DK0863213T3 - Termisk cyklus-udstyr - Google Patents

Termisk cyklus-udstyr

Info

Publication number
DK0863213T3
DK0863213T3 DK98200769T DK98200769T DK0863213T3 DK 0863213 T3 DK0863213 T3 DK 0863213T3 DK 98200769 T DK98200769 T DK 98200769T DK 98200769 T DK98200769 T DK 98200769T DK 0863213 T3 DK0863213 T3 DK 0863213T3
Authority
DK
Denmark
Prior art keywords
thermal cycle
cycle equipment
equipment
thermal
cycle
Prior art date
Application number
DK98200769T
Other languages
English (en)
Inventor
Will Bloch
Gerard J Nuovo
Original Assignee
Univ New York State Res Found
Pe Corp Ny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found, Pe Corp Ny filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of DK0863213T3 publication Critical patent/DK0863213T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK98200769T 1991-07-23 1992-07-22 Termisk cyklus-udstyr DK0863213T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73341991A 1991-07-23 1991-07-23

Publications (1)

Publication Number Publication Date
DK0863213T3 true DK0863213T3 (da) 2002-01-21

Family

ID=24947512

Family Applications (2)

Application Number Title Priority Date Filing Date
DK92306701T DK0524808T3 (da) 1991-07-23 1992-07-22 In situ-PCR-sammensætninger og anvendelse
DK98200769T DK0863213T3 (da) 1991-07-23 1992-07-22 Termisk cyklus-udstyr

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK92306701T DK0524808T3 (da) 1991-07-23 1992-07-22 In situ-PCR-sammensætninger og anvendelse

Country Status (8)

Country Link
US (1) US5538871A (da)
EP (2) EP0863213B1 (da)
JP (1) JPH0873B2 (da)
AU (1) AU645915B2 (da)
CA (2) CA2218875C (da)
DE (2) DE69232181T2 (da)
DK (2) DK0524808T3 (da)
ES (2) ES2123542T3 (da)

