MX9709494A - Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos. - Google Patents

Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.

Info

Publication number
MX9709494A
MX9709494A MX9709494A MX9709494A MX9709494A MX 9709494 A MX9709494 A MX 9709494A MX 9709494 A MX9709494 A MX 9709494A MX 9709494 A MX9709494 A MX 9709494A MX 9709494 A MX9709494 A MX 9709494A
Authority
MX
Mexico
Prior art keywords
peptidic compounds
same
cyclic
production
compositions containing
Prior art date
Application number
MX9709494A
Other languages
English (en)
Inventor
Hideo Hirai
Nakao Kojima
Hiroyuki Nishida
Toshiyuki Saito
Nobuji Yoshikawa
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9709494A publication Critical patent/MX9709494A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/126—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Esta invencion provee procedimientos para producir compuestos peptídicos cíclicos novedosos, que comprende cultivar Ctenomyces serratus FERM BP-5731 y después aislar los compuestos peptídicos cíclicos del caldo de fermentacion. Los compuestos producidos mediante estos procedimientos incluyen un compuesto pçeptido cíclico de la siguiente formula (I): la presente invencion también se refiere a una composicion farmacéutica que comprende la misma, la cual esutil en el tratamiento de dolor severo, desintoxicacion por dependencia a narcoticos o intoxicacion aguda por narcoticos y similares.
MX9709494A 1996-12-04 1996-12-04 Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos. MX9709494A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9601352 1996-12-04

Publications (1)

Publication Number Publication Date
MX9709494A true MX9709494A (es) 1998-07-31

Family

ID=11004499

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9709494A MX9709494A (es) 1996-12-04 1996-12-04 Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.

Country Status (10)

Country Link
US (1) US5885959A (es)
EP (1) EP0852232B1 (es)
JP (1) JP3521110B2 (es)
AT (1) ATE211484T1 (es)
BR (1) BR9706222A (es)
CA (1) CA2223360C (es)
DE (1) DE69709841T2 (es)
DK (1) DK0852232T3 (es)
ES (1) ES2169325T3 (es)
MX (1) MX9709494A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9709494A (es) * 1996-12-04 1998-07-31 Pfizer Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
US10259843B2 (en) 2014-07-11 2019-04-16 University Of Kansas Cyclic tetrapeptide stereoisomers
WO2018136843A1 (en) * 2017-01-20 2018-07-26 University Of Kansas Macrocyclic peptides to decrease c-myc protein levels and reduce cancer cell growth
KR20220038266A (ko) 2018-03-23 2022-03-28 유니버시티 오브 캔사스 시클릭 테트라펩티드 유사체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0255224A3 (en) * 1986-06-30 1990-04-18 Merck & Co. Inc. Cyclic and bridged cyclic somatostatin analogs useful as analgesic agents
CA2090171A1 (en) * 1993-02-23 1994-08-24 Peter W. Schiller Opioid receptor antagonists, their synthesis and use as analgesic and immunosuppressive compounds
US5521156A (en) * 1994-02-03 1996-05-28 Merrell Pharmaceuticals Inc. Cyclic neurokinin A antagonists
IS4261A (is) * 1994-02-21 1995-08-22 Astra Aktiebolag Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
MX9709494A (es) * 1996-12-04 1998-07-31 Pfizer Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos.

Also Published As

Publication number Publication date
US5885959A (en) 1999-03-23
EP0852232A1 (en) 1998-07-08
DE69709841D1 (de) 2002-02-28
BR9706222A (pt) 1999-06-01
EP0852232B1 (en) 2002-01-02
ES2169325T3 (es) 2002-07-01
JPH111492A (ja) 1999-01-06
JP3521110B2 (ja) 2004-04-19
CA2223360A1 (en) 1998-06-04
ATE211484T1 (de) 2002-01-15
CA2223360C (en) 2000-05-30
DK0852232T3 (da) 2002-04-22
DE69709841T2 (de) 2002-08-22

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees