DK0852232T3 - Cykliske peptidforbindelser til behandling af smerte og deres fremstillingsproces - Google Patents
Cykliske peptidforbindelser til behandling af smerte og deres fremstillingsprocesInfo
- Publication number
- DK0852232T3 DK0852232T3 DK97309757T DK97309757T DK0852232T3 DK 0852232 T3 DK0852232 T3 DK 0852232T3 DK 97309757 T DK97309757 T DK 97309757T DK 97309757 T DK97309757 T DK 97309757T DK 0852232 T3 DK0852232 T3 DK 0852232T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyclic peptide
- treatment
- peptide compounds
- pain
- manufacturing process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- C07K5/126—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Toxicology (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB9601352 | 1996-12-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0852232T3 true DK0852232T3 (da) | 2002-04-22 |
Family
ID=11004499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97309757T DK0852232T3 (da) | 1996-12-04 | 1997-12-03 | Cykliske peptidforbindelser til behandling af smerte og deres fremstillingsproces |
Country Status (10)
Country | Link |
---|---|
US (1) | US5885959A (es) |
EP (1) | EP0852232B1 (es) |
JP (1) | JP3521110B2 (es) |
AT (1) | ATE211484T1 (es) |
BR (1) | BR9706222A (es) |
CA (1) | CA2223360C (es) |
DE (1) | DE69709841T2 (es) |
DK (1) | DK0852232T3 (es) |
ES (1) | ES2169325T3 (es) |
MX (1) | MX9709494A (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX9709494A (es) * | 1996-12-04 | 1998-07-31 | Pfizer | Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos. |
ES2338789T3 (es) | 2003-06-18 | 2010-05-12 | Tranzyme Pharma Inc. | Antagonistas macrociclicos del receptor de motilina. |
WO2016007956A2 (en) | 2014-07-11 | 2016-01-14 | University Of Kansas | Cyclic tetrapeptide stereoisomers |
ES2924903T3 (es) * | 2017-01-20 | 2022-10-11 | Univ Kansas | Péptidos macrocíclicos para uso en el tratamiento de un cáncer de próstata o mama |
AU2019239088A1 (en) | 2018-03-23 | 2020-10-22 | University Of Kansas | Cyclic tetrapeptide analogs |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0255224A3 (en) * | 1986-06-30 | 1990-04-18 | Merck & Co. Inc. | Cyclic and bridged cyclic somatostatin analogs useful as analgesic agents |
CA2090171A1 (en) * | 1993-02-23 | 1994-08-24 | Peter W. Schiller | Opioid receptor antagonists, their synthesis and use as analgesic and immunosuppressive compounds |
US5521156A (en) * | 1994-02-03 | 1996-05-28 | Merrell Pharmaceuticals Inc. | Cyclic neurokinin A antagonists |
IS4261A (is) * | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra |
MX9709494A (es) * | 1996-12-04 | 1998-07-31 | Pfizer | Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos. |
-
1996
- 1996-12-04 MX MX9709494A patent/MX9709494A/es not_active IP Right Cessation
-
1997
- 1997-12-03 DK DK97309757T patent/DK0852232T3/da active
- 1997-12-03 CA CA002223360A patent/CA2223360C/en not_active Expired - Fee Related
- 1997-12-03 US US08/999,627 patent/US5885959A/en not_active Expired - Fee Related
- 1997-12-03 ES ES97309757T patent/ES2169325T3/es not_active Expired - Lifetime
- 1997-12-03 AT AT97309757T patent/ATE211484T1/de not_active IP Right Cessation
- 1997-12-03 EP EP97309757A patent/EP0852232B1/en not_active Expired - Lifetime
- 1997-12-03 DE DE69709841T patent/DE69709841T2/de not_active Expired - Fee Related
- 1997-12-04 BR BR9706222A patent/BR9706222A/pt unknown
- 1997-12-04 JP JP34869797A patent/JP3521110B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
