DK0879282T3 - Immunterapi ved anvendelse af cytotoksiske T-lymfocytter (CTL) - Google Patents
Immunterapi ved anvendelse af cytotoksiske T-lymfocytter (CTL)Info
- Publication number
- DK0879282T3 DK0879282T3 DK97900365T DK97900365T DK0879282T3 DK 0879282 T3 DK0879282 T3 DK 0879282T3 DK 97900365 T DK97900365 T DK 97900365T DK 97900365 T DK97900365 T DK 97900365T DK 0879282 T3 DK0879282 T3 DK 0879282T3
- Authority
- DK
- Denmark
- Prior art keywords
- molecule
- patient
- ctl
- lymphocytes
- cytotoxic
- Prior art date
Links
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 title abstract 6
- 238000009169 immunotherapy Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 5
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 230000002159 abnormal effect Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/57—Skin; melanoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9600878.4A GB9600878D0 (en) | 1996-01-17 | 1996-01-17 | Immunotherapy |
GBGB9623471.1A GB9623471D0 (en) | 1996-11-12 | 1996-11-12 | Immunotherapy |
PCT/GB1997/000118 WO1997026328A1 (en) | 1996-01-17 | 1997-01-17 | Immunotherapy using cytotoxic t lymphocytes (ctl) |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0879282T3 true DK0879282T3 (da) | 2003-10-20 |
Family
ID=26308471
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97900365T DK0879282T3 (da) | 1996-01-17 | 1997-01-17 | Immunterapi ved anvendelse af cytotoksiske T-lymfocytter (CTL) |
Country Status (11)
Country | Link |
---|---|
US (1) | US6805861B2 (ja) |
EP (1) | EP0879282B1 (ja) |
JP (1) | JP4767371B2 (ja) |
AT (1) | ATE244300T1 (ja) |
AU (1) | AU1394497A (ja) |
CA (1) | CA2243235C (ja) |
DE (1) | DE69723230T2 (ja) |
DK (1) | DK0879282T3 (ja) |
ES (1) | ES2203782T3 (ja) |
PT (1) | PT879282E (ja) |
WO (1) | WO1997026328A1 (ja) |
Families Citing this family (107)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997026328A1 (en) | 1996-01-17 | 1997-07-24 | Imperial College Innovations Limited | Immunotherapy using cytotoxic t lymphocytes (ctl) |
US6872518B2 (en) | 1997-09-22 | 2005-03-29 | University Of Rochester | Methods for selecting polynucleotides encoding T cell epitopes |
US7030212B1 (en) | 1998-07-31 | 2006-04-18 | Haruo Sugiyama | Tumor antigen based on products of the tumor suppressor gene WT1 |
US6407063B1 (en) * | 1998-10-02 | 2002-06-18 | Ludwig Institute For Cancer Research | Tumor antigens and CTL clones isolated by a novel procedure |
EP1117679B9 (en) * | 1998-10-02 | 2010-07-07 | Ludwig Institute For Cancer Research | Tumor antigens and ctl clones isolated by a novel procedure |
GB9823897D0 (en) | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
EP1137769B1 (en) * | 1998-11-10 | 2008-09-03 | University Of Rochester | Methods for the generation of dna libraries |
AU2736400A (en) | 1999-01-27 | 2000-08-18 | University Of South Florida | Inhibition of stat3 signal transduction for human cancer therapy |
EP1118661A1 (en) * | 2000-01-13 | 2001-07-25 | Het Nederlands Kanker Instituut | T cell receptor libraries |
US20030235908A1 (en) * | 2000-02-24 | 2003-12-25 | Xcyte Therapies, Inc. | Activation and expansion of cells |
US7572631B2 (en) * | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
US6797514B2 (en) * | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
US20030119185A1 (en) * | 2000-02-24 | 2003-06-26 | Xcyte Therapies, Inc. | Activation and expansion of cells |
EP1268763A2 (en) | 2000-03-28 | 2003-01-02 | University Of Rochester | Methods of producing a library and methods of selecting polynucleotides |
