683A (es) 2019-03-05 2021-12-10 Janssen Pharmaceuticals Inc Esketamina para el tratamiento de la depresión.
WO2020212510A1 (en) * 2019-04-16 2020-10-22 Janssen Pharmaceutica Nv Synthetic methods of preparing esketamine
CN112125816A (zh) * 2020-03-17 2020-12-25 国药集团工业有限公司 一种氯胺酮、其衍生物或其盐的消旋化方法
CN112409195A (zh) * 2020-03-17 2021-02-26 国药集团工业有限公司 一种(s)-氯胺酮盐酸盐的制备方法及其中间体、其晶型

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH535201A (de) * 1969-12-19 1973-03-31 Bristol Myers Co Verfahren zur Spaltung von racemischen 2-(o-Chlorphenyl)-2-methylaminocyclohexanon in die optisch-aktiven Isomeren

Also Published As

Publication number Publication date
CA2253575C (en) 2005-11-29
US6040479A (en) 2000-03-21
NO985300D0 (no) 1998-11-13
CZ355898A3 (cs) 1999-04-14
HUP9903085A3 (en) 2000-05-29
DE19619665A1 (de) 1997-11-20
EE03436B1 (et) 2001-06-15
EP0918744A1 (de) 1999-06-02
HU225773B1 (en) 2007-08-28
IL127026A (en) 2004-02-19
DE19619665C2 (de) 2001-03-08
AU2894397A (en) 1997-12-05
WO1997043244A1 (de) 1997-11-20
IL127026A0 (en) 1999-09-22
SK282699B6 (sk) 2002-11-06
HUP9903085A1 (hu) 2000-04-28
ES2224247T3 (es) 2005-03-01
EE9800394A (et) 1999-06-15
AU727528B2 (en) 2000-12-14
SK152998A3 (en) 1999-07-12
CZ293546B6 (cs) 2004-06-16
DE59711834D1 (de) 2004-09-09
EP0918744B1 (de) 2004-08-04
PL187625B1 (pl) 2004-08-31
ZA974216B (en) 1997-12-10
CA2253575A1 (en) 1997-11-20
JP2000510135A (ja) 2000-08-08
JP4151988B2 (ja) 2008-09-17
NO311565B1 (no) 2001-12-10
ATE272606T1 (de) 2004-08-15
PT918744E (pt) 2004-10-29
TR199802317T2 (xx) 1999-02-22
NO985300L (no) 1998-11-13
PL329743A1 (en) 1999-04-12

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