Families Citing this family (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
WO1994010564A1 (de) * 1992-11-05 1994-05-11 Evotec Biosystems Gmbh Verfahren zur trennung von substanzen aus verdünnten lösungen oder suspensionen
US5364790A (en) * 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
AU7640494A (en) * 1993-09-03 1995-03-22 Cellpro, Incorporated Methods for quantifying the number of cells containing a selected nucleic acid sequence in a heterogenous population of cells
US5523204A (en) * 1993-12-10 1996-06-04 Becton Dickinson And Company Detection of nucleic acids in cells by strand displacement amplification
DE4409436A1 (de) * 1994-03-19 1995-09-21 Boehringer Mannheim Gmbh Verfahren zur Bearbeitung von Nukleinsäuren
GB9507232D0 (en) * 1995-04-07 1995-05-31 Gatsby Charitable Foundation Plant pathogen resistance genes and uses thereof
JPH08196299A (ja) * 1995-01-26 1996-08-06 Tosoh Corp サーマルサイクリング反応装置及びこれに用いる反応容器
WO1996034983A1 (en) 1995-05-05 1996-11-07 The Perkin-Elmer Corporation Methods and reagents for combined pcr amplification and hybridization probing assay
CA2205057C (en) * 1995-09-12 2001-12-11 Hugh V. Cottingham Device and method for dna amplification and assay
AU7262696A (en) * 1995-10-10 1997-04-30 Regents Of The University Of California, The Detection of allele-specific mutations by allele-specific in situ reverse transcriptase polymerase chain reaction
AU1075197A (en) * 1995-11-14 1997-06-05 Mark A. Goodwin Efficient method of detecting an infectious agent in blood
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
AUPN923596A0 (en) * 1996-04-12 1996-05-09 Australian Biomedical Corporation Limited Method and apparatus for treatment of human or animal cell samples
DE19627290A1 (de) * 1996-07-06 1998-01-08 Boehringer Mannheim Gmbh Bestimmung von Analyten unter Verwendung zweier Markierungen
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
GB9624165D0 (en) * 1996-11-19 1997-01-08 Amdex A S Use of nucleic acids bound to carrier macromolecules
US6703247B1 (en) 1996-12-23 2004-03-09 American Registry Of Pathology Apparatus and methods for efficient processing of biological samples on slides
US6074868A (en) 1997-03-03 2000-06-13 Regents Of The University Of Minnesota Alumina plate method and device for controlling temperature
FR2769323B1 (fr) * 1997-10-08 2001-07-13 Suez Lyonnaise Des Eaux Moyens pour l'analyse qualitative et quantitative des populations microbiennes eventuellement presentes dans un echantillon
ATE217028T1 (de) * 1997-12-05 2002-05-15 Max Planck Gesellschaft Verfahren zur identifikation von nucleinsäuren durch matrix-assistierte laser desorptions/ionisations massenspektrometrie
WO1999043434A1 (en) * 1998-02-27 1999-09-02 Ventana Medical Systems, Inc. System and method of aspirating and dispensing reagent
US6582962B1 (en) * 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US7396508B1 (en) 2000-07-12 2008-07-08 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US7569344B2 (en) * 1998-10-26 2009-08-04 Ventana Medical Systems, Inc. Detection of human papilloma virus in papanicolaou (Pap) smears
CA2356354A1 (en) * 1998-12-23 2000-07-06 American Registry Of Pathology Apparatus and methods for efficient processing of biological samples on slides
US20060216744A1 (en) * 1998-12-23 2006-09-28 American Registry Of Pathology Armed Forces Institute Of Pathology Apparatus and methods for efficient processing of biological samples on slides
CA2365263A1 (en) * 1999-03-12 2000-09-21 Mcgill University A method for increasing the processivity of a dna- or rna-dependent polymerase and compositions therefor
DE19923584C2 (de) * 1999-05-21 2002-01-24 Memorec Medical Molecular Res Inkubationssystem
US6187567B1 (en) * 1999-09-01 2001-02-13 Akzo Nobel N.V. Methods and reagents for in situ amplification
US20060275784A1 (en) * 1999-10-26 2006-12-07 Ventana Medical Systems, Inc. Detection of Human Papilloma Virus in Papanicolaou (Pap) Smears
US6300124B1 (en) 1999-11-02 2001-10-09 Regents Of The University Of Minnesota Device and method to directly control the temperature of microscope slides
WO2001042507A1 (en) * 1999-12-09 2001-06-14 Advanced Research & Technology Institute Fluorescent in situ rt-pcr
US6448014B2 (en) * 2000-04-19 2002-09-10 Research Development Foundation PCR-hybridization assays specific for integrated retroviruses
US6864056B1 (en) * 2000-07-31 2005-03-08 The United States Of America As Represented By The Secretary Of The Army Method for detecting ribosome inactivating proteins
AU2002239679A1 (en) * 2000-12-20 2002-07-01 The Regents Of The University Of California Rolling circle amplification detection of rna and dna
ES2169701B1 (es) * 2000-12-21 2003-11-01 Univ Jaen Reactor microcristalografico.
CA2348042A1 (en) 2001-06-04 2002-12-04 Ann Huletsky Sequences for detection and identification of methicillin-resistant staphylococcus aureus
US7553619B2 (en) 2002-02-08 2009-06-30 Qiagen Gmbh Detection method using dissociated rolling circle amplification