AU2001259744A1 (en) * | 2000-05-11 | 2001-11-20 | Baylor Research Institute | Compositions and methods for producing antigen-presenting cells |
WO2001089539A2 (en) * | 2000-05-25 | 2001-11-29 | Xcyte Therapies, Inc. | Methods for restoring or enhancing t-cell immune surveillance following naturally or artifically induced immunosuppression |
DE10112851C1 (de) * | 2001-03-16 | 2002-10-10 | Gsf Forschungszentrum Umwelt | Semi-allogene Antitumor-Vakzine mit HLA-haplo-identischen Antigen-präsentierenden Zellen |
AU2002361559A1 (en) * | 2001-09-24 | 2003-04-28 | University Of Pittburgh Of The Commonwealth System Of Higher Education | Anticancer vaccine and diganostic methods and reagents |
US20040175373A1 (en) * | 2002-06-28 | 2004-09-09 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
US7638122B2 (en) | 2003-03-07 | 2009-12-29 | University Of South Florida | Stat3 antagonists and their use as vaccines against cancer |
AU2003300359A1 (en) * | 2003-05-08 | 2004-12-13 | Xcyte Therapies, Inc. | Generation and isolation of antigen-specific t cells |
WO2005030251A1 (en) * | 2003-09-22 | 2005-04-07 | Xcyte Therapies, Inc. | Compositions and methods to accelerate hematologic recovery |
DE10344799A1 (de) | 2003-09-26 | 2005-04-14 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
DE102004023187A1 (de) | 2004-05-11 | 2005-12-01 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
CA2580412A1 (en) * | 2004-09-13 | 2006-03-23 | Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services | Compositions comprising t cell receptors and methods of use thereof |
PL1642905T3 (pl) | 2004-10-02 | 2009-04-30 | Immatics Biotechnologies Gmbh | Epitopy immunogenicznych komórek pomocniczych T z antygenów guzów ludzkich oraz sposoby immunoterapeutyczne wykorzystujące te epitopy |
WO2007044033A2 (en) * | 2004-12-07 | 2007-04-19 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Therapeutic and diagnostic cloned mhc-unrestricted receptor specific for the muc1 tumor associated antigen |
DE102005013846A1 (de) | 2005-03-24 | 2006-10-05 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
ATE512160T1 (de) | 2005-04-26 | 2011-06-15 | Immatics Biotechnologies Gmbh | T-cell-epitope aus dem unreifen lamininrezeptorprotein (oncofoetal antigen) und deren medizinische verwendungen |
HUE038833T2 (hu) * | 2005-08-05 | 2018-11-28 | Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh | Antigénspecifikus T-sejtek létrehozása |
SI1760089T1 (sl) | 2005-09-05 | 2009-12-31 | Immatics Biotechnologies Gmbh | S tumorjem povezani peptidi, ki se veĹľejo na molekule humanega levkocitnega antigena (HLA) razreda I ali II in ustrezno cepivo proti raku |
ES2341295T3 (es) | 2005-09-05 | 2010-06-17 | Immatics Biotechnologies Gmbh | Peptidos asociados a tumores unidos promiscuamente a moleculas del antigeno de leucocito humano (hla) de clase ii. |
CA2626238C (en) | 2005-10-17 | 2015-10-06 | Sloan Kettering Institute For Cancer Research | Wt1 hla class ii-binding peptides and compositions and methods comprising same |
EP2010209B1 (en) | 2006-04-10 | 2016-06-15 | Sloan Kettering Institute For Cancer Research | Immunogenic wt-1 peptides and methods of use thereof |
US20080131415A1 (en) | 2006-11-30 | 2008-06-05 | Riddell Stanley R | Adoptive transfer of cd8 + t cell clones derived from central memory cells |
EP1932537A1 (en) * | 2006-12-12 | 2008-06-18 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Expression of transgenic T cell receptors in LAK-T cells |
