DK0866848T3 - Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme - Google Patents

Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme

Info

Publication number
DK0866848T3
DK0866848T3 DK96939719T DK96939719T DK0866848T3 DK 0866848 T3 DK0866848 T3 DK 0866848T3 DK 96939719 T DK96939719 T DK 96939719T DK 96939719 T DK96939719 T DK 96939719T DK 0866848 T3 DK0866848 T3 DK 0866848T3
Authority
DK
Denmark
Prior art keywords
methods
hosts
recombinant proteins
producing
neurospora
Prior art date
Application number
DK96939719T
Other languages
English (en)
Inventor
W Dorsey Stuart
Original Assignee
Univ Hawaii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Hawaii filed Critical Univ Hawaii
Application granted granted Critical
Publication of DK0866848T3 publication Critical patent/DK0866848T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK96939719T 1995-12-15 1996-11-12 Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme DK0866848T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/573,020 US5776730A (en) 1995-12-15 1995-12-15 Neurospora hosts for the production of recombinant proteins, and methods for producing same
PCT/US1996/018348 WO1997022687A1 (en) 1995-12-15 1996-11-12 Improved neurospora hosts for the production of recombinant proteins, and methods for producing the same

Publications (1)

Publication Number Publication Date
DK0866848T3 true DK0866848T3 (da) 2007-05-21

Family

ID=24290328

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96939719T DK0866848T3 (da) 1995-12-15 1996-11-12 Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme

Country Status (11)

Country Link
US (1) US5776730A (da)
EP (1) EP0866848B1 (da)
JP (1) JPH11510065A (da)
AT (1) ATE354636T1 (da)
AU (1) AU721592B2 (da)
CA (1) CA2240149C (da)
DE (1) DE69636922T2 (da)
DK (1) DK0866848T3 (da)
ES (1) ES2283006T3 (da)
PT (1) PT866848E (da)
WO (1) WO1997022687A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
CA2345356C (en) * 1998-10-06 2012-10-02 Mark Aaron Emalfarb Transformation system in the field of filamentous fungal hosts
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
EP1774017B1 (en) * 2004-07-26 2013-05-15 Pfenex Inc. Process for improved protein expression by strain engineering
US8680252B2 (en) 2006-12-10 2014-03-25 Dyadic International (Usa), Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) * 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
CA2736661A1 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
DE102008013689A1 (de) * 2008-03-11 2009-09-17 Tesa Se Folienanordnung
CN107868758A (zh) 2012-01-05 2018-04-03 诺华股份有限公司 蛋白酶缺陷丝状真菌细胞及其使用方法
DK2852610T3 (da) 2012-05-23 2018-09-03 Glykos Finland Oy Produktion af fucosylerede glycoproteiner
RU2016104064A (ru) 2013-07-10 2017-08-15 Новартис Аг Клетки мицелиальных грибов с множественной недостаточностью протеаз и способы их использования
EP3172333B1 (en) 2014-07-21 2020-05-13 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486533A (en) * 1982-09-02 1984-12-04 St. Louis University Filamentous fungi functional replicating extrachromosomal element
US4816405A (en) * 1984-10-24 1989-03-28 The Regents Of The University Of California Vectors for transformation by ascomycetes
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
US4935349A (en) * 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
ES2204884T3 (es) * 1988-01-05 2004-05-01 Roche Diagnostics Gmbh Procedimiento para la obtencion de proteinas o productos genicos que contienen proteinas.
CN1225550C (zh) * 1995-03-20 2005-11-02 诺沃奇梅兹有限公司 表达降低水平的金属蛋白酶的宿主细胞和在蛋白质产生中使用该宿主细胞的方法
AU7112796A (en) * 1995-09-27 1997-04-17 Chiron Corporation Method of making a protease deficient host

Also Published As

Publication number Publication date
EP0866848A1 (en) 1998-09-30
ES2283006T3 (es) 2007-10-16
AU7681196A (en) 1997-07-14
WO1997022687A1 (en) 1997-06-26
EP0866848A4 (en) 2000-03-15
EP0866848B1 (en) 2007-02-21
ATE354636T1 (de) 2007-03-15
DE69636922T2 (de) 2007-12-06
JPH11510065A (ja) 1999-09-07
CA2240149A1 (en) 1997-06-26
PT866848E (pt) 2007-03-30
CA2240149C (en) 2009-06-30
AU721592B2 (en) 2000-07-06
US5776730A (en) 1998-07-07
DE69636922D1 (de) 2007-04-05

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