US6818420B2 (en) 2002-02-27 2004-11-16 Biosource International, Inc. Methods of using FET labeled oligonucleotides that include a 3′-5′ exonuclease resistant quencher domain and compositions for practicing the same
US6977162B2 (en) * 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
US7208274B2 (en) * 2002-03-01 2007-04-24 Ravgen, Inc. Rapid analysis of variations in a genome
US7727720B2 (en) * 2002-05-08 2010-06-01 Ravgen, Inc. Methods for detection of genetic disorders
US20070178478A1 (en) * 2002-05-08 2007-08-02 Dhallan Ravinder S Methods for detection of genetic disorders
US7442506B2 (en) * 2002-05-08 2008-10-28 Ravgen, Inc. Methods for detection of genetic disorders
WO2004022770A2 (en) * 2002-09-05 2004-03-18 Invitrogen Corporation Compositions and methods for synthesizing nucleic acids
US20040121338A1 (en) * 2002-12-19 2004-06-24 Alsmadi Osama A. Real-time detection of rolling circle amplification products
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US7955795B2 (en) * 2003-06-06 2011-06-07 Qiagen Gmbh Method of whole genome amplification with reduced artifact production
CA2457607A1 (en) * 2003-02-12 2004-08-12 Agroterra Biotech Inc. Method of mutagenic chain reaction
US8043834B2 (en) 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
US20040248103A1 (en) * 2003-06-04 2004-12-09 Feaver William John Proximity-mediated rolling circle amplification
US20050032464A1 (en) * 2003-08-07 2005-02-10 Swisher Robert G. Polishing pad having edge surface treatment
JP2005110621A (ja) * 2003-10-10 2005-04-28 Aisin Seiki Co Ltd 核酸増幅方法及び核酸増幅用試薬キット
WO2005038044A1 (ja) * 2003-10-20 2005-04-28 Sysmex Corporation 細胞処理方法
US7759057B2 (en) * 2004-02-04 2010-07-20 Ut-Battelle, Llc Method for analyzing microbial communities
WO2005080989A1 (en) * 2004-02-13 2005-09-01 Molecular Probes, Inc. Biotin recognition sensors and high-throughput assays
GB0406015D0 (en) * 2004-03-17 2004-04-21 Dynal Biotech Asa Improvements in magnetic polymer particles
US7700281B2 (en) * 2004-06-30 2010-04-20 Usb Corporation Hot start nucleic acid amplification
US20060161076A1 (en) * 2005-01-06 2006-07-20 Diamics, Inc. Systems and methods for collection of cell clusters
US20060189893A1 (en) * 2005-01-06 2006-08-24 Diamics, Inc. Systems and methods for detecting abnormal cells
US8309303B2 (en) 2005-04-01 2012-11-13 Qiagen Gmbh Reverse transcription and amplification of RNA with simultaneous degradation of DNA
US20060263811A1 (en) * 2005-05-03 2006-11-23 Geunsook Jeon Materials and kits for use in hot-start PCR, and methods of amplifying nucleic acids in a polymerase chain reaction
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
US11834720B2 (en) 2005-10-11 2023-12-05 Geneohm Sciences, Inc. Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx
RU2394915C2 (ru) * 2006-03-24 2010-07-20 Александр Борисович Четверин Бесконтактные способы обнаружения молекулярных колоний, наборы реагентов и устройство для их осуществления
BRPI0709282B8 (pt) 2006-03-29 2021-05-25 Merial Ltd vacina contra estreptococos
AU2007261552A1 (en) * 2006-06-19 2007-12-27 Becton, Dickinson And Company Methods and compositions for obtaining amplifiable nucleic acids from tissues, cells, or viruses exposed to transport media
WO2008038507A1 (fr) * 2006-09-26 2008-04-03 Olympus Corporation Substrat et procédé de réaction d'un liquide réactif
CN105349685B (zh) 2007-04-06 2020-08-04 贝克顿·迪金森公司 用于鉴定碳青霉烯酶基因的组合物和方法
EP3708682B1 (en) * 2008-02-01 2022-11-23 The General Hospital Corporation Use of microvesicles in diagnosis and prognosis of medical diseases and conditions
WO2009124012A1 (en) * 2008-03-31 2009-10-08 Dow Global Technologies Inc. A design for rapidly cloning one or more polypeptide chains into an expression system
IT1397110B1 (it) * 2008-12-29 2012-12-28 St Microelectronics Rousset Microreattore autosigillante e metodo per eseguire una reazione
CN102388150A (zh) 2009-02-19 2012-03-21 吉恩奥姆科技公司 用于检测和鉴定超广谱β-内酰胺酶的方法
CN102498397B (zh) 2009-07-16 2016-04-06 总医院有限公司 核酸分析
JP5916610B2 (ja) 2009-09-03 2016-05-11 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 直接的な化学的溶解のための方法および組成物
EP3865590B1 (en) 2009-09-09 2024-04-10 The General Hospital Corporation Use of microvesicles in analyzing kras mutations
EP2475988B1 (en) 2009-09-09 2018-11-14 The General Hospital Corporation Use of microvesicles in analyzing nucleic acid profiles
US8383793B2 (en) 2010-04-15 2013-02-26 St. Jude Children's Research Hospital Methods and compositions for the diagnosis and treatment of cancer resistant to anaplastic lymphoma kinase (ALK) kinase inhibitors
US20140045915A1 (en) 2010-08-31 2014-02-13 The General Hospital Corporation Cancer-related biological materials in microvesicles
WO2012032519A2 (en) 2010-09-07 2012-03-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of diagnosing parkinson's disease
EP2638057B1 (en) 2010-11-10 2019-03-06 Exosome Diagnostics, Inc. Method for isolation of nucleic acid containing particles and extraction of nucleic acids therefrom
AU2011253984A1 (en) 2010-12-07 2012-06-28 Biobalance Llc Method For Identifying E. Coli M-17