ES2553270T3 (es) | 2007-07-27 | 2015-12-07 | Immatics Biotechnologies Gmbh | Nuevo epítopo inmunogénico para inmunoterapia |
CN103911358B (zh) | 2007-07-27 | 2017-03-01 | 伊玛提克斯生物技术有限公司 | 神经元和脑肿瘤的新型免疫疗法 |
RS54374B1 (en) | 2008-03-27 | 2016-04-28 | Immatics Biotechnologies Gmbh | NEW IMMUNOTHERAPY AGAINST TUMORS OF NERVOUS CELLS AND BRAIN |
RS53872B2 (sr) | 2008-05-14 | 2018-06-29 | Immatics Biotechnologies Gmbh | Novi i snažni mhc peptidi klase ii izvedeni iz survivina i neurokana |
US8748170B2 (en) | 2008-07-25 | 2014-06-10 | University of Pittsburgh—of the Commonwealth System of Higher Education | Polypeptides derived from cyclin B1 and uses thereof |
DK2172211T3 (en) | 2008-10-01 | 2015-02-16 | Immatics Biotechnologies Gmbh | Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers |
CA2743669C (en) | 2008-11-24 | 2018-10-16 | Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Fuer Gesundheit Und Umwelt (Gmbh) | High affinity t cell receptor and use thereof |
US8467973B2 (en) * | 2009-07-28 | 2013-06-18 | Promising Future, Llc | Pairing processes for preparing alloreactive cytotoxic T cells |
GB0917094D0 (en) | 2009-09-29 | 2009-11-11 | Ucl Biomedica Plc | T-cell receptor |
GB201019331D0 (en) | 2010-03-19 | 2010-12-29 | Immatics Biotechnologies Gmbh | Methods for the diagnosis and treatment of cancer based on AVL9 |
GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
WO2013106834A2 (en) | 2012-01-13 | 2013-07-18 | Memorial Sloan Kettering Cancer Center | Immunogenic wt-1 peptides and methods of use thereof |
US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
SI2945647T1 (sl) | 2013-01-15 | 2021-01-29 | Memorial Sloan Kettering Cancer Center | Imunogeni peptidi WT-1 in postopki za uporabo le-teh |
TWI777198B (zh) | 2013-08-05 | 2022-09-11 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(七) |
GB201319446D0 (en) | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
GB201408255D0 (en) | 2014-05-09 | 2014-06-25 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumours of the blood, such as acute myeloid leukemia (AML) |
GB201411037D0 (en) | 2014-06-20 | 2014-08-06 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL) |
EP3172325B1 (en) | 2014-07-22 | 2023-06-28 | The University of Notre Dame du Lac | Molecular constructs and uses thereof |
GB201501017D0 (en) | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
IL254129B2 (en) | 2015-03-27 | 2023-10-01 | Immatics Biotechnologies Gmbh | New peptides and a combination of peptides for use in immunotherapy against various tumors |
GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
GB201507030D0 (en) | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
GB201507719D0 (en) | 2015-05-06 | 2015-06-17 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers |
CN108026154B (zh) | 2015-07-01 | 2022-03-08 | 伊玛提克斯生物技术有限公司 | 用于卵巢癌和其他癌症免疫治疗的新型肽和肽组合物 |
GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
PE20180259A1 (es) | 2015-07-06 | 2018-02-05 | Immatics Biotechnologies Gmbh | Nuevos peptidos y combinacion de peptidos para usar en inmunoterapia contra el cancer esofagico y otros canceres |
GB201513921D0 (en) | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
GB201522667D0 (en) | 2015-12-22 | 2016-02-03 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers |
GB201602918D0 (en) | 2016-02-19 | 2016-04-06 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against NHL and other cancers |