BR9706222A (pt) | 1999-06-01 |
CA2223360A1 (en) | 1998-06-04 |
JPH111492A (ja) | 1999-01-06 |
CA2223360C (en) | 2000-05-30 |
JP3521110B2 (ja) | 2004-04-19 |
DE69709841T2 (de) | 2002-08-22 |
DE69709841D1 (de) | 2002-02-28 |
MX9709494A (es) | 1998-07-31 |
US5885959A (en) | 1999-03-23 |
EP0852232A1 (en) | 1998-07-08 |
ATE211484T1 (de) | 2002-01-15 |
EP0852232B1 (en) | 2002-01-02 |
ES2169325T3 (es) | 2002-07-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0854874T3 (da) | Makrocykliske lactonforbindelser og fremgangsmåde til fremstilling af disse | |
DK0723540T3 (da) | Tricykliske amid- og urinstofderivater til inhibering af funktion af G-protein og til behandling af proliferative sygdomme | |
Ohfune et al. | An efficient route to 1, 3-amino hydroxyl system via electrophilic lactonization of 2-amino-4-pentenoic acid derivatives. Stereoselective synthesis of (−)-bulgecinine | |
ATE217635T1 (de) | Zyklische peptide mit antifungischer wirkung und verfahren zu ihrer herstellung | |
AU4624097A (en) | Thio acid derived monocyclic (n)-heterocyclics as anticoagulants | |
SG43768A1 (en) | Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative dieases | |
DE60229267D1 (de) | Oxopyrrolidin verbindungen, verfahren zur herstellung dieser verbindungen und deren verwendung zur herstellung von levetiracetam und analogen | |
SE9904129D0 (sv) | Novel compounds | |
DK0852232T3 (da) | Cykliske peptidforbindelser til behandling af smerte og deres fremstillingsproces | |
IE882274L (en) | Aralkylaminoalkoxyphenyl derivatives | |
HUP0204069A2 (hu) | Új eljárás leflunomid előállítására és a leflunomid új kristályformája és ezt tartalmazó gyógyszerkészítmény | |
MY113863A (en) | Method for preparing n, n' - disubstituted cyclic ureas | |
ATE166354T1 (de) | Azabicycloarylacetylen- und arylenynoxine als cholinergische mittel und verfahren zur behandlung | |
NZ336793A (en) | Method for stabilizing peptides by adding an organic acid and then lyophilizing the peptide mixture | |
BR9408223A (pt) | Composto derivado de 4-benzoilisoxazol processo de preparação composição herbicida método de controle herbicida e compostos intermediarios | |
ATE11217T1 (de) | Antibiotische substanzen, verfahren zu deren herstellung und deren zusammensetzungen; stamm von staphylococcus epidermidis, welcher diese antibiotische substanz produziert und deren zusammensetzungen. | |
EP0885891A4 (en) | ISOXAZOLE DERIVATIVES | |
Matsunaga et al. | Cribrochalinamine oxides A and B, antifungal β-substituted pyridines with an azomethine N-oxide from a marine sponge Cribrochalina sp. | |
EE05182B1 (et) | Asendatud homopiperidlbensimidasooli analoog, meetod selle valmistamiseks ning seda sisaldav farmatseutiline kompositsioon | |
EA200501734A1 (ru) | Способ получения (4-гидрокси-6-оксотетрагидропиран-2-ил)ацетонитрила и его производных | |
ATE266652T1 (de) | Als entzündungshemmende mittel nützliche dihydrobenzofurane und verwandte verbindungen | |
EA199901059A1 (ru) | Способ получения энантиомерно обогащенных n-производных лактамов | |
NO984206L (no) | Fremgangsmaate for fremstilling av N-beskyttende D-prolinderivater | |
Bringmann | A first biosynthetic proposal for the in vivo formation of naturally occurring diazepam-like 1, 4-benzodiazepines | |
Hasuoka et al. | Synthesis and anti-Helicobacter pylori activity of pyloricidin derivatives II. The combination of amino acid residues in the dipeptidic moiety and its effect on the anti-Helicobacter pylori activity |