US20130316358A1 (en) 2011-01-31 2013-11-28 Yeda Research And Development Co. Ltd. Methods of diagnosing disease using overlap extension pcr
EP2481812A1 (en) 2011-01-31 2012-08-01 Westfälische Wilhelms-Universität Münster Molecular sexing of avian subjects
WO2012142233A1 (en) 2011-04-14 2012-10-18 St. Jude Children's Research Hospital Methods and compositions for detecting and modulating a novel mtor complex
US20140212871A1 (en) 2011-05-11 2014-07-31 Exosome Diagnostics, Inc. Nucleic Acid Extraction from Heterogeneous Biological Materials
EP3492606B1 (en) 2011-08-22 2023-10-04 Exosome Diagnostics, Inc. Urine biomarkers
WO2013071239A1 (en) 2011-11-10 2013-05-16 Exosome Diagnostics, Inc. Cerebrospinal fluid assay
PT2809810T (pt) 2012-01-06 2020-02-14 Viomics Inc Sistema e método de detetar rnas alterados por cancro do pulmão no sangue periférico
SG11201405196VA (en) * 2012-02-27 2014-09-26 Ecole Polytech Sample processing device with detachable slide
CN108424972B (zh) 2012-04-06 2021-11-05 基因欧姆科技加拿大公司 用于检测和鉴定MREJ型xxi的耐甲氧西林金黄色葡萄球菌(MRSA)的序列
US9695416B2 (en) 2012-07-18 2017-07-04 Siemens Healthcare Diagnostics Inc. Method of normalizing biological samples
CA2883220C (en) 2012-08-30 2022-09-20 Exosome Diagnostics, Inc. Controls for nucleic acid assays
US20150252428A1 (en) 2012-10-03 2015-09-10 Exosome Diagnostics, Inc. Use of microvesicles in diagnosis, prognosis, and treatment of medical diseases and conditions
WO2014108850A2 (en) 2013-01-09 2014-07-17 Yeda Research And Development Co. Ltd. High throughput transcriptome analysis
RU2668164C2 (ru) 2013-08-06 2018-09-26 Эксосам Дайэгностикс, Инк. Когорты биомаркеров мочи, профиль экспрессии генов и способы их применения
EP3125907A4 (en) 2014-04-01 2017-11-29 Cornell University Use of double-stranded dna in exosomes: a novel biomarker in cancer detection
EP4306659A3 (en) 2014-04-14 2024-03-27 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. A method and kit for determining the tissue or cell origin of dna
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
CN104789568B (zh) * 2015-03-20 2017-11-21 中国科学院南海海洋研究所 一种用于检测石斑鱼虹彩病毒感染的dna核酸适配体及其筛选方法和应用
CN104789569B (zh) * 2015-03-20 2017-11-21 中国科学院南海海洋研究所 一种用于检测石斑鱼虹彩病毒感染的dna核酸适配体及其筛选方法和应用
EP3368686A1 (en) 2015-10-30 2018-09-05 Exact Sciences Development Company, LLC Multiplex amplification detection assay and isolation and detection of dna from plasma
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
IL294121B2 (en) 2016-03-03 2023-09-01 Memed Diagnostics Ltd An RNA test to diagnose the type of infection
CN109563547A (zh) 2016-04-15 2019-04-02 外来体诊断公司 间变性淋巴瘤激酶(alk)核酸和alk融合转录物的基于血浆的检测及其在癌症诊断和治疗中的用途
AU2017263886B2 (en) 2016-05-13 2023-11-09 Exosome Diagnostics, Inc. Automated and manual methods for isolation of extracellular vesicles and co-isolation of cell-free DNA from biofluids
EP3491381A1 (en) 2016-07-29 2019-06-05 Streck, Inc. Suspension composition for hematology analysis control
US11396676B2 (en) 2016-10-21 2022-07-26 Exosome Diagnostics, Inc. Sequencing and analysis of exosome associated nucleic acids
AU2017366813B2 (en) 2016-11-30 2023-04-20 Exosome Diagnostics, Inc. Methods and compositions to detect mutations in plasma using exosomal RNA and cell free DNA from non-small cell lung cancer patients
EP3562959A2 (en) 2017-01-02 2019-11-06 Exosome Diagnostics, Inc. Methods to distinguish rna and dna in a combined preparation
CN111133106A (zh) 2017-07-12 2020-05-08 外来体诊断公司 用于分离和富集生物流体来源的细胞外囊泡的方法及其使用方法
US11345957B2 (en) 2017-07-18 2022-05-31 Exosome Diagnostics, Inc. Methods of treating glioblastoma in a subject informed by exosomal RNA signatures
WO2019183055A1 (en) 2018-03-19 2019-09-26 Modernatx, Inc. Assembly and error reduction of synthetic genes from oligonucleotides
US20210230701A1 (en) 2018-06-06 2021-07-29 Exosome Diagnostics, Inc. Methods for developing urine biomarkers and for detecting bladder cancer
WO2020036926A1 (en) 2018-08-17 2020-02-20 Cellecta, Inc. Multiplex preparation of barcoded gene specific dna fragments
WO2020060994A1 (en) 2018-09-17 2020-03-26 The University Of North Carolina At Chapel Hill Method for quantifying dna fragments in a sample by size
WO2020106853A1 (en) 2018-11-20 2020-05-28 Exosome Diagnostics, Inc. Compositions and methods for internal controls of microvesicle isolations
EP4055189A1 (en) 2019-11-04 2022-09-14 Mirnax Biosens, S.L. Bivalent reverse primer
EP3901286A1 (en) 2020-04-24 2021-10-27 Mirnax Biosens, S.L. Bivalent reverse primer
CN115552037A (zh) 2020-03-16 2022-12-30 北卡罗来纳大学教堂山分校 用于选择性检测肿瘤源性病毒dna的组合物和方法
EP4133113A1 (en) 2020-04-06 2023-02-15 Fast Track Diagnostics Luxembourg S.a.r.l. Pcr based diagnostic kit, compositions and methods for amplification and detection of sars-cov-2
IL278473A (en) 2020-11-03 2022-06-01 Yeda Res & Dev Methods for diagnosing and determining treatment in multiple myeloma
FR3130844A1 (fr) 2021-12-22 2023-06-23 Bforcure Composition et procédé d’amplification de séquences d’acides nucléiques
WO2024038457A1 (en) 2022-08-18 2024-02-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A method for determining the tissue or cell of origin of dna