MA54832A (fr) | 2016-03-01 | 2021-12-01 | Immatics Biotechnologies Gmbh | Peptides, combinaison de peptides et médicaments à base de cellules destinés à être utilisés en immunothérapie contre le cancer de la vessie et d'autres cancers |
CR20180530A (es) | 2016-04-06 | 2019-03-11 | Immatics Biotechnologies Gmbh | Nuevos peptidos y nuevas combinaciones de peptidos para el uso en la inmunoterapia contra la leucemia mieloide aguda (lma) y otros tipos de cancer |
TWI796299B (zh) | 2016-08-26 | 2023-03-21 | 德商英麥提克生物技術股份有限公司 | 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架 |
TWI796314B (zh) | 2017-01-27 | 2023-03-21 | 德商英麥提克生物技術股份有限公司 | 用於卵巢癌和其他癌症免疫治療的新型肽和肽組合物 |
SG11201909153UA (en) | 2017-04-10 | 2019-10-30 | Immatics Biotechnologies Gmbh | Peptides and combination thereof for use in the immunotherapy against cancers |
US10899819B2 (en) | 2017-04-10 | 2021-01-26 | Immatics Biotechnologies Gmbh | Peptides and combination of peptides for use in immunotherapy against leukemias and other cancers |
WO2018189148A1 (en) | 2017-04-10 | 2018-10-18 | Immatics Biotechnologies Gmbh | Peptides and combination thereof for use in the immunotherapy against cancers |
WO2019007974A1 (en) | 2017-07-07 | 2019-01-10 | Immatics Biotechnologies Gmbh | NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY OF LUNG CANCER, INCLUDING NSCLC, CPPC AND OTHER CANCERS |
BR112019028070A2 (pt) | 2017-07-07 | 2020-07-14 | Immatics Biotechnologies Gmbh | peptídeos e combinações de peptídeos para uso em imunoterapia contra câncer de pulmão, incluindo cpcnp, cppc e outros cânceres |
DE102018107224A1 (de) | 2018-02-21 | 2019-08-22 | Immatics Biotechnologies Gmbh | Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten |
TW202016131A (zh) | 2018-05-16 | 2020-05-01 | 德商英麥提克生物技術股份有限公司 | 用於抗癌免疫治療的肽 |
CN112512538A (zh) * | 2018-05-18 | 2021-03-16 | 国家儿童医疗中心 | 改进的靶向t细胞疗法 |
US20220403001A1 (en) | 2018-06-12 | 2022-12-22 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
US10925947B2 (en) | 2018-06-29 | 2021-02-23 | Immatics Biotechnologies Gmbh | A*03 restricted peptides for use in immunotherapy against cancers and related methods |
TW202019955A (zh) | 2018-07-31 | 2020-06-01 | 德商英麥提克生物技術股份有限公司 | B*07 限制肽和肽組合的抗癌免疫治療和相關方法 |
US11945850B2 (en) | 2018-09-17 | 2024-04-02 | Immatics Biotechnologies Gmbh | B*44 restricted peptides for use in immunotherapy against cancers and related methods |
TW202024121A (zh) | 2018-09-18 | 2020-07-01 | 德商英麥提克生物技術股份有限公司 | A*01 限制肽和肽組合物在抗癌免疫治療中的用途和相關方法 |
CN109294995B (zh) * | 2018-09-30 | 2020-08-04 | 北京鼎成肽源生物技术有限公司 | 一种rfft1细胞 |
CN110408657B (zh) * | 2018-09-30 | 2021-03-16 | 北京鼎成肽源生物技术有限公司 | 一种afft1细胞的构建方法 |
US20220056092A1 (en) | 2018-12-11 | 2022-02-24 | Obsidian Therapeutics, Inc. | Membrane bound il12 compositions and methods for tunable regulation |
TW202039535A (zh) | 2018-12-18 | 2020-11-01 | 德商英麥提克生物技術股份有限公司 | B*08限制肽和肽組合物抗癌免疫治療和相關方法 |
MX2021010831A (es) | 2019-03-08 | 2021-12-15 | Obsidian Therapeutics Inc | Composiciones de ligando del cumulo de diferenciación 40 (cd40l) y métodos para regulación ajustable. |
CN113966397A (zh) | 2019-03-08 | 2022-01-21 | 黑曜石疗法公司 | 人碳酸酐酶2组合物和用于可调调节的方法 |
WO2020252404A1 (en) | 2019-06-12 | 2020-12-17 | Obsidian Therapeutics, Inc. | Ca2 compositions and methods for tunable regulation |
JP2022537670A (ja) | 2019-06-12 | 2022-08-29 | オブシディアン セラピューティクス, インコーポレイテッド | Ca2の組成物および調整可能な制御方法 |
