DK0856581T3 - Stabilt transficerede cellelinjer, der udtrykker GABA-A-receptorer - Google Patents

Stabilt transficerede cellelinjer, der udtrykker GABA-A-receptorer

Info

Publication number
DK0856581T3
DK0856581T3 DK97203995T DK97203995T DK0856581T3 DK 0856581 T3 DK0856581 T3 DK 0856581T3 DK 97203995 T DK97203995 T DK 97203995T DK 97203995 T DK97203995 T DK 97203995T DK 0856581 T3 DK0856581 T3 DK 0856581T3
Authority
DK
Denmark
Prior art keywords
sub
receptors
cell lines
stably transfected
transfected cell
Prior art date
Application number
DK97203995T
Other languages
Danish (da)
English (en)
Inventor
Karen L Hadingham
Paul J Whiting
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929225776A external-priority patent/GB9225776D0/en
Priority claimed from GB939318528A external-priority patent/GB9318528D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of DK0856581T3 publication Critical patent/DK0856581T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK97203995T 1992-12-10 1993-12-07 Stabilt transficerede cellelinjer, der udtrykker GABA-A-receptorer DK0856581T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929225776A GB9225776D0 (en) 1992-12-10 1992-12-10 Cell line
GB939318528A GB9318528D0 (en) 1993-09-07 1993-09-07 Cell line
EP94902039A EP0673419B1 (de) 1992-12-10 1993-12-07 Stabil transfizierte zelllinien welche gaba-a rezeptoren exprimieren

Publications (1)

Publication Number Publication Date
DK0856581T3 true DK0856581T3 (da) 2006-03-27

Family

ID=26302133

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97203995T DK0856581T3 (da) 1992-12-10 1993-12-07 Stabilt transficerede cellelinjer, der udtrykker GABA-A-receptorer

Country Status (9)

Country Link
US (1) US5652100A (de)
EP (3) EP0856581B1 (de)
JP (1) JP3464672B2 (de)
AT (2) ATE170921T1 (de)
AU (1) AU680852B2 (de)
DE (3) DE69333923T2 (de)
DK (1) DK0856581T3 (de)
ES (2) ES2296064T3 (de)
WO (1) WO1994013799A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9420010D0 (en) * 1994-10-01 1994-11-16 Marck Sharp & Dohme Limited Nucleic acids
GB9503601D0 (en) 1995-02-23 1995-04-12 Merck Sharp & Dohme Method of treatment and method of manufacture of medicament
WO1997017369A2 (en) * 1995-11-09 1997-05-15 Trustees Of Boston University Dna comprising a neuron-specific transcriptional promoter and its use in a gene therapy vector
EP0934528B1 (de) * 1996-10-25 2002-09-04 Neurosearch A/S Methode zur identifizierung von verbindungen mit anxiolytischem potential
JP2001505423A (ja) * 1996-11-25 2001-04-24 メルク シヤープ エンド ドーム リミテツド 新規クローン化ＧＡＢＡ受容体サブユニットｃＤＮＡ配列および安定にコトランスフェクトされた細胞系
GB9708479D0 (en) 1997-04-25 1997-06-18 Merck Sharp & Dohme Nucleic acids
US7029870B1 (en) 1997-07-03 2006-04-18 Human Genome Sciences, Inc. Gabaa receptor epsilon subunits
GB9715164D0 (en) * 1997-07-19 1997-09-24 Medical Res Council Improvements in or relating to expression of nucleic acid sequences in cerebellar cells
US6762294B2 (en) 1999-02-19 2004-07-13 The United States Of America As Represented By The Department Of Health And Human Services Polynucleotides encoding polymorphic human GABAA receptor α-6 subunit
DE60024231T2 (de) * 1999-02-19 2006-08-03 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Polymorphismus im gen für die menschliche gaba a rezeptor alpha 6 untereinheit
CA2425124A1 (en) * 2000-10-05 2002-04-11 Hanns Mohler Selective anxiolytic therapeutic agents
US7282344B2 (en) * 2001-06-06 2007-10-16 Neurosearch A/S Cation conducting GABAA receptors and their use
CA2625210A1 (en) * 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
NZ601353A (en) * 2008-02-01 2014-06-27 Chromocell Corp Cell lines and methods for making and using them
US20150374705A1 (en) 2012-02-14 2015-12-31 Shanghai Institues for Biological Sciences Substances for treatment or relief of pain
CN106854207B (zh) 2015-12-08 2019-10-29 上海赛默罗生物科技有限公司 呔嗪类衍生物、其制备方法、药物组合物和用途
US11512089B2 (en) 2018-03-12 2022-11-29 Shanghai SIMR Biotechnology Co., Ltd Substituted [1,2,4]triazolo[3,4-a]phthalazines as modulators of GABAA receptor activity
CN112979655A (zh) 2019-12-16 2021-06-18 上海赛默罗生物科技有限公司 三唑并哒嗪类衍生物、其制备方法、药物组合物和用途
IL310708A (en) 2021-08-12 2024-04-01 Shanghai Simr Biotechnology Co Ltd The history of converted triazole, a method for its preparation, its pharmaceutical preparation and its use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9112504D0 (en) * 1991-06-11 1991-07-31 Merck Sharp & Dohme Cell line
US5166066A (en) * 1991-07-11 1992-11-24 The Upjohn Company Transformed cells comprising GABAA receptors

Also Published As

Publication number Publication date
ES2296064T3 (es) 2008-04-16
ES2251011T3 (es) 2006-04-16
EP0673419B1 (de) 1998-09-09
EP1605046A1 (de) 2005-12-14
EP0856581A2 (de) 1998-08-05
DE69333923D1 (de) 2006-01-05
DE69320985T2 (de) 1999-05-12
JPH08504330A (ja) 1996-05-14
DE69334187D1 (de) 2008-01-03
EP1605046B1 (de) 2007-11-21
EP0856581A3 (de) 1999-11-24
EP0673419A1 (de) 1995-09-27
ATE170921T1 (de) 1998-09-15
AU680852B2 (en) 1997-08-14
AU5655494A (en) 1994-07-04
US5652100A (en) 1997-07-29
ATE311449T1 (de) 2005-12-15
DE69333923T2 (de) 2006-08-03
DE69334187T2 (de) 2008-10-09
DE69320985D1 (de) 1998-10-15
WO1994013799A1 (en) 1994-06-23
JP3464672B2 (ja) 2003-11-10
EP0856581B1 (de) 2005-11-30

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