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) * 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
CA1339653C (en) * 1986-02-25 1998-02-03 Larry J. Johnson Appartus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
US5021335A (en) * 1988-06-17 1991-06-04 The Board Of Trustees Of The Leland Stanford Junior University In situ transcription in cells and tissues
US5188963A (en) * 1989-11-17 1993-02-23 Gene Tec Corporation Device for processing biological specimens for analysis of nucleic acids
US5281516A (en) * 1988-08-02 1994-01-25 Gene Tec Corporation Temperature control apparatus and method
WO1991006679A1 (en) * 1989-10-24 1991-05-16 Stratagene An improved method for hybridizing nucleic acids using single-stranded nucleic acid binding protein
US5346672A (en) * 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
US5273881A (en) * 1990-05-07 1993-12-28 Daikin Industries, Ltd. Diagnostic applications of double D-loop formation
US5230997A (en) * 1990-07-19 1993-07-27 The United States Of America As Represented By The Department Of Health And Human Services Methods of detecting the presence of human herpesvirus-7 infection
GB9123463D0 (en) * 1991-11-05 1991-12-18 Hybaid Ltd Reaction temperature control device

Also Published As

Publication number Publication date
DE69227076D1 (de) 1998-10-29
ES2165653T3 (es) 2002-03-16
EP0863213A1 (en) 1998-09-09
US5538871A (en) 1996-07-23
DE69232181T2 (de) 2002-06-20
JPH05336971A (ja) 1993-12-21
DK0524808T3 (da) 1999-06-14
DE69232181D1 (de) 2001-12-06
CA2074214C (en) 2000-02-22
CA2218875A1 (en) 1993-01-24
JPH0873B2 (ja) 1996-01-10
CA2074214A1 (en) 1993-01-24
EP0863213B1 (en) 2001-10-31
EP0524808B1 (en) 1998-09-23
AU645915B2 (en) 1994-01-27
AU2041992A (en) 1993-02-25
ES2123542T3 (es) 1999-01-16
EP0524808A3 (en) 1993-07-14
CA2218875C (en) 2000-11-07
EP0524808A2 (en) 1993-01-27
DE69227076T2 (de) 1999-06-02

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