DE102019121007A1 (de) | 2019-08-02 | 2021-02-04 | Immatics Biotechnologies Gmbh | Antigenbindende Proteine, die spezifisch an MAGE-A binden |
WO2021040736A1 (en) | 2019-08-30 | 2021-03-04 | Obsidian Therapeutics, Inc. | Tandem cd19 car-based compositions and methods for immunotherapy |
MX2022002747A (es) | 2019-09-10 | 2022-04-06 | Obsidian Therapeutics Inc | Proteinas de fusion de ca2-il15 para regulacion ajustable. |
US20230056856A1 (en) | 2020-01-08 | 2023-02-23 | Obsidian Therapeutics, Inc. | Compositions and methods for tunable regulation of transcription |
EP4090365A1 (en) | 2020-01-15 | 2022-11-23 | Immatics Biotechnologies GmbH | Antigen binding proteins specifically binding prame |
WO2021262773A1 (en) | 2020-06-22 | 2021-12-30 | Obsidian Therapeutics, Inc. | Compositions and methods for tunable regulation of cas nucleases |
WO2022060806A1 (en) | 2020-09-16 | 2022-03-24 | Obsidian Therapeutics, Inc. | Compositions and methods for expression of anti-bcma chimeric antigen receptors with small molecule-regulated il15 in t cells |
TW202229312A (zh) | 2020-09-29 | 2022-08-01 | 德商英麥提克生物技術股份有限公司 | 由非hla-a*02顯露以用於不同類型癌症之免疫治療的醯胺化肽及其脫醯胺化對應物 |
DE102020125465A1 (de) | 2020-09-29 | 2022-03-31 | Immatics Biotechnologies Gmbh | Amidierte Peptide und ihre deamidierten Gegenstücke, die durch nicht-HLA-A*02-Moleküle präsentiert werden, zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten |
DE102020125457A1 (de) | 2020-09-29 | 2022-03-31 | Immatics Biotechnologies Gmbh | Amidierte Peptide und ihre deamidierten Gegenstücke, die durch HLA-A*02-Moleküle präsentiert werden, zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten |
TW202241925A (zh) | 2021-01-15 | 2022-11-01 | 德商英麥提克生物技術股份有限公司 | 用於不同類型癌症免疫治療的hla展示肽 |
WO2022184805A1 (en) | 2021-03-03 | 2022-09-09 | Immatics Biotechnologies Gmbh | Antigen binding proteins specifically binding sars-cov-2 antigenic peptides in complex with a major histocompatibility complex protein |
TW202309071A (zh) | 2021-05-05 | 2023-03-01 | 德商英麥提克生物技術股份有限公司 | 特異性結合prame之抗原結合蛋白 |
KR20240038028A (ko) | 2021-07-27 | 2024-03-22 | 이매틱스 바이오테크놀로지스 게엠베하 | Ct45에 특이적으로 결합하는 항원 결합 단백질 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61176529A (ja) | 1985-02-01 | 1986-08-08 | Shuji Sawaki | 特異的キラ−t細胞の製造方法 |
US4690915A (en) | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
US5081029A (en) * | 1985-09-25 | 1992-01-14 | Oncogen | Methods of adoptive immunotherapy for treatment of aids |
EP0257962A3 (en) | 1986-08-29 | 1989-05-24 | Becton, Dickinson and Company | Method for treatment of peripheral blood to improve lymphokine activated killer immunotherapy |
ATE107861T1 (de) * | 1986-09-19 | 1994-07-15 | Oncogen | Verwendung von aktivierten t-lymphozyten zur vorbereitung einer pharmazeutischen zusammensetzung zur behandlung von aids. |
US4844893A (en) | 1986-10-07 | 1989-07-04 | Scripps Clinic And Research Foundation | EX vivo effector cell activation for target cell killing |
JPH0279969A (ja) | 1988-09-19 | 1990-03-20 | Shigeyoshi Fujimoto | 細胞障害性t細胞誘導及び活性化の方法 |
EP0415666A1 (en) | 1989-08-29 | 1991-03-06 | Takeda Chemical Industries, Ltd. | Composition for human cell cultivation and use thereof |
AU652725B2 (en) | 1989-09-14 | 1994-09-08 | Cellco, Inc. | Method for the production of in vitro expanded lymphoid cells for use in adoptive immunotherapy |
WO1991007509A1 (en) | 1989-11-13 | 1991-05-30 | Massachusetts Institute Of Technology | Localization and characterization of the wilms's tumor gene |
US5229115A (en) | 1990-07-26 | 1993-07-20 | Immunex Corporation | Adoptive immunotherapy with interleukin-7 |
EP0553186B1 (en) | 1990-09-28 | 1999-09-01 | Immunex Corporation | Method for producing t h?-independent cytotoxic t lymphocytes |
ES2096749T3 (es) | 1990-12-14 | 1997-03-16 | Cell Genesys Inc | Cadenas quimericas para vias de transduccion de señal asociada a un receptor. |
JPH07102131B2 (ja) | 1991-07-15 | 1995-11-08 | 日本石油株式会社 | ヒトリンパ球の癌細胞に対する傷害活性を高める方法 |
KR950700402A (ko) * | 1992-01-21 | 1995-01-16 | 로이트 제이. 오울드. 에드워드 에이. 맥더모르쎄 | 세포용해성 t 세포전구체를 결정하는 방법(method for determining cytolytic t cell precursors) |
US5314813A (en) | 1992-02-19 | 1994-05-24 | Scripps Research Institute | Drosophila cell lines expressing genes encoding MHC class I antigens and B2-microglobulin and capable of assembling empty complexes and methods of making said cell lines |
US5731160A (en) * | 1992-05-26 | 1998-03-24 | Rijksuniversiteit Leiden | Induction of antigen specific T-lymphocyte responses by stimulation with peptide loaded MHC class I molecules on antigen processing defective mammalian cell lines |
CA2158281A1 (en) | 1993-03-15 | 1994-09-29 | Jay A. Berzofsky | Peptide coated dendritic cells as immunogens |
DK0751780T3 (da) * | 1993-06-21 | 2003-10-13 | Brigham & Womens Hospital | Fremgangsmåder til isolering af CD1-fremviste antigener, vacciner, som omfatter CD1-fremviste antigener, og cellelinier til anvendelse i nævnte fremgangsmåder |
WO1995004817A1 (en) | 1993-08-06 | 1995-02-16 | Cytel Corporation | Methods for ex vivo therapy using peptide-loaded antigen presenting cells for the activation of ctl |
ATE359509T1 (de) | 1994-01-06 | 2007-05-15 | Telik Inc | Ersatz für zielobjekte und verbesserten referenzplatten |
US6660276B1 (en) | 1994-02-16 | 2003-12-09 | The University Of Virginia Patent Foundation | Peptides recognized by melanoma-specific cytotoxic lymphocytes, and uses therefor |
IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
US5874560A (en) * | 1994-04-22 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Melanoma antigens and their use in diagnostic and therapeutic methods |
US5622835A (en) | 1994-04-28 | 1997-04-22 | The Wistar Institute Of Anatomy & Biology | WT1 monoclonal antibodies |
JPH10501815A (ja) * | 1994-06-07 | 1998-02-17 | リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミネソタ | 抗原特異的t細胞応答の阻害方法 |
WO1997026328A1 (en) | 1996-01-17 | 1997-07-24 | Imperial College Innovations Limited | Immunotherapy using cytotoxic t lymphocytes (ctl) |
JPH10218093A (ja) | 1997-02-05 | 1998-08-18 | Suzuki Motor Corp | 船外機 |
US7030212B1 (en) | 1998-07-31 | 2006-04-18 | Haruo Sugiyama | Tumor antigen based on products of the tumor suppressor gene WT1 |
ATE399179T1 (de) | 1998-09-30 | 2008-07-15 | Corixa Corp | Zusammensetzungen und verfahren für wt1- spezifische immunotherapie |
-
1997
- 1997-01-17 WO PCT/GB1997/000118 patent/WO1997026328A1/en active IP Right Grant
- 1997-01-17 CA CA2243235A patent/CA2243235C/en not_active Expired - Fee Related
- 1997-01-17 AT AT97900365T patent/ATE244300T1/de active
- 1997-01-17 US US09/101,413 patent/US6805861B2/en not_active Expired - Fee Related
- 1997-01-17 JP JP52578297A patent/JP4767371B2/ja not_active Expired - Fee Related
- 1997-01-17 PT PT97900365T patent/PT879282E/pt unknown
- 1997-01-17 DK DK97900365T patent/DK0879282T3/da active
- 1997-01-17 DE DE69723230T patent/DE69723230T2/de not_active Expired - Lifetime
- 1997-01-17 AU AU13944/97A patent/AU1394497A/en not_active Abandoned
- 1997-01-17 EP EP97900365A patent/EP0879282B1/en not_active Expired - Lifetime
- 1997-01-17 ES ES97900365T patent/ES2203782T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
PT879282E (pt) | 2003-11-28 |
US6805861B2 (en) | 2004-10-19 |
EP0879282A1 (en) | 1998-11-25 |
AU1394497A (en) | 1997-08-11 |
ATE244300T1 (de) | 2003-07-15 |
WO1997026328A1 (en) | 1997-07-24 |
DE69723230D1 (de) | 2003-08-07 |
CA2243235C (en) | 2010-08-10 |
CA2243235A1 (en) | 1997-07-24 |
ES2203782T3 (es) | 2004-04-16 |
DE69723230T2 (de) | 2004-05-27 |
JP2000503656A (ja) | 2000-03-28 |
US20020090362A1 (en) | 2002-07-11 |
EP0879282B1 (en) | 2003-07-02 |
JP4767371B2 (ja) | 2011-09-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0879282T3 (da) | Immunterapi ved anvendelse af cytotoksiske T-lymfocytter (CTL) | |
MD970009A (en) | Methods for inducing T cells tolerance to donor tissues or organs | |
AU8476698A (en) | Human mesenchymal stem cells from peripheral blood | |
DE69832402D1 (de) | Erzeugung von hämatopoietischen zellen aus multipotenten neuronalen stammzellen | |
BR0207775A (pt) | Lipossomos anfotéricos métodos para carregamento dos mesmos com ingredientes ativos e sua utilização | |
DK0670729T3 (da) | Anvendelse af insulin-lignende vækstfaktorer og analoger til behandling af retinale nervesygdomme | |
WO2000066730A3 (en) | Laminin 2 and methods for its use | |
TR199800912T2 (xx) | T�m�r a��s� ve a��n�n haz�rlanmas� i�in usul. | |
BR9306345A (pt) | Métodos para suprimir a habilidade de células-t de um mamífero de proliferar e para suprimir resposta imune composições para uso na supressão da capacidade de células-t de proliferarem e na supressão de resposta imune | |
DK0952772T3 (da) | Fremgangsmåder til anvendelse af mononukleare phagocytter til at fremme axonal regeneration | |
ATE210149T1 (de) | Entzündungshemmende zusammensetzung und methode, in welchen des-tyr dynorphin und analoge benutzt werden | |
EP0690125A3 (en) | Process for induction culture of cytotoxict lymphocytes having killing activity against tumor cells | |
PT941329E (pt) | Metodo para prevenir a rejeicao de enxertos em transplantacao e para produzir uma celula-hospedeiro para terapia genetica universal utilizando activacao de linfocitos (lag-3) | |
AU5323396A (en) | Methods of treating inflammation and compositions therefor | |
MX9703535A (es) | Linfocitos t dirigidos. | |
AU685540B2 (en) | T cell receptor variable transcripts as disease related markers | |
IL114343A0 (en) | Use of IGF-I in the prevention of diabetes | |
AR013853A1 (es) | Un metodo para aumentar la expresion transgenica en una poblacion de celulas de monocotiledoneas y poblacion de celulas de monocotiledoneas conexpresion transgenica aumentada. | |
IL132310A0 (en) | Cytomodulating lipophilic peptides for modulating immune system activity and inhibiting inflammation | |
MX9803610A (es) | Utilizacion de flupirtina para la profilaxis y la terapia de enfermedades que van a compañadas de un deterioro del sistema celular hermatopoyetico. | |
ATE223214T1 (de) | Von milchsäure abgeleitete butyrat-prodrugs | |
DK0883406T3 (da) | Anvendelse af IL-7 til behandling af autoimmune sygdomme og især insulinafhængig diabe-tesmellitus i særdeleshed | |
DK0863866T3 (da) | Butyrat-prodrugs afledt af mælkesyre | |
DK0789591T3 (da) | Fremgangsmåde til identifikation af individer, som lider af en celleabnormitet | |
WO1999031136A3 (en) | Methods for maintaining or restoring tissue-appropriate phenotype of soft tissue cells |